Production Method 1

1233921-74-8

1233921-81-7

1233921-83-9

1233921-85-1

Reaction Conditions

1.1R:Proton sponge, R:POCl3, S:(MeO)3PO, 10 min, cooled; 2.5-6.5 h, rt
2.1R:S:DMF, 10 min, cooled
2.2R:H2O, S:H2O

Reference

Facile Small Scale Synthesis of Nucleoside 5'-Phosphate Mixtures

By Jansen, Robert S. et al, Nucleosides, 2010, 29(1), 14-26

Gemcitabine Monophosphate-13C,15N2 Raw materials

• 13C,15N2]-Gemcitabine

Gemcitabine Monophosphate-13C,15N2 Preparation Products

• Gemcitabine Diphosphate-13C-15N2 Tri(triethylamine) Salt (1233921-83-9)
• Gemcitabine Monophosphate-13C,15N2 (1233921-81-7)
• [13C,15N2]-Gemcitabine triphosphate (1233921-85-1)

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