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Comprehensive Overview of Methyl 2-Bromo-5-Chloropyridine-4-Carboxylate (CAS No. 1214336-33-0)

Methyl 2-bromo-5-chloropyridine-4-carboxylate (CAS No. 1214336-33-0) is a highly versatile heterocyclic compound widely utilized in pharmaceutical and agrochemical research. This pyridine derivative features a bromine and chlorine substitution pattern, along with a methyl ester functional group, making it a valuable intermediate in organic synthesis. Its molecular formula, C₇H₅BrClNO₂, highlights its potential for diverse chemical transformations, particularly in cross-coupling reactions and catalyzed processes.

In recent years, the demand for methyl 2-bromo-5-chloropyridine-4-carboxylate has surged due to its role in developing small-molecule inhibitors and biologically active compounds. Researchers frequently search for "synthesis of pyridine carboxylates" or "applications of halogenated pyridines," reflecting its relevance in drug discovery. The compound’s electron-withdrawing groups enhance its reactivity in nucleophilic aromatic substitution (S_NAr) reactions, a topic gaining traction in green chemistry discussions.

From an industrial perspective, CAS 1214336-33-0 is pivotal in optimizing process scalability and yield efficiency. Questions like "how to purify methyl 2-bromo-5-chloropyridine-4-carboxylate" or "stability under storage conditions" are common among chemists. The compound’s crystalline structure and solubility profiles are also critical for formulation studies, aligning with trends in high-throughput screening (HTS) methodologies.

Environmental and regulatory considerations further underscore the importance of methyl 2-bromo-5-chloropyridine-4-carboxylate. Searches for "eco-friendly synthesis routes" or "biodegradability of pyridine derivatives" highlight the shift toward sustainable practices. Innovations in catalytic reduction and solvent-free reactions are increasingly applied to minimize waste, resonating with the circular economy framework.

In summary, methyl 2-bromo-5-chloropyridine-4-carboxylate (CAS No. 1214336-33-0) bridges academic research and industrial applications, driven by its structural versatility and reactive sites. Its alignment with cutting-edge chemistry trends ensures continued relevance in scientific literature and patent filings.

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• 1256789-73-7(Methyl 6-bromo-4-chloronicotinate)
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• 211678-96-5(ethyl 3-chloropyridine-4-carboxylate)
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• 530156-90-2(2-bromo-5-chloropyridine-4-carboxylic acid)
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