Cas no 1255206-72-4 (6-Bromo-3-hydroxy-2-methylbenzyl alcohol)
6-Bromo-3-hydroxy-2-methylbenzyl alcohol Chemical and Physical Properties
Names and Identifiers
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- 4-bromo-3-(hydroxymethyl)-2-methylphenol
- PCIBNCRQRIUZMN-UHFFFAOYSA-N
- 4-bromo-3-hydroxymethyl-2-methyl phenol
- 6-Bromo-3-hydroxy-2-methylbenzyl alcohol
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- Inchi: 1S/C8H9BrO2/c1-5-6(4-10)7(9)2-3-8(5)11/h2-3,10-11H,4H2,1H3
- InChI Key: PCIBNCRQRIUZMN-UHFFFAOYSA-N
- SMILES: BrC1=CC=C(C(C)=C1CO)O
Computed Properties
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 129
- Topological Polar Surface Area: 40.5
6-Bromo-3-hydroxy-2-methylbenzyl alcohol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A019147058-1g |
4-Bromo-3-(hydroxymethyl)-2-methylphenol |
1255206-72-4 | 95% | 1g |
$998.00 | 2023-09-03 | |
| TRC | B013082-250mg |
6-Bromo-3-hydroxy-2-methylbenzyl alcohol |
1255206-72-4 | 250mg |
$ 565.00 | 2022-06-07 | ||
| TRC | B013082-500mg |
6-Bromo-3-hydroxy-2-methylbenzyl alcohol |
1255206-72-4 | 500mg |
$ 940.00 | 2022-06-07 | ||
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1201613-1g |
4-Bromo-3-(hydroxymethyl)-2-methylphenol |
1255206-72-4 | 95% | 1g |
¥5448.00 | 2024-08-09 | |
| A2B Chem LLC | AA30653-1g |
4-Bromo-3-(hydroxymethyl)-2-methylphenol |
1255206-72-4 | 95% | 1g |
$677.00 | 2024-04-20 | |
| A2B Chem LLC | AA30653-5g |
4-Bromo-3-(hydroxymethyl)-2-methylphenol |
1255206-72-4 | 95% | 5g |
$1203.00 | 2024-04-20 |
6-Bromo-3-hydroxy-2-methylbenzyl alcohol Related Literature
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J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
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Li-Hua Gan,Rui Wu,Jian-Lei Tian,Patrick W. Fowler Phys. Chem. Chem. Phys., 2017,19, 419-425
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Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
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Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
Additional information on 6-Bromo-3-hydroxy-2-methylbenzyl alcohol
Introduction to 6-Bromo-3-hydroxy-2-methylbenzyl Alcohol (CAS No. 1255206-72-4)
6-Bromo-3-hydroxy-2-methylbenzyl alcohol is a significant compound in the field of pharmaceutical chemistry, characterized by its unique structural and functional properties. This compound, identified by the CAS number 1255206-72-4, has garnered considerable attention due to its potential applications in drug development and synthetic chemistry. The presence of both bromine and hydroxyl functional groups, along with a methyl substituent, makes it a versatile intermediate for various chemical transformations.
The< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol molecule exhibits a benzylic alcohol backbone, which is a common motif in many bioactive molecules. The bromine atom at the sixth position and the hydroxyl group at the third position introduce reactivity that can be exploited in synthetic pathways. This combination allows for further functionalization through nucleophilic aromatic substitution, cross-coupling reactions, and other organic transformations, making it a valuable building block in medicinal chemistry.
In recent years, there has been growing interest in the development of novel pharmaceuticals that target complex biological pathways. The< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol compound has been explored in several research studies for its potential role in synthesizing molecules with therapeutic properties. For instance, its structure resembles certain natural products known for their biological activity, suggesting that derivatives of this compound could have similar effects on biological targets.
One of the most promising applications of< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol is in the synthesis of kinase inhibitors. Kinases are enzymes that play a crucial role in cell signaling pathways and are often implicated in diseases such as cancer. By modifying the< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol scaffold, researchers have been able to develop molecules that selectively inhibit specific kinases, thereby offering potential treatments for these diseases. The bromine atom provides a handle for further derivatization, allowing chemists to fine-tune the properties of these inhibitors.
The hydroxyl group in< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol also contributes to its versatility. Hydroxyl groups can participate in hydrogen bonding interactions, which are critical for the binding affinity of drug candidates to their target proteins. Additionally, they can be oxidized to form aldehydes or carboxylic acids, expanding the range of possible synthetic routes. These features make< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol an attractive starting point for designing new drugs.
In addition to its pharmaceutical applications, 6-bromo-3-hydroxy-2-methylbenzyl alcohol has found utility in materials science and industrial chemistry. Its unique reactivity allows it to be incorporated into polymers and other materials, enhancing their properties through cross-linking or other chemical modifications. This broadens its applicability beyond traditional drug discovery and into areas such as advanced materials development.
The synthesis of< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol itself is an intriguing process that highlights its synthetic value. One common approach involves the bromination of a methyl-substituted benzene ring followed by selective hydroxylation. These steps showcase the compound's ability to undergo multiple functionalization reactions while maintaining structural integrity. The yields and efficiencies of these reactions can be optimized using various catalysts and reaction conditions, making large-scale production feasible.
The growing body of research on< strong>6-bromo-3-hydroxy-2-methylbenzyl alcohol underscores its importance as a chemical intermediate. As new methodologies emerge in synthetic chemistry, the potential applications of this compound are likely to expand further. Researchers continue to explore novel derivatives and reaction pathways that could unlock even more possibilities for this versatile molecule.
In conclusion, 6-bromo-3-hydroxy-2-methylbenzyl alcohol (CAS No. 1255206-72-4) is a compound with significant potential across multiple domains of chemistry and biology. Its unique structural features make it an invaluable tool for drug development, materials science, and industrial applications. As research progresses, we can expect to see even more innovative uses for this remarkable molecule.
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