Production Method 1

867-13-0

62506-63-2

130472-39-8

3307-88-8

81239-01-2

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Water
1.2 Solvents: Dimethylformamide
2.1 Solvents: Ethanol
3.1 Reagents: Potassium carbonate Solvents: Diethyl ether ,  Water

Reference

(E)-Ethyl β-formylacrylate dimethylhydrazone methiodide: a reactive and convenient precursor of (E)-ethyl β-formylacrylate

Schmitt, M.; et al, Tetrahedron Letters, 1990, 31(15), 2145-8

Production Method 2

130472-38-7

130472-39-8

3307-88-8

81239-01-2

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Diethyl ether ,  Water

Reference

(E)-Ethyl β-formylacrylate dimethylhydrazone methiodide: a reactive and convenient precursor of (E)-ethyl β-formylacrylate

Schmitt, M.; et al, Tetrahedron Letters, 1990, 31(15), 2145-8

Production Method 3

130472-36-5

130472-39-8

3307-88-8

81239-01-2

Reaction Conditions

1.1 Solvents: Ethanol
2.1 Reagents: Potassium carbonate Solvents: Diethyl ether ,  Water

Reference

(E)-Ethyl β-formylacrylate dimethylhydrazone methiodide: a reactive and convenient precursor of (E)-ethyl β-formylacrylate

Schmitt, M.; et al, Tetrahedron Letters, 1990, 31(15), 2145-8

Raw materials

• Triethyl phosphonoacetate
• Ethanedial, mono(dimethylhydrazone)
• Hydrazinium, 2-(4-ethoxy-4-oxo-2-butenylidene)-1,1,1-trimethyl-, iodide, (,E)- (9CI)
• (Z)-2-(4-ethoxy-3-morpholino-4-oxobutylidene)-1,1,1-trimethylhydrazin-1-ium iodide

Preparation Products

• (130472-39-8)
• 3-ethoxycarbonylacrylonitrile (3307-88-8)
• 2-Propenoic acid, 3-(4-morpholinyl)-, ethyl ester, (E)- (81239-01-2)

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