Cas no 1256790-93-8 (Methyl 4-bromo-6-chloronicotinate)
Methyl 4-bromo-6-chloronicotinate is a halogenated nicotinate ester widely used as a key intermediate in pharmaceutical and agrochemical synthesis. Its distinct substitution pattern, featuring bromine and chlorine at the 4- and 6-positions of the pyridine ring, enhances reactivity for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings. The methyl ester group provides stability while allowing further functionalization via hydrolysis or transesterification. This compound is valued for its high purity, consistent performance in heterocyclic chemistry, and utility in constructing complex molecular frameworks. Its compatibility with diverse reaction conditions makes it a versatile building block for researchers developing active ingredients or specialty chemicals.
1256790-93-8 structure
Product Name:Methyl 4-bromo-6-chloronicotinate
CAS No:1256790-93-8
MF:C7H5BrClNO2
MW:250.477100133896
MDL:MFCD18257867
CID:2854664
PubChem ID:72943182
Update Time:2025-10-29
Methyl 4-bromo-6-chloronicotinate Chemical and Physical Properties
Names and Identifiers
-
- methyl 4-bromo-6-chloropyridine-3-carboxylate
- Methyl 4-broMo-6-chloronicotinate
- AMY10132
- AKOS027339750
- F11974
- methyl4-bromo-6-chloronicotinate
- CS-0040505
- DB-130147
- 1256790-93-8
- MFCD18257867
- CS-13278
- Methyl 4-bromo-6-chloronicotinate
-
- MDL： MFCD18257867
- Inchi： 1S/C7H5BrClNO2/c1-12-7(11)4-3-10-6(9)2-5(4)8/h2-3H,1H3
- InChI Key： SZKLPBKPIATTIK-UHFFFAOYSA-N
- SMILES： BrC1C=C(N=CC=1C(=O)OC)Cl
Computed Properties
- Exact Mass: 248.91922 g/mol
- Monoisotopic Mass: 248.91922 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 179
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.4
- Topological Polar Surface Area: 39.2
- Molecular Weight: 250.48
Experimental Properties
- Density: 1.684±0.06 g/cm3 (20 oC 760 Torr),
- Boiling Point: 281.3±35.0 oC (760 Torr),
- Flash Point: 123.9±25.9 oC,
- Solubility: Slightly soluble (2.3 g/l) (25 o C),
Methyl 4-bromo-6-chloronicotinate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029013793-250mg |
Methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 95% | 250mg |
$1058.40 | 2023-09-03 | |
| Alichem | A029013793-1g |
Methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 95% | 1g |
$3039.75 | 2023-09-03 | |
| Chemenu | CM325475-1g |
methyl 4-bromo-6-chloropyridine-3-carboxylate |
1256790-93-8 | 95%+ | 1g |
$808 | 2022-06-13 | |
| Chemenu | CM325475-5g |
methyl 4-bromo-6-chloropyridine-3-carboxylate |
1256790-93-8 | 95%+ | 5g |
$2434 | 2022-06-13 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB04060-5g |
methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 95% | 5g |
$1129 | 2023-09-07 | |
| eNovation Chemicals LLC | Y0995944-5g |
methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 95% | 5g |
$850 | 2024-08-02 | |
| Chemenu | CM325475-5g |
methyl 4-bromo-6-chloropyridine-3-carboxylate |
1256790-93-8 | 95%+ | 5g |
$2429 | 2021-08-18 | |
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB04060-10g |
methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 95% | 10g |
$1920 | 2023-09-07 | |
| Aaron | AR009HLS-100mg |
Methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 98% | 100mg |
$38.00 | 2025-02-10 | |
| Aaron | AR009HLS-250mg |
Methyl 4-bromo-6-chloronicotinate |
1256790-93-8 | 98% | 250mg |
$63.00 | 2025-02-10 |
Methyl 4-bromo-6-chloronicotinate Related Literature
-
Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
-
Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
-
Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
-
Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409
-
Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
1256790-93-8 (Methyl 4-bromo-6-chloronicotinate) Related Products
- 73781-91-6(methyl 6-chloropyridine-3-carboxylate)
- 1043419-29-9(METHYL 4-BROMONICOTINATE)
- 1060805-68-6(4-Bromo-2-chloronicotinic acid)
- 1064678-14-3(Methyl 4-Bromo-2-Chloronicotinate)
- 886365-28-2(Methyl 5-bromo-2-chloroisonicotinate)
- 1256834-13-5(4-broMo-6-chloronicotinic acid)
- 1214346-11-8(Ethyl 5-bromo-2-chloroisonicotinate)
- 1421621-12-6(Ethyl 4-bromo-2-chloronicotinate)
- 1214335-05-3(Methyl 2-bromo-6-chloronicotinate)
- 1060805-64-2(4-bromo-6-chloro-pyridine-3-carbaldehyde)
Recommended suppliers
TAIXING JOXIN BIO-TEC CO.,LTD.
Gold Member
Audited Supplier
CN Supplier
Bulk
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Reagent
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Reagent
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
