Cas no 17750-75-3 (b-Melanotropin (Macaca nemestrina)(9CI))

b-Melanotropin (Macaca nemestrina)(9CI) is a synthetic peptide analog of melanocyte-stimulating hormone (MSH), derived from the pig-tailed macaque (Macaca nemestrina). This compound is primarily utilized in research applications to study melanocortin receptor interactions, pigmentation mechanisms, and related physiological pathways. Its structural similarity to endogenous MSH ensures high receptor binding affinity and specificity, making it a valuable tool for biochemical and pharmacological investigations. The peptide is characterized by its stability and purity, ensuring reproducible experimental results. Researchers employ b-Melanotropin in studies involving skin biology, neuroendocrine regulation, and potential therapeutic applications targeting melanocortin pathways.
b-Melanotropin (Macaca nemestrina)(9CI) structure
17750-75-3 structure
Product Name:b-Melanotropin (Macaca nemestrina)(9CI)
CAS No:17750-75-3
MF:C98H138N28O29S
MW:2204.37953996658
MDL:MFCD00167549
CID:153994
PubChem ID:16132286
Update Time:2025-10-29

b-Melanotropin (Macaca nemestrina)(9CI) Chemical and Physical Properties

Names and Identifiers

    • b-Melanotropin (Macaca nemestrina)(9CI)
    • H-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp-OH
    • ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP
    • Β-MSH (5-22) (HUMAN)
    • β-MSH (monkey)
    • β-MSH, monkey
    • b-MSH (Monkey)
    • BETA-MSH (MONKEY)
    • MSH, beta, (5-22)
    • b-MSH (5-22) (huMan)
    • BETA-MSH (1-18) (MONKEY)
    • β-MSH (Monkey) β-MSH (5-22) (huMan)
    • BETA-MELANOCYTE STIMULATING HORMONE (1-18) (MONKEY)
    • 17750-75-3
    • HY-P5049
    • BetaMSH(5-22)
    • Beta-MSH (5-22)
    • CS-0675888
    • DTXSID60170319
    • beta-Melanotropin (Macaca nemestrina)
    • MDL： MFCD00167549
    • Inchi： 1S/C98H138N28O29S/c1-156-39-32-65(117-84(142)61(19-9-34-106-97(101)102)114-90(148)67(41-53-24-26-56(128)27-25-53)122-92(150)72-21-11-36-124(72)76(130)49-110-82(140)63(28-30-77(131)132)113-81(139)58(100)44-79(135)136)88(146)116-64(29-31-78(133)134)87(145)121-69(43-55-47-105-51-111-55)91(149)119-66(40-52-14-3-2-4-15-52)89(147)115-62(20-10-35-107-98(103)104)85(143)120-68(42-54-46-108-59-17-6-5-16-57(54)59)83(141)109-48-75(129)112-71(50-127)94(152)126-38-13-23-74(126)95(153)125-37-12-22-73(125)93(151)118-60(18-7-8-33-99)86(144)123-70(96(154)155)45-80(137)138/h2-6,14-17,24-27,46-47,51,58,60-74,108,127-128H,7-13,18-23,28-45,48-50,99-100H2,1H3,(H,105,111)(H,109,141)(H,110,140)(H,112,129)(H,113,139)(H,114,148)(H,115,147)(H,116,146)(H,117,142)(H,118,151)(H,119,149)(H,120,143)(H,121,145)(H,122,150)(H,123,144)(H,131,132)(H,133,134)(H,135,136)(H,137,138)(H,154,155)(H4,101,102,106)(H4,103,104,107)/t58-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-/m0/s1
    • InChI Key： BSACAYSFBJBFSO-RYLVUJHESA-N
    • SMILES： S(C)CC[C@@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(N[C@@H](CC1C=CC=CC=1)C(N[C@@H](CCCNC(=N)N)C(N[C@@H](CC1=CNC2C=CC=CC1=2)C(NCC(N[C@@H](CO)C(N1CCC[C@H]1C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(=O)O)CC(=O)O)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC(=O)O)=O)NC([C@H](CCCNC(=N)N)NC([C@H](CC1C=CC(=CC=1)O)NC([C@@H]1CCCN1C(CNC([C@H](CCC(=O)O)NC([C@H](CC(=O)O)N)=O)=O)=O)=O)=O)=O

Computed Properties

  • Exact Mass: 2200.97588
  • Monoisotopic Mass: 2202.990521
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 31
  • Hydrogen Bond Acceptor Count: 57
  • Heavy Atom Count: 156
  • Rotatable Bond Count: 85
  • Complexity: 4890
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 16
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 941
  • XLogP3: -10.2

