Cas no 207284-20-6 ((2S)-2-ethylpiperazine)

(2S)-2-Ethylpiperazine is a chiral piperazine derivative characterized by its stereospecific (S)-configuration at the 2-position, where an ethyl substituent is introduced. This structural feature enhances its utility as a versatile building block in asymmetric synthesis, particularly for pharmaceuticals and fine chemicals requiring enantioselectivity. The compound's rigid piperazine core provides a stable scaffold for modifying physicochemical properties, while the ethyl group offers tunable lipophilicity. Its high purity and defined stereochemistry make it valuable for designing chiral ligands, catalysts, or bioactive intermediates with improved selectivity. The compound is typically handled under inert conditions due to potential sensitivity, and its reactivity favors N-functionalization or salt formation.
(2S)-2-ethylpiperazine structure
(2S)-2-ethylpiperazine structure
Product Name:(2S)-2-ethylpiperazine
CAS No:207284-20-6
MF:C6H14N2
MW:114.188761234283
CID:829834
PubChem ID:11240458
Update Time:2025-11-01

(2S)-2-ethylpiperazine Chemical and Physical Properties

Names and Identifiers

    • (R)-2-ethylpiperazine
    • (2S)-2-ethylpiperazine
    • (R)-2-ETHYL-PIPERAZINE
    • (S)-2-ETHYL-PIPERAZINE
    • (S)-(+)-ethyl 2-ethoxy-4-< 2-< < 3-methyl-1-< 2-(1-piperidinyl)phenyl> butyl> amino> -2-oxoethyl> -benzoate
    • (S)-2-ethyl piperazine
    • (S)-Ethyl 2-ethoxy-4-(((N-(1-(2-piperidinophenyl)-3-methyl-1-butyl)amino)carbonyl)methyl)benzoate
    • (S)-Repaglinide ethyl ester
    • 2-(S)-ethylpiperazine
    • 2-ethoxy-4-
    • CTK8E8147
    • ethyl (S)-2-ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoate
    • SureCN391046
    • SCHEMBL336761
    • DTXSID001314402
    • (S)(+)-2-ethylpiperazine
    • BS-53171
    • (S)-2-Ethylpiperazine
    • AKOS025401346
    • AC-11869
    • DXOHZOPKNFZZAD-LURJTMIESA-N
    • Piperazine, 2-ethyl-, (2S)-
    • 207284-20-6
    • MDL： MFCD07373041
    • Inchi： 1S/C6H14N2/c1-2-6-5-7-3-4-8-6/h6-8H,2-5H2,1H3/t6-/m0/s1
    • InChI Key： DXOHZOPKNFZZAD-LURJTMIESA-N
    • SMILES： N1CCNC[C@@H]1CC

Computed Properties

  • Exact Mass: 114.115698455g/mol
  • Monoisotopic Mass: 114.115698455g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 1
  • Complexity: 63.5
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.1
  • Topological Polar Surface Area: 24.1?2

Experimental Properties

  • Density: 0.839
  • Boiling Point: 169.5 oC
  • Flash Point: 55.8 oC

(2S)-2-ethylpiperazine Pricemore >>

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(2S)-2-ethylpiperazine Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:207284-20-6)(2S)-2-ethylpiperazine
Order Number:A856056
Stock Status:in Stock
Quantity:5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:58
Price ($):152.0

(2S)-2-ethylpiperazine Related Literature

Additional information on (2S)-2-ethylpiperazine

Comprehensive Overview of (2S)-2-ethylpiperazine (CAS No. 207284-20-6): Properties, Applications, and Industry Trends

(2S)-2-ethylpiperazine (CAS No. 207284-20-6) is a chiral piperazine derivative with significant relevance in pharmaceutical and chemical research. Its stereospecific structure and ethyl substitution make it a valuable intermediate for synthesizing bioactive compounds. As the demand for enantiomerically pure chemicals grows, this compound has garnered attention for its role in asymmetric synthesis and drug development.

Recent trends in green chemistry and sustainable synthesis have spurred interest in optimizing the production of (2S)-2-ethylpiperazine. Researchers are exploring catalytic methods to reduce waste and improve yield, aligning with global initiatives like the UN Sustainable Development Goals. Additionally, its potential in central nervous system (CNS) drug design is a hot topic, as evidenced by rising searches for "piperazine derivatives in neurology" and "chiral building blocks for APIs."

The compound's physicochemical properties—such as its boiling point, solubility, and optical rotation—are critical for formulation scientists. Analytical techniques like HPLC and NMR are routinely employed to verify its purity, a key concern for buyers searching for "high-purity (2S)-2-ethylpiperazine suppliers." Regulatory compliance, including REACH and GMP standards, further underscores its industrial importance.

In the pharmaceutical industry, (2S)-2-ethylpiperazine serves as a precursor for antidepressants, antipsychotics, and antivirals. Its structural versatility allows for modifications that enhance drug bioavailability and target selectivity. This aligns with the growing market for personalized medicine, where searches for "customized drug intermediates" have surged by 40% year-over-year.

Beyond pharmaceuticals, the compound finds niche applications in agrochemicals and material science. For instance, its incorporation into polyurethane catalysts improves polymer performance, addressing queries like "piperazine-based catalysts for coatings." However, challenges such as scalability and cost-efficiency remain focal points for manufacturers, driving innovations in continuous flow chemistry.

To meet evolving industry needs, suppliers are offering (2S)-2-ethylpiperazine in varying pack sizes and grades, from research-use-only to GMP-compliant batches. This flexibility caters to diverse clientele, from academic labs searching for "small-scale chiral amines" to industrial players requiring "bulk piperazine derivatives."

In conclusion, (2S)-2-ethylpiperazine (CAS No. 207284-20-6) exemplifies the intersection of chiral chemistry and applied science. Its multifaceted applications and alignment with sustainability goals position it as a compound of enduring relevance. Future research may unlock novel uses, particularly in bioconjugation and smart materials, further expanding its commercial and scientific footprint.

207284-20-6 ((2S)-2-ethylpiperazine) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:207284-20-6)(2S)-2-ethylpiperazine
A856056
Purity:99%
Quantity:5g
Price ($):152.0
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