Cas no 123168-37-6 ((2R)-2-ethyl-Pyrrolidine)

(2R)-2-ethyl-Pyrrolidine is a chiral pyrrolidine derivative characterized by its stereospecific (R)-configuration and an ethyl substituent at the 2-position. This compound serves as a valuable intermediate in asymmetric synthesis and pharmaceutical applications due to its rigid pyrrolidine scaffold, which enhances conformational control in chiral catalysts and ligands. Its ethyl group introduces steric and electronic modulation, making it useful for fine-tuning reactivity in organocatalysis and medicinal chemistry. The enantiomeric purity of (2R)-2-ethyl-Pyrrolidine ensures consistent performance in stereoselective transformations, while its stability under typical reaction conditions allows for broad utility. It is commonly employed in the synthesis of bioactive molecules and agrochemicals.
(2R)-2-ethyl-Pyrrolidine structure
(2R)-2-ethyl-Pyrrolidine structure
Product Name:(2R)-2-ethyl-Pyrrolidine
CAS No:123168-37-6
MF:C6H13N
MW:99.1741216182709
MDL:MFCD19217252
CID:1089745
PubChem ID:10931375
Update Time:2025-10-16

(2R)-2-ethyl-Pyrrolidine Chemical and Physical Properties

Names and Identifiers

    • (2R)-2-ethyl-Pyrrolidine
    • (2R)-2-ethylpyrrolidine
    • (R)-2-Ethylpyrrolidine
    • 2-Ethyl-pyrrolidine
    • (2R)-ethylpyrrolidine
    • QC-574
    • RB4030
    • (R)-2alpha-Ethylpyrrolidine
    • AKOS006348967
    • Pyrrolidine, 2-ethyl-, (R)-
    • DTXSID00448665
    • JFZLDRUSMYBXRI-ZCFIWIBFSA-N
    • MFCD19217252
    • 123168-37-6
    • 2-(R)-ethyl-pyrrolidine
    • DA-13978
    • MDL: MFCD19217252
    • Inchi: 1S/C6H13N/c1-2-6-4-3-5-7-6/h6-7H,2-5H2,1H3/t6-/m1/s1
    • InChI Key: JFZLDRUSMYBXRI-ZCFIWIBFSA-N
    • SMILES: N1CCC[C@H]1CC

Computed Properties

  • Exact Mass: 99.10480
  • Monoisotopic Mass: 99.104799419g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 1
  • Complexity: 52.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.2
  • Topological Polar Surface Area: 12?2

Experimental Properties

  • PSA: 12.03000
  • LogP: 1.47720

(2R)-2-ethyl-Pyrrolidine Pricemore >>

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(2R)-2-ethyl-Pyrrolidine Production Method

Additional information on (2R)-2-ethyl-Pyrrolidine

Recent Advances in the Study of (2R)-2-ethyl-Pyrrolidine and Its Derivative (CAS: 123168-37-6) in Chemical Biology and Pharmaceutical Research

The compound (2R)-2-ethyl-Pyrrolidine and its derivative with the CAS number 123168-37-6 have recently garnered significant attention in the field of chemical biology and pharmaceutical research. These molecules are pivotal in the development of novel therapeutic agents due to their unique structural properties and biological activities. Recent studies have focused on their synthesis, pharmacological evaluation, and potential applications in treating various diseases, including neurological disorders and cancer.

One of the key findings in recent research is the role of (2R)-2-ethyl-Pyrrolidine as a chiral building block in the synthesis of complex pharmaceutical compounds. Its enantiomeric purity and structural flexibility make it an ideal candidate for the development of stereospecific drugs. The derivative 123168-37-6, in particular, has shown promising results in preclinical studies as a potential inhibitor of specific enzymatic pathways involved in inflammatory responses.

Advanced spectroscopic techniques, such as NMR and mass spectrometry, have been employed to characterize the molecular structure and confirm the stereochemistry of these compounds. Computational modeling and molecular docking studies have further elucidated their binding mechanisms with target proteins, providing insights into their mode of action at the atomic level. These findings are crucial for optimizing their pharmacological profiles and minimizing off-target effects.

In addition to their therapeutic potential, recent studies have explored the scalability and cost-effectiveness of synthesizing (2R)-2-ethyl-Pyrrolidine and its derivatives. Green chemistry approaches, including catalytic asymmetric synthesis and solvent-free reactions, have been investigated to enhance the sustainability of their production. These advancements are expected to facilitate their transition from laboratory-scale research to industrial applications.

Despite the progress, challenges remain in the clinical translation of these compounds. Issues such as bioavailability, metabolic stability, and toxicity profiles need to be addressed through further research. Collaborative efforts between academia and industry are essential to overcome these hurdles and unlock the full potential of (2R)-2-ethyl-Pyrrolidine and 123168-37-6 in drug development.

In conclusion, the ongoing research on (2R)-2-ethyl-Pyrrolidine and its derivative 123168-37-6 highlights their significant promise in the pharmaceutical industry. Continued exploration of their biological activities and synthetic methodologies will undoubtedly contribute to the discovery of next-generation therapeutics.

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