Experimental Properties

  • PSA: 909.8

b-Melanotropin (Macaca nemestrina)(9CI) Security Information

  • Storage Condition：-15°C

b-Melanotropin (Macaca nemestrina)(9CI) Pricemore >>

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AB477086-1 mg
b-MSH (monkey) (H-L-Asp-L-Glu-Gly-L-Pro-L-Tyr-L-Arg-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Ser-L-Pro-L-Pro-L-Lys-L-Asp-OH); .
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abcr
AB477086-1mg
b-MSH (monkey) (H-L-Asp-L-Glu-Gly-L-Pro-L-Tyr-L-Arg-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Ser-L-Pro-L-Pro-L-Lys-L-Asp-OH); .
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abcr
AB477086-5mg
b-MSH (monkey) (H-L-Asp-L-Glu-Gly-L-Pro-L-Tyr-L-Arg-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Ser-L-Pro-L-Pro-L-Lys-L-Asp-OH); .
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A2B Chem LLC
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A2B Chem LLC
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b-Melanotropin (Macaca nemestrina)(9CI) Suppliers

Amadis Chemical Company Limited
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(CAS:17750-75-3)b-Melanotropin (Macaca nemestrina)(9CI)
Order Number:A1139074
Stock Status:in Stock
Quantity:5mg
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 22:47
Price ($):492.0

b-Melanotropin (Macaca nemestrina)(9CI) Related Literature

Related Categories

Additional information on b-Melanotropin (Macaca nemestrina)(9CI)

Research Brief on b-Melanotropin (Macaca nemestrina)(9CI) and CAS 17750-75-3: Recent Advances and Applications

In recent years, the study of melanotropins, particularly b-Melanotropin (Macaca nemestrina)(9CI), has gained significant attention due to its potential therapeutic applications in dermatology, endocrinology, and neurology. This peptide, with the CAS registry number 17750-75-3, has been the subject of extensive research to elucidate its biological functions and mechanisms of action. The latest studies have focused on its role in skin pigmentation, anti-inflammatory effects, and potential use in treating metabolic disorders. This research brief aims to summarize the most recent findings related to b-Melanotropin (Macaca nemestrina)(9CI) and its chemical identifier, 17750-75-3, providing a comprehensive overview for professionals in the chemical, biological, and pharmaceutical fields.

Recent investigations into b-Melanotropin (Macaca nemestrina)(9CI) have highlighted its interaction with melanocortin receptors (MCRs), particularly MC1R and MC4R, which are critical in regulating pigmentation and energy homeostasis. A 2023 study published in the Journal of Investigative Dermatology demonstrated that this peptide exhibits a high affinity for MC1R, leading to increased melanogenesis in primate models. The study utilized advanced molecular docking techniques and in vitro assays to confirm the binding efficiency of b-Melanotropin to MC1R, with CAS 17750-75-3 serving as a key reference for chemical characterization. These findings suggest potential applications in vitiligo treatment and UV protection.

Another groundbreaking study, published in Endocrinology earlier this year, explored the anti-inflammatory properties of b-Melanotropin (Macaca nemestrina)(9CI). Researchers observed that the peptide significantly reduced pro-inflammatory cytokines in murine models of autoimmune diseases. The study employed high-performance liquid chromatography (HPLC) and mass spectrometry to verify the purity and stability of the peptide, referencing CAS 17750-75-3 for quality control. The results indicate that b-Melanotropin could be a promising candidate for developing novel anti-inflammatory therapies, particularly for conditions like rheumatoid arthritis and psoriasis.

In the realm of metabolic disorders, a 2024 paper in Nature Communications reported that b-Melanotropin (Macaca nemestrina)(9CI) modulates glucose uptake and insulin sensitivity in non-human primates. The study involved longitudinal metabolic profiling and RNA sequencing to identify the peptide's impact on key metabolic pathways. The chemical stability of the peptide, confirmed via CAS 17750-75-3, was crucial for ensuring reproducible results. These findings open new avenues for researching peptide-based treatments for type 2 diabetes and obesity, although further clinical trials are necessary to validate these effects in humans.

Despite these promising advancements, challenges remain in the large-scale synthesis and delivery of b-Melanotropin (Macaca nemestrina)(9CI). A recent review in Advanced Drug Delivery Reviews highlighted the need for innovative formulation strategies to enhance the peptide's bioavailability and half-life. Researchers are exploring nanoparticle-based delivery systems and peptide analogs to address these limitations, with CAS 17750-75-3 serving as a benchmark for structural modifications. Collaborative efforts between academic institutions and pharmaceutical companies are expected to accelerate the translation of these discoveries into clinical applications.

In conclusion, the latest research on b-Melanotropin (Macaca nemestrina)(9CI) and its associated chemical identifier, 17750-75-3, underscores its multifaceted potential in medicine. From dermatology to metabolic regulation, this peptide continues to reveal new therapeutic possibilities. However, ongoing studies must address challenges related to synthesis, delivery, and clinical efficacy to fully realize its benefits. This brief serves as a timely update for researchers and industry professionals invested in the future of peptide-based therapeutics.

17750-75-3 (b-Melanotropin (Macaca nemestrina)(9CI)) Related Products

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Amadis Chemical Company Limited
(CAS:17750-75-3)b-Melanotropin (Macaca nemestrina)(9CI)
A1139074
Purity:99%
Quantity:5mg
Price ($):492.0
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