Cas no 1261918-20-0 (2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol)

2-Fluoro-5-(2-fluoro-3-methoxyphenyl)phenol is a fluorinated phenolic compound featuring a methoxy-substituted biphenyl core. Its unique structure, incorporating two fluorine atoms and a methoxy group, enhances its reactivity and selectivity in synthetic applications, particularly in pharmaceutical and agrochemical intermediates. The fluorine substituents improve metabolic stability and binding affinity, making it valuable for drug discovery. The phenol group allows for further functionalization, enabling versatile derivatization. This compound exhibits favorable physicochemical properties, including moderate solubility in organic solvents, facilitating its use in cross-coupling and other advanced synthetic transformations. Its well-defined structure ensures consistency in research and industrial applications.
2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol structure
1261918-20-0 structure
Product Name:2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol
CAS No:1261918-20-0
MF:C13H10F2O2
MW:236.214110851288
MDL:MFCD18313763
CID:1223056
PubChem ID:53219443
Update Time:2025-06-09

2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol Chemical and Physical Properties

Names and Identifiers

    • 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol
    • DTXSID10684279
    • MFCD18313763
    • 1261918-20-0
    • 2',4-Difluoro-3'-methoxy[1,1'-biphenyl]-3-ol
    • 2-Fluoro-5-(2-fluoro-3-methoxyphenyl)phenol, 95%
    • MDL: MFCD18313763
    • Inchi: 1S/C13H10F2O2/c1-17-12-4-2-3-9(13(12)15)8-5-6-10(14)11(16)7-8/h2-7,16H,1H3
    • InChI Key: PPZCCRPMHFRIND-UHFFFAOYSA-N
    • SMILES: FC1C(=CC=CC=1C1C=CC(=C(C=1)O)F)OC

Computed Properties

  • Exact Mass: 236.06488588g/mol
  • Monoisotopic Mass: 236.06488588g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 2
  • Complexity: 250
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.4
  • Topological Polar Surface Area: 29.5?2

2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB319799-5 g
2-Fluoro-5-(2-fluoro-3-methoxyphenyl)phenol, 95%; .
1261918-20-0 95%
5 g
€1,159.00 2023-07-19
abcr
AB319799-5g
2-Fluoro-5-(2-fluoro-3-methoxyphenyl)phenol, 95%; .
1261918-20-0 95%
5g
€1159.00 2025-02-13

Additional information on 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol

Comprehensive Overview of 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol (CAS No. 1261918-20-0): Properties, Applications, and Industry Insights

2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol (CAS No. 1261918-20-0) is a fluorinated phenolic compound that has garnered significant attention in pharmaceutical and agrochemical research due to its unique structural features. The presence of fluoro substituents and a methoxyphenyl group enhances its reactivity and potential as a building block for complex molecules. This compound is often explored for its role in drug discovery, particularly in the development of kinase inhibitors and antimicrobial agents, aligning with the growing demand for targeted therapies and precision medicine.

In recent years, the scientific community has shown increased interest in fluorinated aromatic compounds like 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol, driven by their ability to improve metabolic stability and bioavailability in drug candidates. Searches for terms such as "fluoro-phenol derivatives" and "CAS 1261918-20-0 applications" have surged, reflecting its relevance in medicinal chemistry and material science. Researchers are also investigating its potential in organic electronics, where fluorinated compounds contribute to enhanced charge transport properties.

The synthesis of 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol typically involves multi-step organic reactions, including cross-coupling and selective fluorination techniques. Advanced methods such as microwave-assisted synthesis and flow chemistry are being adopted to optimize yield and purity, addressing the industry's focus on green chemistry and sustainable manufacturing. These innovations resonate with the rising popularity of search queries like "eco-friendly synthesis of fluorophenols" and "CAS 1261918-20-0 suppliers."

From an analytical perspective, 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol is characterized using techniques such as HPLC, NMR spectroscopy, and mass spectrometry. Its molecular weight (250.22 g/mol) and logP value (predicted ~2.8) make it a candidate for lipophilic drug design, a topic frequently searched in pharmacokinetic studies. The compound’s solubility in organic solvents like DMSO and methanol further supports its utility in high-throughput screening assays.

Beyond pharmaceuticals, 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol is explored in crop protection formulations, where fluorinated phenols act as intermediates for herbicides and fungicides. This aligns with global trends toward sustainable agriculture and reduced environmental impact, topics dominating search engines under keywords like "fluoro-agrochemicals" and "CAS 1261918-20-0 safety data." Regulatory compliance, including REACH and FDA guidelines, is critical for its commercial adoption.

In conclusion, 2-fluoro-5-(2-fluoro-3-methoxyphenyl)phenol (CAS No. 1261918-20-0) represents a versatile compound with broad applications in life sciences and industrial chemistry. Its integration into AI-driven drug discovery platforms and automated synthesis workflows highlights its future potential. As research progresses, this compound is poised to address pressing challenges in healthcare and agriculture, making it a focal point for innovation and investment.

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