Cas no 121123-17-9 (Cefprozil monohydrate)
Cefprozil monohydrate is a semi-synthetic cephalosporin antibiotic with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Its monohydrate form enhances stability and solubility, making it suitable for oral formulations. The compound exhibits efficacy against common pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus, making it valuable in treating respiratory, skin, and soft tissue infections. Its β-lactamase stability and favorable pharmacokinetic profile, including high oral bioavailability and prolonged half-life, contribute to its clinical utility. Cefprozil monohydrate is widely used in both pediatric and adult populations due to its reliable absorption and minimal side effects.
Cefprozil monohydrate structure
Product Name:Cefprozil monohydrate
CAS No:121123-17-9
MF:C18H21N3O6S
MW:407.440843343735
MDL:MFCD00911719
CID:63537
PubChem ID:6436628
Update Time:2025-11-01
Cefprozil monohydrate Chemical and Physical Properties
Names and Identifiers
-
- Cefprozil hydrate
- *>
- CEFZIL
- CEFPROZIL MONOHYDRATE
- (6r-(6alpha,7beta(r*)))-7-((amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- 8-[2-amino-2-(4-hydroxyphenyl)-acetyl]amino-7-oxo-4-prop-1-enyl-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid
- (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- ^]]-7-[[Amino(4-hydroxyphenyl)acetyl]amino]-8-ox-3-(1-propenyl)-5-thia-1-azabicyclo[4.2.0]oet-2-ene-2-carboxylic acid monohydrate
- CEFETAMET
- Cefprozil (monohydrate)
- Cefprozil hydrate (Cefzil)
- ceftibutin
- Unii-4W0459za4v
- Cefprozil (200 mg)
- BMY-28167：BBS-1067
- Cefprozil for Suspension
- DSSTox_CID_26085
- DSSTox_RID_81326
- DSSTox_GSID_46085
- Tox21_111731
- (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-prop-1-enyl-5-thia-1-azabicyclo[4.
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, monohydrate, (6R-(6alpha,7beta(R*)))-
- 5-Thia-1-azabicyclo(4.2.0)oct-2-oxo-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, monohydrate, (6R-(6alpha,7beta(R*))-)-
- AKOS015895264
- 92665-29-7
- CEFPROZIL, E-ISOMER
- MFCD00911719
- 3ADV90MJVU
- (E)-cefprozil hydrate
- 121123-17-9
- 4W0459ZA4V
- 1ST157166
- UNII-3ADV90MJVU
- Cefprozil (USP)
- NCGC00159513-02
- (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate
- s2544
- (6R,7R)-7-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-enyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- D00261
- DTXSID3046085
- Cefprozil (E)-Isomer (50 mg)
- 5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-((AMINO(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1-PROPENYL)-, MONOHYDRATE, (6R-(3(E),6.ALPHA.,7.BETA.(R*)))-
- CAS-121123-17-9
- SCHEMBL1230160
- C71745
- Q27256965
- Cefprozil, (E)-
- NSC 759099
- DTXCID1026085
- CEFPROZIL, (E)-ISOMER
- (6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-propenyl-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- 5-Thia-1-azabicyclo(4.2.0)oct-2-oxo-2-carboxylic acid, 7-(((2R)-amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-, monohydrate, (6R,7R)-
- KS-1039
- 5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYL)AMINO)-8-OXO-3-(1E)-1-PROPEN-1-YL-, HYDRATE (1:1), (6R,7R)-
- ALYUMNAHLSSTOU-CIRGZYLNSA-N
- Cefzil (TN)
- CFPZ
- SCHEMBL718721
- HY-B0458
- BMY-28100-03-800
- Cefprozil [USAN:USP:INN:BAN]
- AKOS040733092
- J-004449
- (6R,7R)-7-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate
- 111900-24-4
- Cefprozil for peak identification
- Cefprozil e-form
- CHEMBL5314373
- Cefprozil monohydrate
-
- MDL： MFCD00911719
- Inchi： 1S/C18H19N3O5S.H2O/c1-2-3-10-8-27-17-13(16(24)21(17)14(10)18(25)26)20-15(23)12(19)9-4-6-11(22)7-5-9;/h2-7,12-13,17,22H,8,19H2,1H3,(H,20,23)(H,25,26);1H2/b3-2+;/t12-,13-,17-;/m1./s1
- InChI Key： ALYUMNAHLSSTOU-CIRGZYLNSA-N
- SMILES： S1CC(/C=C/C)=C(C(=O)O)N2C([C@H]([C@@H]12)NC([C@@H](C1C=CC(=CC=1)O)N)=O)=O.O
Computed Properties
- Exact Mass: 407.11510657g/mol
- Monoisotopic Mass: 407.11510657g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 5
- Hydrogen Bond Acceptor Count: 8
- Heavy Atom Count: 28
- Rotatable Bond Count: 5
- Complexity: 699
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 3
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 1
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 159
Experimental Properties
- Boiling Point: 803.077°C at 760 mmHg
Cefprozil monohydrate Security Information
- Signal Word：Warning
- Hazard Statement： H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Hazard Category Code： R36/37/38: irritating to eyes, respiratory tract and skin. R42/43: inhalation and skin contact can cause allergy.
