• 1. An approach to the structure and vibrational analysis of cis- and trans-3-chlorostyrene through IR/Raman and INS spectroscopies and theoretical ab initio/DFT calculations?
  J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
• 2. An inter-tangled network of redox-active and conducting polymers as a cathode for ultrafast rechargeable batteries
  Jieun Kim,Han-Saem Park,Tae-Hee Kim,Sung Yeol Kim,Hyun-Kon Song Phys. Chem. Chem. Phys., 2014,16, 5295-5300
• 3. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 4. Aggregation-induced emission based on a fluorinated macrocycle: visualizing spontaneous and ultrafast solid-state molecular motions at room temperature via F?F interactions?
  Mei Zhang,Jingjing Guo,Tingting Liu,Zhanyu He,Majeed Irfan,Zujin Zhao,Zhuo Zeng J. Mater. Chem. C, 2020,8, 14919-14924
• 5. An investigation of new infrared nonlinear optical material: BaCdSnSe4, and three new related centrosymmetric compounds: Ba2SnSe4, Mg2GeSe4, and Ba2Ge2S6?
  Kui Wu,Zhihua Yang,Shilie Pan Dalton Trans., 2015,44, 19856-19864

Introduction to 5-(4-Methylphenyl)-3-trifluoromethylphenol (CAS No. 1261889-07-9)

5-(4-Methylphenyl)-3-trifluoromethylphenol, identified by its Chemical Abstracts Service (CAS) number 1261889-07-9, is a specialized organic compound that has garnered significant attention in the field of pharmaceutical chemistry and medicinal research. This compound, featuring a unique structural arrangement of a methyl-substituted phenyl ring and a trifluoromethylphenol moiety, exhibits promising properties that make it a valuable candidate for further exploration in drug development.

The molecular structure of 5-(4-Methylphenyl)-3-trifluoromethylphenol consists of two aromatic rings connected by a hydroxyl group at the 3-position of one ring and a methyl group at the 4-position of the other. The presence of the trifluoromethyl group enhances the lipophilicity and metabolic stability of the compound, which are critical factors in pharmaceutical design. This structural feature, combined with its aromatic nature, positions it as a potential scaffold for developing novel therapeutic agents.

In recent years, there has been growing interest in phenolic compounds due to their diverse biological activities. 5-(4-Methylphenyl)-3-trifluoromethylphenol is no exception, as studies have begun to uncover its potential in various pharmacological contexts. Research has indicated that this compound may exhibit antioxidant, anti-inflammatory, and even anticancer properties. These findings are particularly intriguing given the increasing demand for natural product-inspired drug candidates that can complement existing therapeutic strategies.

The trifluoromethylphenol moiety in 5-(4-Methylphenyl)-3-trifluoromethylphenol is particularly noteworthy, as trifluoromethyl groups are known to modulate the electronic and steric properties of molecules. This modification can significantly influence the compound's interactions with biological targets, potentially enhancing its efficacy and selectivity. Furthermore, the methylphenyl component contributes to the compound's solubility and bioavailability, making it more amenable to formulation into viable drug products.

Current research efforts are focused on synthesizing derivatives of 5-(4-Methylphenyl)-3-trifluoromethylphenol to optimize its pharmacological profile. By systematically modifying its structure, scientists aim to identify analogs that exhibit improved potency, reduced toxicity, and enhanced target specificity. These studies often employ computational modeling and high-throughput screening techniques to accelerate the discovery process.

The pharmaceutical industry is increasingly leveraging advanced synthetic methodologies to explore novel compounds like 5-(4-Methylphenyl)-3-trifluoromethylphenol. Techniques such as combinatorial chemistry and flow synthesis have enabled researchers to generate libraries of related compounds rapidly, facilitating high-throughput screening for biologically active molecules. This approach has already led to several promising candidates entering preclinical development pipelines.

Beyond its potential in drug development, 5-(4-Methylphenyl)-3-trifluoromethylphenol may also find applications in other areas of chemical biology. For instance, its structural features could make it useful as an intermediate in synthesizing more complex molecules or as a tool compound for studying enzyme mechanisms. The compound's ability to interact with biological targets in unique ways opens up numerous possibilities for further scientific investigation.

The synthesis of 5-(4-Methylphenyl)-3-trifluoromethylphenol involves multi-step organic reactions that require precise control over reaction conditions. Advanced catalytic systems and green chemistry principles are being employed to improve yield and reduce environmental impact. These innovations not only enhance the efficiency of producing the compound but also align with broader efforts to promote sustainable chemical practices.

As research progresses, collaborations between academia and industry will be crucial in translating laboratory findings into clinical applications. The development of 5-(4-Methylphenyl)-3-trifluoromethylphenol and its derivatives represents a prime example of how fundamental chemical research can lead to tangible therapeutic benefits. By continuing to explore its potential, scientists hope to uncover new treatments for a variety of diseases.

In conclusion, 5-(4-Methylphenyl)-3-trifluoromethylphenol (CAS No. 1261889-07-9) is a structurally interesting compound with significant pharmaceutical promise. Its unique combination of functional groups makes it a versatile scaffold for drug discovery, while ongoing research continues to expand our understanding of its biological activities. As advancements in synthetic chemistry and computational biology accelerate, the future looks bright for this promising molecule and its potential contributions to medicine.

• 191724-12-6(4-(3-Trifluoromethylphenyl)phenol)
• 10355-13-2(4'-(Trifluoromethyl)-biphenyl-4-ol)
• 349-58-6(3,5-Bis(trifluoromethyl)phenol)
• 98-17-9(ALPHA,A,A-Trifluoro-m-cresol)
• 1261934-70-6(3-methyl-5-[4-(trifluoromethyl)phenyl]phenol)
• 1261496-90-5(2-methyl-5-[4-(trifluoromethyl)phenyl]phenol)
• 1261631-87-1(2-methyl-5-[3-(trifluoromethyl)phenyl]phenol)
• 1261987-41-0(3-methyl-5-[3-(trifluoromethyl)phenyl]phenol)
• 872258-58-7(2,6-Dimethyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-4-ol)
• 365426-93-3(3-(4-Trifluoromethylphenyl)phenol)