Cas no 12321-44-7 (Calcitonin (swine)(9CI))

Calcitonin (swine)(9CI) is a polypeptide hormone derived from porcine sources, primarily utilized in biochemical and pharmacological research. It plays a critical role in calcium homeostasis by inhibiting osteoclast activity, thereby reducing bone resorption. This product is valued for its high purity and biological activity, making it suitable for studies involving calcium metabolism, bone disorders, and endocrine regulation. Its structural similarity to human calcitonin allows for comparative research, though species-specific differences should be noted. The product is typically supplied in lyophilized form, ensuring stability and ease of reconstitution for experimental use. Proper storage and handling are essential to maintain its integrity and functionality.
Calcitonin (swine)(9CI) structure
Calcitonin (swine)(9CI) structure
Product Name:Calcitonin (swine)(9CI)
CAS No:12321-44-7
MF:C159H234N46O45S3
MW:3606.03549051285
CID:159673
PubChem ID:16132275
Update Time:2025-11-02

Calcitonin (swine)(9CI) Chemical and Physical Properties

Names and Identifiers

    • Calcitonin (swine)(9CI)
    • Calcitonin (porcine)
    • CALCITONIN
    • H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Ser-Ala-Tyr-Trp-Arg-Asn-Leu-Asn-Asn-Phe-His-Arg-Phe-Ser-Gly-Met-Gly-Phe-Gly-Pro-Glu-Thr-Pro-NH2 (Disulfide bond)
    • PORCINE
    • CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-SER-ALA-TYR-TRP-ARG-ASN-LEU-ASN-ASN-PHE-HIS-ARG-PHE-SER-GLY-MET-GLY-PHE-GLY-PRO-GLU-THR-PRO-NH2
    • CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-SER-ALA-TYR-TRP-ARG-ASN-LEU-ASN-ASN-PHE-HIS-ARG-PHE-SER-GLY-MET-GLY-PHE-GLY-PRO-GLU-THR-PRO-NH2 (DISULFIDE BRIDGE: CYS1-CYS7)
    • ba46534
    • calcitare
    • pigcalcitonin
    • calcitonin(pig)
    • porcinecalcitonin
    • calcitonin(swine)
    • thyrocalcitonin(pig)
    • THYROCALCITONIN PORCINE
    • pigalpha-thyrocalcitonin
    • DTXSID50153898
    • NCGC00181747-01
    • 12321-44-7
    • Calcitonin, porcine
    • SCHEMBL270044
    • NS00121358
    • Inchi： 1S/C159H234N46O45S3/c1-77(2)52-98(185-146(239)107(61-118(161)213)191-136(229)95(37-25-48-172-159(168)169)181-144(237)105(59-88-65-173-93-35-23-22-34-91(88)93)189-141(234)102(58-87-40-42-90(212)43-41-87)184-130(223)81(9)178-150(243)112(71-207)198-140(233)100(54-79(5)6)195-155(248)126(80(7)8)201-153(246)115(75-252)200-156(249)127(82(10)210)202-152(245)114(73-209)199-139(232)99(53-78(3)4)186-147(240)110(64-121(164)216)194-151(244)113(72-208)196-131(224)92(160)74-251)138(231)192-109(63-120(163)215)149(242)193-108(62-119(162)214)148(241)188-103(56-85-30-18-14-19-31-85)142(235)190-106(60-89-66-170-76-177-89)145(238)182-94(36-24-47-171-158(166)167)135(228)187-104(57-86-32-20-15-21-33-86)143(236)197-111(70-206)134(227)175-67-122(217)179-97(46-51-253-12)132(225)174-68-123(218)180-101(55-84-28-16-13-17-29-84)133(226)176-69-124(219)204-49-27-39-117(204)154(247)183-96(44-45-125(220)221)137(230)203-128(83(11)211)157(250)205-50-26-38-116(205)129(165)222/h13-23,28-35,40-43,65-66,76-83,92,94-117,126-128,173,206-212,251-252H,24-27,36-39,44-64,67-75,160H2,1-12H3,(H2,161,213)(H2,162,214)(H2,163,215)(H2,164,216)(H2,165,222)(H,170,177)(H,174,225)(H,175,227)(H,176,226)(H,178,243)(H,179,217)(H,180,218)(H,181,237)(H,182,238)(H,183,247)(H,184,223)(H,185,239)(H,186,240)(H,187,228)(H,188,241)(H,189,234)(H,190,235)(H,191,229)(H,192,231)(H,193,242)(H,194,244)(H,195,248)(H,196,224)(H,197,236)(H,198,233)(H,199,232)(H,200,249)(H,201,246)(H,202,245)(H,203,230)(H,220,221)(H4,166,167,171)(H4,168,169,172)/t81-,82+,83+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,126-,127-,128-/m0/s1
    • InChI Key： FMPTWBWKJAJGSR-LJNLPFSOSA-N
    • SMILES： S(C)CC[C@@H](C(NCC(N[C@@H](CC1C=CC=CC=1)C(NCC(N1CCC[C@H]1C(N[C@@H](CCC(=O)O)C(N[C@@H]([C@@H](C)O)C(N1CCC[C@H]1C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC(CNC([C@H](CO)NC([C@H](CC1C=CC=CC=1)NC([C@H](CCCNC(=N)N)NC([C@H](CC1=CN=CN1)NC([C@H](CC1C=CC=CC=1)NC([C@H](CC(N)=O)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(=N)N)NC([C@H](CC1=CNC2C=CC=CC1=2)NC([C@H](CC1C=CC(=CC=1)O)NC([C@H](C)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](CS)NC([C@H]([C@@H](C)O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](CO)NC([C@H](CS)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Computed Properties

