Cas no 128427-05-4 ((2S)-2-ethylpiperazine;dihydrochloride)

(2S)-2-Ethylpiperazine dihydrochloride is a chiral piperazine derivative widely utilized as a key intermediate in pharmaceutical synthesis and asymmetric catalysis. Its stereospecific (S)-configuration ensures high enantioselectivity in the production of biologically active compounds, particularly in CNS-targeting drugs and chiral ligands. The dihydrochloride salt form enhances stability and solubility, facilitating handling and storage under standard laboratory conditions. This compound is valued for its consistent purity (>98%) and reliable performance in nucleophilic substitution and acylation reactions. Its rigid piperazine backbone contributes to structural precision in complex molecular architectures, making it a preferred choice for medicinal chemistry and process optimization.

(2S)-2-ethylpiperazine;dihydrochloride structure

128427-05-4 structure

Product Name:(2S)-2-ethylpiperazine;dihydrochloride

CAS No:128427-05-4

MF:C₆H₁₆Cl₂N₂

MW:187.110639572144

MDL:MFCD13191713

CID:835622

PubChem ID:51051650

Update Time:2025-10-08

(2S)-2-ethylpiperazine;dihydrochloride Chemical and Physical Properties

Names and Identifiers

- (S)-2-Ethylpiperazine dihydrochloride
- (S)-2-ETHYL-PIPERAZINE 2HCl
- (S)-2-methylpiperidine-2-carboxylic acid, HCl salt
- 4 weeks
- (2S)-2-ethylpiperazine,dihydrochloride
- (S)-2-ETHYL-PIPERAZINE-2HCl
- (S)-2-ethylpiperazine (diHydrochloride)
- (S)-2-ETHYL-PIPERAZINE DIHYDROCHLORIDE
- 5419AA
- (S)-2-ethylpiperazine(dihydrochloride)
- BC688420
- ST2402799
- AX8163872
- AB0000516
- (2S)-2-Ethylpiperazine--hydrogen chloride (1/2)
- (2S)-2-ethylpiperazine;dihydrochloride
- DTXSID20679631
- CS-M0319
- CS-13202
- (S)-2-ethylpiperazinedihydrochloride
- (2S)-2-ETHYLPIPERAZINE DIHYDROCHLORIDE
- Piperazine, 2-ethyl-, dihydrochloride, (S)- (9CI)
- I11833
- (S)-2-ETHYL-PIPERAZINE 97+%
- 128427-05-4
- AKOS015923437
- MFCD13191713
- MDL： MFCD13191713
- Inchi： 1S/C6H14N2.2ClH/c1-2-6-5-7-3-4-8-6;;/h6-8H,2-5H2,1H3;2*1H/t6-;;/m0../s1
- InChI Key： VCKAKBROIJTVJI-ILKKLZGPSA-N
- SMILES： Cl.Cl.N1CCNC[C@@H]1CC

Computed Properties

Exact Mass: 186.06900
Monoisotopic Mass: 186.0690539g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 10
Rotatable Bond Count: 1
Complexity: 63.5
Covalently-Bonded Unit Count: 3
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 24.1

Experimental Properties

PSA: 24.06000
LogP: 2.21940

(2S)-2-ethylpiperazine;dihydrochloride Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Alichem	A139002626-1g	(S)-2-Ethylpiperazine dihydrochloride	128427-05-4	95%	1g	$299.52	2022-04-03
Chemenu	CM126823-100g	(S)-2-ethylpiperazine dihydrochloride	128427-05-4	95%	100g	$5152	2021-08-05
TRC	E938813-10mg	(S)-2-ETHYLPIPERAZINE	128427-05-4		10mg	$ 50.00	2022-06-05
TRC	E938813-50mg	(S)-2-ETHYLPIPERAZINE	128427-05-4		50mg	$ 65.00	2022-06-05
TRC	E938813-100mg	(S)-2-ETHYLPIPERAZINE	128427-05-4		100mg	$ 80.00	2022-06-05
Apollo Scientific	OR946496-1g	(2S)-2-Ethylpiperazine dihydrochloride	128427-05-4	98+%	1g	￡871.00	2025-02-21
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	S26760-100mg	(S)-2-Ethylpiperazine dihydrochloride	128427-05-4		100mg	￥1012.0	2021-09-07
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	S26760-1g	(S)-2-Ethylpiperazine dihydrochloride	128427-05-4		1g	￥2572.0	2021-09-07
NAN JING YAO SHI KE JI GU FEN Co., Ltd.	PB05952-1-100mg	(2S)-2-ethylpiperazine;dihydrochloride	128427-05-4	95%	100mg	￥771.0	2024-04-25
NAN JING YAO SHI KE JI GU FEN Co., Ltd.	PB05952-1-250mg	(2S)-2-ethylpiperazine;dihydrochloride	128427-05-4	95%	250mg	￥1290.0	2024-04-25