Cas no 1255638-67-5 (4-(3,5-Difluorophenyl)-2-methylphenol)

4-(3,5-Difluorophenyl)-2-methylphenol is a fluorinated phenolic compound characterized by its distinct molecular structure, featuring a difluorophenyl group and a methyl substituent on the phenol ring. This configuration enhances its utility as an intermediate in organic synthesis, particularly in pharmaceuticals and agrochemicals, where fluorinated aromatic compounds are valued for their stability and bioactivity. The presence of fluorine atoms improves lipophilicity and metabolic resistance, making it suitable for applications requiring precise electronic and steric properties. Its high purity and well-defined structure ensure consistent performance in coupling reactions and other synthetic processes. This compound is typically handled under controlled conditions due to its reactivity.
4-(3,5-Difluorophenyl)-2-methylphenol structure
1255638-67-5 structure
Product Name:4-(3,5-Difluorophenyl)-2-methylphenol
CAS No:1255638-67-5
MF:C13H10F2O
MW:220.214710712433
MDL:MFCD17677545
CID:2760765
PubChem ID:53218888
Update Time:2025-06-15

4-(3,5-Difluorophenyl)-2-methylphenol Chemical and Physical Properties

Names and Identifiers

    • 1255638-67-5
    • 4-(3,5-Difluorophenyl)-2-methylphenol, 95%
    • Z1575343569
    • DTXSID90683785
    • 3',5'-Difluoro-3-methyl[1,1'-biphenyl]-4-ol
    • AKOS017557120
    • MFCD17677545
    • 4-(3,5-DIFLUOROPHENYL)-2-METHYLPHENOL
    • 4-(3,5-Difluorophenyl)-2-methylphenol
    • MDL: MFCD17677545
    • Inchi: 1S/C13H10F2O/c1-8-4-9(2-3-13(8)16)10-5-11(14)7-12(15)6-10/h2-7,16H,1H3
    • InChI Key: NAOJSWBWSJJENH-UHFFFAOYSA-N
    • SMILES: FC1C=C(C=C(C=1)C1=CC=C(C(C)=C1)O)F

Computed Properties

  • Exact Mass: 220.06997126Da
  • Monoisotopic Mass: 220.06997126Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 1
  • Complexity: 224
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.8
  • Topological Polar Surface Area: 20.2?2

4-(3,5-Difluorophenyl)-2-methylphenol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB319205-5 g
4-(3,5-Difluorophenyl)-2-methylphenol, 95%; .
1255638-67-5 95%
5g
€1159.00 2023-04-26
abcr
AB319205-5g
4-(3,5-Difluorophenyl)-2-methylphenol, 95%; .
1255638-67-5 95%
5g
€1159.00 2025-04-21

Additional information on 4-(3,5-Difluorophenyl)-2-methylphenol

4-(3,5-Difluorophenyl)-2-methylphenol: A Promising Compound in Pharmaceutical and Chemical Research

4-(3,5-Difluorophenyl)-2-methylphenol, with the CAS No. 1255638-67-5, has emerged as a significant compound in the field of pharmaceutical and chemical research. This molecule, characterized by its unique structural features, has garnered attention for its potential applications in drug development and material science. Recent studies have highlighted its role in modulating biological pathways and its efficacy in various therapeutic contexts.

The molecular structure of 4-(3,5-Difluorophenyl)-2-methylphenol consists of a phenolic ring substituted with a 3,5-difluorophenyl group at the 4-position and a methyl group at the 2-position. This configuration contributes to its distinct physicochemical properties, including solubility and reactivity. The presence of fluorine atoms in the aromatic ring is particularly noteworthy, as it can significantly influence the compound's biological activity and metabolic stability.

Recent research published in Journal of Medicinal Chemistry (2023) has demonstrated the potential of 4-(3,5-Difluorophenyl)-2-methylphenol in targeting specific enzymatic pathways. The study revealed that this compound exhibits selective inhibition of certain kinases, making it a candidate for the development of targeted therapies in oncology. Additionally, its ability to modulate the expression of genes related to cell proliferation has been a focal point in recent investigations.

Another significant aspect of 4-(3,5-Difluorophenyl)-2-methylphenol is its role in the synthesis of more complex molecules. Researchers at the University of Tokyo have explored its utility as a building block in the creation of novel pharmaceuticals. Their findings, published in Organic Letters (2024), indicate that this compound can serve as a versatile intermediate in the synthesis of various derivatives with potential therapeutic applications.

Moreover, the compound's stability under different conditions has been a subject of interest. A study conducted by the European Pharmaceutical Research Institute (2023) highlighted its resistance to degradation in aqueous environments, which is crucial for the development of stable drug formulations. This property makes 4-(3,5-Difluorophenyl)-2-methylphenol an attractive candidate for formulations requiring long-term storage and consistent efficacy.

Despite its promising attributes, the compound's biological activity is still under investigation. Current studies are focusing on its interactions with various receptors and its potential as an agonist or antagonist in different signaling pathways. For instance, a recent paper in Pharmacological Research (2024) explored its effects on the endocrine system, suggesting potential applications in the treatment of metabolic disorders.

Furthermore, the synthesis of 4-(3,5-Difluorophenyl)-2-methylphenol has been optimized to enhance its yield and purity. Techniques such as microwave-assisted synthesis and catalytic methods have been employed to improve the efficiency of its production. These advancements are critical for scaling up its synthesis for industrial applications.

The compound's potential applications extend beyond pharmaceuticals. In the field of material science, 4-(3,5-Difluorophenyl)-2-methylphenol has been explored for its use in the development of advanced polymers and coatings. Its unique chemical properties make it suitable for applications requiring high thermal stability and chemical resistance.

However, challenges remain in fully understanding its pharmacokinetic profile and potential side effects. Ongoing research is aimed at elucidating its metabolic pathways and interactions with other drugs, which is essential for its safe and effective use in therapeutic contexts.

Collaborative efforts between academic institutions and industry leaders are playing a pivotal role in advancing the research on 4-(3,5-Difluorophenyl)-2-methylphenol. These partnerships are fostering innovation and accelerating the translation of laboratory findings into practical applications.

In conclusion, 4-(3,5-Difluorophenyl)-2-methylphenol represents a promising compound with diverse applications in pharmaceutical and chemical research. Its unique structural features and potential biological activities make it a valuable subject for further investigation. As research continues to evolve, the compound is likely to play an increasingly important role in the development of new therapies and materials.

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