• 1. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 2. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
• 3. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 4. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 5. Evidence of rutile-to-anatase photo-induced electron transfer in mixed-phase TiO2 by solid-state NMR spectroscopy?
  Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

Boc-D-tert-leucine (CAS No. 124655-17-0): A Comprehensive Guide to Its Properties and Applications

Boc-D-tert-leucine (CAS No. 124655-17-0) is a specialized amino acid derivative widely used in peptide synthesis and pharmaceutical research. This compound, known for its unique steric hindrance due to the tert-butyl group, plays a pivotal role in the development of bioactive peptides and drug candidates. Researchers and pharmaceutical companies frequently search for "Boc-D-tert-leucine uses" or "CAS 124655-17-0 suppliers," highlighting its importance in modern chemistry.

The chemical structure of Boc-D-tert-leucine features a Boc (tert-butoxycarbonyl) protecting group, which is crucial for selective peptide bond formation. This makes it a preferred choice for solid-phase peptide synthesis (SPPS), a technique gaining traction due to the rising demand for peptide-based therapeutics. With increasing interest in "peptide drug discovery" and "custom peptide synthesis," this compound has become a hot topic in academic and industrial labs.

One of the standout properties of Boc-D-tert-leucine is its ability to enhance the stability and bioavailability of synthetic peptides. This aligns with current trends in "targeted drug delivery" and "biostable peptide design," where researchers seek compounds that resist enzymatic degradation. The D-configuration of this amino acid derivative further expands its utility in creating peptidomimetics, a growing field in medicinal chemistry.

In the market, Boc-D-tert-leucine is often compared to other N-protected amino acids, such as Fmoc derivatives. However, its tert-leucine backbone offers distinct advantages, including improved solubility in organic solvents—a key factor for large-scale peptide production. Suppliers and manufacturers frequently highlight its "high purity grade" and "GMP-compliant synthesis" to meet the stringent requirements of pharmaceutical applications.

Recent advancements in "green chemistry" have also impacted the production of Boc-D-tert-leucine. Environmentally friendly synthesis methods, such as catalytic protection strategies, are now being explored to reduce waste and improve yield. This resonates with the global push for "sustainable chemical manufacturing"—a frequently searched term among environmentally conscious researchers.

For those wondering "where to buy Boc-D-tert-leucine," it’s essential to consider vendors who provide detailed COA (Certificate of Analysis) and MSDS documentation. The compound’s shelf life and storage conditions (typically 2-8°C under inert atmosphere) are critical for maintaining its reactivity in peptide coupling reactions. These practical aspects are often overlooked in "amino acid purchasing guides," making them valuable insights for first-time buyers.

The versatility of Boc-D-tert-leucine extends beyond pharmaceuticals. It’s increasingly used in materials science for designing peptide-based hydrogels and bioinspired polymers—areas gaining attention in "soft robotics" and "tissue engineering" research. Its chiral purity (>99%) makes it indispensable for asymmetric synthesis, another trending topic in organic chemistry forums.

In summary, Boc-D-tert-leucine (CAS No. 124655-17-0) bridges multiple cutting-edge scientific disciplines. From answering "how to use Boc-protected amino acids" to addressing "peptide stability challenges," this compound remains at the forefront of chemical innovation. As research continues to explore its potential, its role in next-generation therapeutics and advanced materials is set to expand further.

• 153568-33-3(Boc-L-Valine-d)
• 54895-12-4(2-((tert-Butoxycarbonyl)amino)-3-methylbutanoic acid)
• 141509-91-3(L-Valine-15N,N-[(1,1-dimethylethoxy)carbonyl]- (9CI))
• 22838-58-0(tert-Butoxycarbonyl-D-valine)
• 62965-35-9(N-Boc-L-tert-Leucine)
• 140923-27-9((S)-2-((Isopropoxycarbonyl)amino)-3-methylbutanoic acid)
• 169870-82-0(N-boc-tert-Butylglycine)
• 89536-85-6((R)-2-((tert-Butoxycarbonyl)(methyl)amino)-3-methylbutanoic acid)
• 361441-97-6((2S)-2-(adamantan-1-yl)-2-{[(tert-butoxy)carbonyl]amino}acetic acid)
• 13734-41-3(Boc-L-Valine)