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  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 2. Distinction of trans–cis photoisomers with comparable optical properties in multiple-state photochromic systems – examining a molecule with three azobenzenes via in situ irradiation NMR spectroscopy?
  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
• 3. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolidines Pyrrolidines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyrrolidines

Introduction to N-methyl-N-(propan-2-yl)pyrrolidin-3-amine (CAS No. 1247394-67-7)

N-methyl-N-(propan-2-yl)pyrrolidin-3-amine, a compound with the chemical formula C₉H₁₇N, is a significant molecule in the field of pharmaceutical chemistry. This compound is characterized by its N-methyl-N-(propan-2-yl)pyrrolidin-3-amine structure, which makes it a valuable intermediate in the synthesis of various bioactive molecules. With a CAS number of 1247394-67-7, this compound has garnered attention due to its potential applications in medicinal chemistry and drug development.

The pyrrolidin core of N-methyl-N-(propan-2-yl)pyrrolidin-3-amine is a common motif in many pharmacologically active agents. Pyrrolidine derivatives are known for their versatility in drug design, often serving as key structural elements in small molecule drugs. The presence of the methyl and isopropyl substituents in this compound enhances its complexity and reactivity, making it a promising candidate for further chemical modifications.

In recent years, there has been a growing interest in the development of novel therapeutic agents that target specific biological pathways. N-methyl-N-(propan-2-yl)pyrrolidin-3-amine has been explored as a potential scaffold for drugs targeting neurological disorders, including depression and anxiety. Its structural features allow for interactions with various neurotransmitter receptors, making it a candidate for the development of next-generation psychotropic medications.

One of the most compelling aspects of N-methyl-N-(propan-2-yl)pyrrolidin-3-amine is its role in the synthesis of more complex molecules. Researchers have utilized this compound as a building block to create derivatives with enhanced pharmacological properties. For instance, modifications to the N-methyl-N-(propan-2-yl)pyrrolidin-3-amine core have led to the discovery of compounds with improved solubility, bioavailability, and target specificity.

The pharmaceutical industry has been particularly interested in pyrrolidine derivatives due to their ability to modulate various biological processes. N-methyl-N-(propan-2-yl)pyrrolidin-3-amine has been studied for its potential to interact with enzymes and receptors involved in pain perception, inflammation, and neurotransmission. These interactions are crucial for developing drugs that can effectively treat a wide range of conditions.

Recent advancements in computational chemistry have enabled researchers to predict the binding affinities and pharmacokinetic profiles of molecules like N-methyl-N-(propan-2-yl)pyrrolidin-3-amine with greater accuracy. These computational tools have helped streamline the drug discovery process by identifying promising candidates for further experimental validation. The integration of machine learning algorithms has further enhanced the ability to design molecules with specific therapeutic properties.

The synthesis of N-methyl-N-(propan-2-y l)pyrrolidin -3 -amine involves multi-step organic reactions that require careful optimization. The process typically begins with the formation of the pyrrolidine ring, followed by functional group transformations to introduce the methyl and isopropyl substituents. Advanced synthetic techniques, such as catalytic hydrogenation and cross-coupling reactions, have been employed to achieve high yields and purity levels.

In addition to its pharmaceutical applications, N-methyl-N-(propan -2 -y l)py rrolidin -3 -amine has shown promise in materials science. Its unique structural features make it a suitable candidate for developing novel polymers and coatings with enhanced mechanical and thermal properties. The compound's ability to form stable complexes with other molecules also opens up possibilities for applications in catalysis and nanotechnology.

The safety and regulatory aspects of working with N-methyl-N-(propan -2 -y l)py rrolidin -3 -amine are critical considerations for researchers and manufacturers. While this compound is not classified as a hazardous material, proper handling procedures must be followed to ensure worker safety and environmental protection. Detailed protocols for storage, handling, and disposal have been established to minimize risks associated with its use.

The future prospects of N-methyl-N-(propan -2 -y l)py rrolidin -3 -amine are promising, given its diverse applications and potential for further innovation. As research continues to uncover new therapeutic targets and synthetic methodologies, this compound is likely to play an increasingly important role in drug development and materials science. Collaborative efforts between academia and industry will be essential to fully realize its potential.

• 900164-95-6(1-[(3R)-pyrrolidin-3-yl]pyrrolidine)
• 132883-44-4((3S)-N,N-dimethylpyrrolidin-3-amine)
• 132958-72-6((3R)-N,N-dimethylpyrrolidin-3-amine)
• 20984-81-0(N,N-diethylpyrrolidin-3-amine)
• 169750-78-1(3-Pyrrolidinamine,N-ethyl-N-methyl-,(S)-(9CI))
• 64021-83-6(N,1-Dimethylpyrrolidin-3-amine)
• 267241-99-6(1,3'-bipyrrolidine)
• 859282-12-5((3S)-3-(pyrrolidin-1-yl)pyrrolidine)
• 69478-75-7(N,N-Dimethylpyrrolidin-3-amine)
• 503067-85-4(N-methyl-1-(propan-2-yl)pyrrolidin-3-amine)