Cas no 127345-21-5 (Rebaudioside G)

Rebaudioside G is a high-purity steviol glycoside derived from the leaves of Stevia rebaudiana. It is a non-caloric sweetener with a clean, sugar-like taste profile and minimal bitterness or aftertaste compared to other steviol glycosides. Its molecular structure contributes to enhanced solubility and stability in various food and beverage applications. Rebaudioside G exhibits a sweetness potency approximately 200–300 times that of sucrose, making it an efficient sugar substitute. It is heat-stable and pH-stable, suitable for use in baked goods, dairy products, and acidic beverages. As a naturally sourced sweetener, it aligns with clean-label trends and is generally recognized as safe (GRAS) for consumption.
Rebaudioside G structure
Rebaudioside G structure
Product Name:Rebaudioside G
CAS No:127345-21-5
MF:C38H60O18
MW:804.8722
CID:1072183
Update Time:2025-10-24

Rebaudioside G Chemical and Physical Properties

Names and Identifiers

    • REBAUDIOSIDE G(P)
    • Rebaudioside G
    • (4alpha)-13-[(3-O-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic acid beta-D-glucopyranosyl ester
    • [3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1R,4S,5R,9S,10R,13S)-13-[3,5-dihydroxy-6-(hydroxymethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylate
    • [(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] (4S,5R,9S,13S)-13-[(2S,3R,4S,5R,6R)-3
    • Q63398350
    • Inchi： 1S/C38H60O18/c1-16-11-37-9-5-20-35(2,7-4-8-36(20,3)34(50)55-32-28(48)26(46)23(43)18(13-40)52-32)21(37)6-10-38(16,15-37)56-33-29(49)30(24(44)19(14-41)53-33)54-31-27(47)25(45)22(42)17(12-39)51-31/h17-33,39-49H,1,4-15H2,2-3H3/t17-,18-,19-,20+,21+,22-,23-,24-,25+,26+,27-,28-,29-,30+,31+,32+,33+,35-,36-,37-,38+/m1/s1
    • InChI Key： OKPSCKUJXYCMPR-GXTBKCSKSA-N
    • SMILES： O([C@@]1([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[C@@]1([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[H])O[H])O[H])[C@@]12C(=C([H])[H])C([H])([H])[C@]3(C([H])([H])C([H])([H])[C@]4([H])[C@@](C(=O)O[C@@]5([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O5)O[H])O[H])O[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]4(C([H])([H])[H])[C@]3([H])C([H])([H])C1([H])[H])C2([H])[H]

Computed Properties

  • Exact Mass: 804.37796506 g/mol
  • Monoisotopic Mass: 804.37796506 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 11
  • Hydrogen Bond Acceptor Count: 18
  • Heavy Atom Count: 56
  • Rotatable Bond Count: 10
  • Complexity: 1450
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 21
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -1.2
  • Topological Polar Surface Area: 295
  • Molecular Weight: 804.9

Experimental Properties

  • Color/Form: Powder
  • Density: 1.53±0.1 g/cm3 (20 oC 760 Torr),
  • Solubility: Almost insoluble (0.017 g/l) (25 o C),

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Rebaudioside G Suppliers

Hubei Cuiyuan Biotechnology Co.,Ltd
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(CAS:127345-21-5)RebaudiosideG
Order Number:CRN0165
Stock Status:in stock
Quantity:5mg/20mg/50mg
Purity:≥98%
Pricing Information Last Updated:Friday, 14 March 2025 10:55
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Rebaudioside G Related Literature

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Additional information on Rebaudioside G

Rebaudioside G: A Comprehensive Overview

Rebaudioside G, also known by its CAS number 127345-21-5, is a naturally occurring compound that has garnered significant attention in recent years due to its unique properties and potential applications. This compound, which belongs to the class of glycosides, is primarily found in the Stevia rebaudiana plant, commonly known as stevia. The plant has been used for centuries in South America for its sweet-tasting leaves, and modern research has uncovered a wealth of beneficial compounds within it, including Rebaudioside G.

The chemical structure of Rebaudioside G is characterized by a diterpenoid backbone with a unique glycosylation pattern. This structure contributes to its sweet taste profile and stability under various conditions. Recent studies have focused on understanding the molecular mechanisms behind its sweetness and how it can be optimized for use in food and beverage applications. For instance, researchers have explored the impact of different pH levels and temperatures on the stability of Rebaudioside G, revealing that it maintains its sweetness even under challenging conditions.

One of the most promising aspects of Rebaudioside G is its potential as a natural sweetener. With the global demand for low-calorie and sugar-free alternatives on the rise, compounds like Rebaudioside G offer a viable solution. Unlike artificial sweeteners, which have been linked to various health concerns, natural sweeteners derived from stevia are generally considered safe and beneficial. Recent clinical trials have demonstrated that Rebaudioside G can effectively reduce sugar intake without compromising taste quality, making it an attractive option for manufacturers looking to cater to health-conscious consumers.

Beyond its role as a sweetener, Rebaudioside G has shown potential in other areas of health and wellness. Emerging research suggests that it may possess anti-inflammatory and antioxidant properties, which could be harnessed for therapeutic purposes. For example, a study published in 2023 investigated the effects of Rebaudioside G on inflammatory markers in laboratory models and found significant reductions in cytokine production. These findings open up new avenues for exploring its use in managing chronic inflammatory conditions.

The production and extraction of Rebaudioside G have also been subjects of recent innovation. Traditional methods involve aqueous extraction followed by chromatographic purification, but these processes can be time-consuming and costly. To address this, scientists have developed novel techniques such as enzymatic hydrolysis and membrane filtration, which improve yield and efficiency. These advancements are crucial for scaling up production to meet the growing demand for Rebaudioside G in both food and pharmaceutical industries.

In terms of market applications, Rebaudioside G is already being incorporated into a variety of products, including beverages, confectionery, and dietary supplements. Its ability to enhance flavor profiles without adding calories makes it an ideal ingredient for weight management products. Additionally, its stability under heat makes it suitable for use in baked goods and other processed foods where traditional sweeteners might degrade.

Looking ahead, the future of Rebaudioside G seems bright as researchers continue to uncover new applications and benefits. Collaborative efforts between academia and industry are expected to drive further innovation in its production methods and applications. As consumer awareness about the importance of natural ingredients grows, compounds like Rebaudioside G are poised to play a pivotal role in shaping the future of food science and healthcare.

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(CAS:127345-21-5)RebaudiosideG
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