Production Method 1

878207-91-1

1260764-76-8

878207-92-2

Reaction Conditions

1.1 Reagents: Phosphorus oxychloride Solvents: 1,2-Dichloroethane ;  4 h, reflux
1.2 Reagents: Water ;  cooled

Reference

Synthesis and SAR study of pyrrolo[3,4-b]pyridin-7(6H)-one derivatives as melanin concentrating hormone receptor 1 (MCH-R1) antagonists

Lim, Chae Jo; Kim, Ji Young; Lee, Byung Ho; Oh, Kwang-Seok; Yi, Kyu Yang, Bioorganic & Medicinal Chemistry Letters, 2013, 23(6), 1736-1739

methyl 4-chloro-3-methyl-pyridine-2-carboxylate Raw materials

• 3-Methyl-2-pyridinecarboxylic acid 1-oxide methyl ester

methyl 4-chloro-3-methyl-pyridine-2-carboxylate Preparation Products

• methyl 4-chloro-3-methyl-pyridine-2-carboxylate (1260764-76-8)
• methyl 6-chloro-3-methylpyridine-2-carboxylate (878207-92-2)

• 1. An amino group functionalized metal–organic framework as a luminescent probe for highly selective sensing of Fe3+ ions?
  Zhonghua Xiang,Chuanqi Fang,Sanhua Leng,Dapeng Cao J. Mater. Chem. A, 2014,2, 7662-7665
• 2. An alumina stabilized graphene oxide wrapped SnO2 hollow sphere LIB anode with improved lithium storage?
  Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
• 3. An assay for the enzyme N-acetyl-β-d-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs)
  R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
• 4. An anti-leakage liquid metal thermal interface material
  Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
• 5. An amide probe as a selective Al3+ and Fe3+ sensor inside the HeLa and a549 cell lines: Pictet–Spengler reaction for the rapid detection of tryptophan amino acid?
  Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

• 1261564-12-8(Ethyl 4-chloro-3-methylpicolinate)
• 24782-23-8(2-Quinolinecarboxylic acid, 4-chloro-3-methyl-, ethyl ester)
• 886365-49-7(Methyl 5-chloro-3-methylpicolinate)
• 187222-17-9(Ethyl 4-Chloro-3,5-dimethylpicolinate)
• 59886-84-9(2-Acetoxymethyl-4-chloro-3-methylpyridine)
• 59718-84-2(Methyl 3-methylpyridine-2-carboxylate)
• 447461-22-5(4-chloro-3,5-dimethylpyridine-2-carboxylic acid)
• 1104455-41-5(methyl 4-chloro-5-methylpyridine-2-carboxylate)
• 1261739-13-2(Ethyl 4-chloro-5-methylpicolinate)
• 30235-20-2(4-chloro-3-methylpyridine-2-carboxylic acid)