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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Alpha-halocarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Alpha-halocarboxylic acids and derivatives Alpha-halocarboxylic acids

Comprehensive Introduction to 2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d (CAS No. 1215692-10-6)

2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d is a stable isotope-labeled derivative of bromoacetic acid, widely utilized in advanced research fields such as metabolomics, NMR spectroscopy, and tracer studies. With its unique isotopic enrichment (13C and deuterium), this compound serves as a critical tool for elucidating biochemical pathways and reaction mechanisms. Its CAS number, 1215692-10-6, ensures precise identification in scientific databases and regulatory documentation.

The growing demand for isotope-labeled compounds in pharmaceutical and environmental research has positioned 2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d as a sought-after reagent. Researchers leverage its high isotopic purity (≥98%) to minimize background noise in mass spectrometry and enhance signal resolution in quantitative analysis. Recent studies highlight its role in probing glycolytic pathways and protein interactions, aligning with the rising interest in precision medicine and biomarker discovery.

From a synthetic chemistry perspective, the compound’s bromoacetic acid backbone facilitates selective alkylation reactions, while its deuterium-labeled methylene group (-CD2) provides kinetic isotope effects (KIEs) for mechanistic investigations. This feature is particularly valuable in enzyme kinetics and drug metabolism studies, where understanding hydrogen/deuterium exchange is pivotal. The 13C-labeled carboxyl group further enables tracking of carbon flux in metabolic engineering applications.

In the context of sustainable chemistry, 2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d aligns with the push for green solvents and low-waste synthesis. Its use in catalysis research supports the development of eco-friendly industrial processes, a topic frequently searched in academic and industrial forums. Additionally, its stability under controlled conditions makes it suitable for long-term isotope dilution mass spectrometry (IDMS), a gold standard in analytical method validation.

Quality control of CAS No. 1215692-10-6 involves rigorous HPLC and GC-MS analyses to ensure compliance with ISO standards. Storage recommendations typically emphasize protection from light and moisture, with temperatures below –20°C to preserve isotopic integrity. These protocols cater to laboratories focusing on high-throughput screening and FDA-compliant assays, addressing common queries about reagent handling in peer-reviewed literature.

Emerging trends in personalized therapeutics and multi-omics integration further amplify the relevance of 2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d. For instance, its application in stable isotope-resolved metabolomics (SIRM) helps decode disease-specific metabolic reprogramming, a hotspot in cancer research and neurodegenerative disease studies. Such interdisciplinary connections enhance its visibility in search engines, where terms like "isotope-labeled probes for metabolism" and "13C tracer techniques" rank highly.

To summarize, 2-Bromoacetic-1,2-13C2-2,2-d2 Acid-d (CAS 1215692-10-6) bridges fundamental chemistry and cutting-edge life science applications. Its design caters to the increasing need for molecular precision in research, while its versatility addresses FAQs about isotopic labeling strategies and analytical reproducibility. As scientific inquiries grow more complex, this compound remains indispensable for innovators navigating the frontiers of chemical biology and diagnostic development.

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