Cas no 1233958-26-3 (Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate)

Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate structure
1233958-26-3 structure
Product Name:Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate
CAS No:1233958-26-3
MF:C16H25N3O4S
MW:355.452402830124
CID:4788497
Update Time:2025-11-02

Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate
    • Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate
    • Inchi: 1S/C16H25N3O4S/c1-16(2,3)23-15(20)19-10-8-12(9-11-19)18-24(21,22)14-7-5-4-6-13(14)17/h4-7,12,18H,8-11,17H2,1-3H3
    • InChI Key: ZXNLMYWIWPCWAM-UHFFFAOYSA-N
    • SMILES: S(C1C=CC=CC=1N)(NC1CCN(C(=O)OC(C)(C)C)CC1)(=O)=O

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 5
  • Complexity: 531
  • XLogP3: 2.2
  • Topological Polar Surface Area: 110

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Additional information on Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate

Comprehensive Overview of Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate (CAS No. 1233958-26-3)

The compound Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate (CAS No. 1233958-26-3) is a specialized organic molecule that has garnered significant attention in pharmaceutical and chemical research. This piperidine derivative is characterized by its unique sulfonamido and tert-butyl carboxylate functional groups, which contribute to its versatility in drug discovery and development. Researchers are particularly interested in its potential applications as a building block for bioactive molecules, given its structural complexity and functional group compatibility.

In recent years, the demand for high-purity intermediates like Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate has surged, driven by advancements in medicinal chemistry and small-molecule therapeutics. The compound’s CAS number 1233958-26-3 is frequently searched in academic and industrial databases, reflecting its relevance in cutting-edge research. Its synthetic utility lies in its ability to serve as a precursor for heterocyclic compounds, which are pivotal in designing kinase inhibitors and GPCR-targeted drugs.

One of the trending topics in the scientific community is the exploration of sulfonamide-based compounds for their antibacterial and anti-inflammatory properties. Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate aligns with this research focus, as its sulfonamido moiety may offer synergistic effects in drug design. Additionally, its piperidine scaffold is a common feature in CNS-active drugs, making it a candidate for neurological disorder treatments.

The compound’s chemical stability and solubility profile are also critical factors for its adoption in high-throughput screening (HTS) assays. Researchers often inquire about its storage conditions, handling protocols, and compatibility with common reagents, underscoring its practical importance in laboratory settings. Furthermore, its regioselective reactivity enables precise modifications, which are essential for structure-activity relationship (SAR) studies.

From an SEO perspective, queries such as "CAS 1233958-26-3 supplier," "Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate synthesis," and "piperidine derivatives in drug discovery" highlight the compound’s commercial and academic appeal. Its inclusion in patent literature and research publications further validates its significance. As the pharmaceutical industry shifts toward personalized medicine, intermediates like this are poised to play a pivotal role in tailored therapeutic solutions.

In summary, Tert-Butyl 4-(2-aminophenylsulfonamido)piperidine-1-carboxylate (CAS No. 1233958-26-3) represents a critical chemical entity with broad applications in drug development and material science. Its structural features and functional diversity make it a valuable asset for researchers aiming to address unmet medical needs. As innovation in organic synthesis continues to evolve, this compound is likely to remain a focal point in both industrial and academic circles.

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