  • Exact Mass: 3601.64596
  • Monoisotopic Mass: 3603.659832
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 53
  • Hydrogen Bond Acceptor Count: 52
  • Heavy Atom Count: 253
  • Rotatable Bond Count: 112
  • Complexity: 8530
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 31
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 1000
  • XLogP3: -12.9
  • Topological Polar Surface Area: 1500

Experimental Properties

  • PSA: 1467.37

Calcitonin (swine)(9CI) Security Information

  • WGK Germany：3
  • RTECS：XP3561000
  • Storage Condition：?20°C

Calcitonin (swine)(9CI) Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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Calcitonin (swine)(9CI) Related Literature

Additional information on Calcitonin (swine)(9CI)

Comprehensive Guide to Calcitonin (swine)(9CI) (CAS No. 12321-44-7): Properties, Applications, and Market Insights

Calcitonin (swine)(9CI) (CAS No. 12321-44-7) is a biologically active peptide hormone derived from swine. This compound plays a critical role in calcium homeostasis and bone metabolism, making it a subject of significant interest in medical and pharmaceutical research. With its unique properties, Calcitonin (swine)(9CI) has been widely studied for its therapeutic potential in conditions such as osteoporosis, Paget's disease, and hypercalcemia.

The molecular structure of Calcitonin (swine)(9CI) consists of 32 amino acids, featuring a disulfide bridge that stabilizes its conformation. This structural integrity is essential for its biological activity, particularly in binding to the calcitonin receptor (CTR) on osteoclasts, thereby inhibiting bone resorption. Researchers often compare its efficacy with human and salmon calcitonin, highlighting its unique pharmacokinetic profile.

One of the most searched questions about Calcitonin (swine)(9CI) is its role in osteoporosis treatment. With the global rise in aging populations, osteoporosis has become a pressing health concern. Studies suggest that Calcitonin (swine)(9CI) can reduce fracture risk by up to 30% in postmenopausal women, making it a valuable alternative for patients who cannot tolerate bisphosphonates. This aligns with the growing demand for non-invasive bone therapies and personalized medicine.

Another trending topic is the use of Calcitonin (swine)(9CI) in veterinary medicine. Swine-derived calcitonin has shown promise in treating metabolic bone disorders in livestock, improving bone density and overall animal health. This application is particularly relevant as the agricultural sector seeks sustainable solutions to enhance livestock productivity.

From a market perspective, the demand for Calcitonin (swine)(9CI) is expected to grow, driven by advancements in peptide synthesis and drug delivery technologies. Innovations such as nasal sprays and transdermal patches are expanding its accessibility, addressing challenges like poor oral bioavailability. Investors and researchers are closely monitoring these developments, as they could revolutionize the treatment of bone-related disorders.

In conclusion, Calcitonin (swine)(9CI) (CAS No. 12321-44-7) remains a vital compound in both human and veterinary medicine. Its multifaceted applications, coupled with ongoing research into novel delivery methods, position it as a key player in the future of bone health management. For those seeking reliable suppliers or detailed technical data, ensuring product purity and compliance with regulatory standards is paramount.

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