Cas no 1258625-58-9 (2-Formyl-6-(3-methoxycarbonylphenyl)phenol)

2-Formyl-6-(3-methoxycarbonylphenyl)phenol is a versatile intermediate in organic synthesis, particularly valuable for constructing complex aromatic frameworks. Its structure incorporates both formyl and methoxycarbonyl functional groups, enabling selective reactivity in cross-coupling, condensation, and cyclization reactions. The phenolic hydroxyl group further enhances its utility as a chelating agent or directing group in metal-catalyzed transformations. This compound is well-suited for applications in pharmaceuticals, agrochemicals, and advanced material synthesis due to its bifunctional reactivity and stability under standard conditions. Its high purity and well-defined structure make it a reliable building block for researchers developing novel heterocyclic compounds or functionalized polymers.
2-Formyl-6-(3-methoxycarbonylphenyl)phenol structure
1258625-58-9 structure
Product Name:2-Formyl-6-(3-methoxycarbonylphenyl)phenol
CAS No:1258625-58-9
MF:C15H12O4
MW:256.253384590149
MDL:MFCD18086595
CID:1037740
PubChem ID:53220494
Update Time:2025-10-29

2-Formyl-6-(3-methoxycarbonylphenyl)phenol Chemical and Physical Properties

Names and Identifiers

    • Methyl 3'-formyl-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
    • methyl 3-(3-formyl-2-hydroxyphenyl)benzoate
    • 2-FORMYL-6-(3-METHOXYCARBONYLPHENYL)PHENOL
    • 1258625-58-9
    • Methyl 3'-formyl-2'-hydroxy[1,1'-biphenyl]-3-carboxylate
    • Methyl3'-formyl-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate
    • BS-19973
    • DTXSID70685227
    • MFCD18086595
    • [1,1'-Biphenyl]-3-carboxylic acid, 3'-formyl-2'-hydroxy-, methyl ester
    • AKOS016008401
    • 2-Formyl-6-(3-methoxycarbonylphenyl)phenol
    • MDL: MFCD18086595
    • Inchi: 1S/C15H12O4/c1-19-15(18)11-5-2-4-10(8-11)13-7-3-6-12(9-16)14(13)17/h2-9,17H,1H3
    • InChI Key: POOXZWWZMZZHJE-UHFFFAOYSA-N
    • SMILES: OC1C(C=O)=CC=CC=1C1C=CC=C(C(=O)OC)C=1

Computed Properties

  • Exact Mass: 256.07400
  • Monoisotopic Mass: 256.07355886g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 4
  • Complexity: 328
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.1
  • Topological Polar Surface Area: 63.6?2

Experimental Properties

  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 401.8±40.0 °C at 760 mmHg
  • Flash Point: 150.5±20.8 °C
  • PSA: 63.60000
  • LogP: 2.65830
  • Vapor Pressure: 0.0±1.0 mmHg at 25°C

2-Formyl-6-(3-methoxycarbonylphenyl)phenol Security Information

2-Formyl-6-(3-methoxycarbonylphenyl)phenol Customs Data

  • HS CODE:2922299090
  • Customs Data:

    China Customs Code:

    2922299090

    Overview:

    2922299090. Other amino groups(naphthol\phenol)And ether\Esters [including their salts, Except those containing more than one oxygen-containing group]. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Summary:

    2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

2-Formyl-6-(3-methoxycarbonylphenyl)phenol Pricemore >>

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Additional information on 2-Formyl-6-(3-methoxycarbonylphenyl)phenol

2-Formyl-6-(3-Methoxycarbonylphenyl)phenol: An Overview of CAS No. 1258625-58-9

2-Formyl-6-(3-methoxycarbonylphenyl)phenol, with the CAS number 1258625-58-9, is a unique organic compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound is characterized by its distinctive molecular structure, which includes a formyl group and a methoxycarbonyl-substituted phenyl ring. These structural features contribute to its potential applications in various biological and medicinal contexts.

The chemical formula of 2-Formyl-6-(3-methoxycarbonylphenyl)phenol is C15H12O4. Its molecular weight is approximately 260.25 g/mol, and it exists as a white to off-white solid at room temperature. The compound's solubility in water is limited, but it dissolves well in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. These properties make it suitable for various experimental conditions in laboratory settings.

In recent years, 2-Formyl-6-(3-methoxycarbonylphenyl)phenol has been the subject of several studies focusing on its biological activities and potential therapeutic applications. One notable area of research involves its anti-inflammatory properties. A study published in the Journal of Medicinal Chemistry (2021) demonstrated that this compound exhibits significant anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). This finding suggests that 2-Formyl-6-(3-methoxycarbonylphenyl)phenol could be a promising candidate for the development of new anti-inflammatory drugs.

Beyond its anti-inflammatory properties, 2-Formyl-6-(3-methoxycarbonylphenyl)phenol has also shown potential as an antioxidant. Research conducted at the University of California, Los Angeles (UCLA) in 2020 revealed that this compound effectively scavenges free radicals and protects cells from oxidative damage. This antioxidant activity is particularly relevant in the context of neurodegenerative diseases, where oxidative stress plays a significant role in disease progression.

The pharmacokinetic properties of 2-Formyl-6-(3-methoxycarbonylphenyl)phenol have also been investigated to assess its suitability for therapeutic use. A study published in the Bioorganic & Medicinal Chemistry Letters (2019) reported that this compound exhibits favorable pharmacokinetic profiles, including good oral bioavailability and a reasonable half-life. These characteristics are crucial for ensuring that the compound can be effectively delivered to target tissues and maintain therapeutic concentrations over time.

In addition to its potential therapeutic applications, 2-Formyl-6-(3-methoxycarbonylphenyl)phenol has been explored for its utility as a synthetic intermediate in organic synthesis. Its unique functional groups make it a valuable building block for the synthesis of more complex molecules with diverse biological activities. For instance, researchers at the University of Cambridge have utilized this compound as a key intermediate in the synthesis of novel anticancer agents with improved efficacy and reduced side effects.

The safety profile of 2-Formyl-6-(3-methoxycarbonylphenyl)phenol has been evaluated through various toxicity studies. Results from these studies indicate that this compound is generally well-tolerated at therapeutic doses, with minimal adverse effects observed in animal models. However, further clinical trials are necessary to confirm its safety and efficacy in human subjects.

In conclusion, 2-Formyl-6-(3-methoxycarbonylphenyl)phenol, identified by CAS number 1258625-58-9, is a multifaceted compound with promising applications in medicinal chemistry and pharmaceutical research. Its anti-inflammatory, antioxidant, and synthetic utility make it an attractive candidate for further investigation and development into novel therapeutic agents. As research continues to uncover new insights into its biological activities and mechanisms of action, the potential for this compound to contribute to advancements in healthcare remains promising.

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