- Safety Instruction： S22: do not breathe dust. S26: in case of contact with eyes, immediately flush with plenty of water and send to a doctor for treatment. S36/37/39: wear appropriate protective clothing, gloves and protective glasses or face shield.
-
Hazardous Material Identification：
- Risk Phrases：R36/37/38
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Cefprozil monohydrate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C302631-200mg |
Cefprozil monohydrate |
121123-17-9 | ≥90% (on dry basis) | 200mg |
￥119.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | C302631-1g |
Cefprozil monohydrate |
121123-17-9 | ≥90% (on dry basis) | 1g |
￥393.90 | 2023-09-03 | |
| S e l l e c k ZHONG GUO | S2544-5mg |
Cefprozil hydrate |
121123-17-9 | 5mg |
￥1415.15 | 2023-09-16 | ||
| Chemenu | CM248204-50mg |
Cefprozil monohydrate |
121123-17-9 | 98% | 50mg |
$117 | 2021-06-09 | |
| ChemScence | CS-2569-10mg |
Cefprozil (monohydrate) |
121123-17-9 | 99.91% | 10mg |
$78.0 | 2022-04-28 | |
| ChemScence | CS-2569-50mg |
Cefprozil (monohydrate) |
121123-17-9 | 99.91% | 50mg |
$144.0 | 2022-04-28 | |
| TRC | C243933-50mg |
Cefprozil Monohydrate (E/Z Mixture) |
121123-17-9 | 50mg |
$ 51.00 | 2023-04-18 | ||
| TRC | C243933-500mg |
Cefprozil Monohydrate (E/Z Mixture) |
121123-17-9 | 500mg |
$ 80.00 | 2023-09-08 | ||
| TRC | C243933-1g |
Cefprozil Monohydrate (E/Z Mixture) |
121123-17-9 | 1g |
$ 114.00 | 2023-09-08 | ||
| TRC | C243933-2.5g |
Cefprozil Monohydrate (E/Z Mixture) |
121123-17-9 | 2.5g |
$ 215.00 | 2023-04-18 |
Cefprozil monohydrate Related Literature
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Yun-He Hong,Xiu-Li Xu,Wei-Qing Li,Bo-Zhou Xu,Han-Qiu Wu,Yan Cheng,Hong Chen,Bao-Shan Zhang,Feng Zhang Anal. Methods 2017 9 6534
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Gangarajula Sudhakar,Karla Janardhan Reddy,Jagadesh Babu Nanubolu Org. Biomol. Chem. 2015 13 8875
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Gholam Hossein Hakimelahi,Pai-Chi Li,Ali A. Moosavi-Movahedi,Jamshid Chamani,Ghadam Ali Khodarahmi,Tai Wei Ly,Famil Valiyev,Max K. Leong,Shahram Hakimelahi,Kak-Shan Shia,Ito Chao Org. Biomol. Chem. 2003 1 2461
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Kassidy O'Malley,Walter McDonald,Patrick McNamara Environ. Sci.: Water Res. Technol. 2023 9 2188
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Min Wang,Yadong Xue,Jian-Hong Zhu,Ai-Jun Wang,Li-Ping Mei,Pei Song New J. Chem. 2021 45 22833
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