Cas no 1225776-38-4 (4-fluoro-2-(3-hydroxyphenyl)phenol)

4-Fluoro-2-(3-hydroxyphenyl)phenol is a fluorinated phenolic compound characterized by its distinct molecular structure, incorporating both hydroxyl and fluoro substituents on aromatic rings. This configuration imparts unique electronic and steric properties, making it a valuable intermediate in organic synthesis, particularly for pharmaceuticals and advanced materials. The presence of fluorine enhances stability and influences binding interactions, while the hydroxyl groups offer sites for further functionalization. Its precise structure allows for tailored reactivity in cross-coupling reactions or as a building block for bioactive molecules. The compound's purity and defined stereochemistry ensure reproducibility in research and industrial applications.
4-fluoro-2-(3-hydroxyphenyl)phenol structure
1225776-38-4 structure
Product Name:4-fluoro-2-(3-hydroxyphenyl)phenol
CAS No:1225776-38-4
MF:C12H9FO2
MW:204.197067022324
MDL:MFCD16484047
CID:1214210
PubChem ID:52983971
Update Time:2025-10-20

4-fluoro-2-(3-hydroxyphenyl)phenol Chemical and Physical Properties

Names and Identifiers

    • 4-fluoro-2-(3-hydroxyphenyl)phenol
    • DTXSID70680777
    • 3-(5-FLUORO-2-HYDROXYPHENYL)PHENOL
    • 3-(5-Fluoro-2-hydroxyphenyl)phenol, 95%
    • 5-Fluoro[1,1'-biphenyl]-2,3'-diol
    • MFCD16484047
    • 1225776-38-4
    • MDL: MFCD16484047
    • Inchi: 1S/C12H9FO2/c13-9-4-5-12(15)11(7-9)8-2-1-3-10(14)6-8/h1-7,14-15H
    • InChI Key: ASXOEPRKGWHCAM-UHFFFAOYSA-N
    • SMILES: FC1C=CC(=C(C=1)C1C=CC=C(C=1)O)O

Computed Properties

  • Exact Mass: 204.05865769g/mol
  • Monoisotopic Mass: 204.05865769g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 210
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.3
  • Topological Polar Surface Area: 40.5?2

4-fluoro-2-(3-hydroxyphenyl)phenol Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
abcr
AB318719-5 g
3-(5-Fluoro-2-hydroxyphenyl)phenol, 95%; .
1225776-38-4 95%
5g
€1,159.00 2022-08-31
abcr
AB318719-5g
3-(5-Fluoro-2-hydroxyphenyl)phenol, 95%; .
1225776-38-4 95%
5g
€1159.00 2025-04-21

Additional information on 4-fluoro-2-(3-hydroxyphenyl)phenol

Comprehensive Analysis of 4-fluoro-2-(3-hydroxyphenyl)phenol (CAS No. 1225776-38-4): Properties, Applications, and Industry Insights

In the realm of specialty chemicals, 4-fluoro-2-(3-hydroxyphenyl)phenol (CAS No. 1225776-38-4) has garnered significant attention due to its unique molecular structure and versatile applications. This fluorinated phenolic compound, characterized by its hydroxyphenyl and fluoro substituents, is increasingly studied for its potential in pharmaceuticals, agrochemicals, and advanced material synthesis. Researchers and industry professionals frequently search for terms like "4-fluoro-2-(3-hydroxyphenyl)phenol synthesis", "CAS 1225776-38-4 applications", and "fluorophenol derivatives", reflecting growing interest in its properties and commercial viability.

The compound’s structural features, including its hydrogen-bonding capacity and electron-withdrawing fluorine, make it a valuable intermediate in drug discovery. Recent studies highlight its role in designing kinase inhibitors and antimicrobial agents, aligning with the pharmaceutical industry’s focus on targeted therapies. Environmental concerns have also driven searches for "biodegradable fluorophenols" and "green synthesis of 1225776-38-4", emphasizing the demand for sustainable production methods. Analytical techniques such as HPLC and NMR are critical for quality control, as purity thresholds often exceed 98% for research-grade batches.

From a material science perspective, 4-fluoro-2-(3-hydroxyphenyl)phenol serves as a precursor for high-performance polymers. Its ability to enhance thermal stability and chemical resistance resonates with trends in electronic encapsulation materials and flame-retardant additives. Patent analyses reveal a surge in filings related to its use in OLED manufacturing, particularly for electron-transport layers. This aligns with the global push toward energy-efficient displays, a topic dominating tech forums and R&D pipelines.

Regulatory compliance remains a key consideration, with databases like REACH and PubChem providing updated safety profiles. While not classified as hazardous under current guidelines, proper handling protocols for fluorinated aromatics are widely discussed in industrial hygiene circles. The compound’s logP value and photostability data are frequently queried by formulation scientists optimizing delivery systems, underscoring its multidisciplinary relevance.

Market projections suggest steady growth for CAS 1225776-38-4, driven by Asia-Pacific’s expanding pharmaceutical sector. Competitor benchmarks indicate pricing volatility due to limited suppliers, prompting interest in alternate synthetic routes. Academic collaborations are exploring catalytic fluorination methods to reduce production costs—a hot topic in process chemistry webinars. As sustainability metrics gain traction, life-cycle assessments of such intermediates will likely influence procurement strategies.

In summary, 4-fluoro-2-(3-hydroxyphenyl)phenol exemplifies the convergence of innovation and practicality in modern chemistry. Its dual functionality as a pharmacophore and material building block positions it at the forefront of multiple industries, with research momentum showing no signs of slowing. For laboratories and manufacturers, staying abreast of its evolving applications—from bioconjugation techniques to polymeric nanocomposites—is essential to leverage its full potential.

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