Cas no 120-97-8 (Dichlorphenamide)

Dichlorphenamide is a sulfonamide-derived carbonic anhydrase inhibitor primarily used in the management of glaucoma and certain metabolic alkalosis conditions. Its mechanism of action involves reducing intraocular pressure by inhibiting carbonic anhydrase in the ciliary processes, thereby decreasing aqueous humor production. Additionally, it promotes renal bicarbonate excretion, making it effective in correcting metabolic imbalances. Key advantages include its dual therapeutic applications, predictable pharmacokinetics, and well-documented efficacy in clinical settings. The compound exhibits high specificity for carbonic anhydrase isoforms, minimizing off-target effects. Its stability and solubility profile facilitate formulation flexibility. Dichlorphenamide is recognized for its established safety profile when administered under appropriate medical supervision.

Dichlorphenamide structure

Product Name:Dichlorphenamide

CAS No:120-97-8

MF:C₆H₆Cl₂N₂O₄S₂

MW:305.158836841583

MDL:MFCD00148948

CID:35977

PubChem ID:329749374

Update Time:2025-06-06

Dichlorphenamide Chemical and Physical Properties

Names and Identifiers

- dichlorphenamide
- 4,5-dichlorobenzene-1,3-disulphonamide
- Dichlorophenamide
- Diclofenamide
- 4,5-Dichlorobenzene-1,3-disulfonamide
- Dichlorphenamide(Diclofenamide)
- 4,5-Dichloro-1,3-benzenedisulfonamide
- cb8000
- glaucol
- Oratrol
- Glaucor
- Oralcon
- daramide
- Daranide
- Dasanide
- Dalanide
- CB 8000
- Dichlofenamide
- Antidrasi
- Dichlorphenamid
- Glauconide
- Diclofenamidum
- Diclofenamida
- Diclofenamid
- Barastonin
- 1,3-Benzenedisulfonamide, 4,5-dichloro-
- Glaumid
- Glafco
- Glajust
- 4,5-Dichloro-m-benzenedisulfonamide
- Diclofenamidum [INN-Latin]
- 4,5-Dichloro-1,3-disulfamoylbenzene
- 1,3-Disulfamoyl-4,5-dichlorobenzene
- Diclofenamida [INN-Spanish]
- 1,3-Disulfamyl-4,5-dichlorobenzene
- Keveyis
- Dasan
- Tox21_110401
- NCGC00016371-04
- DTXSID1022922
- 4,5-Dichloro-benzene-1,3-disulfonic acid diamide
- HMS1570B19
- CHEBI:101085
- Q3706987
- DICHLORPHENAMIDE (USP-RS)
- CAS-120-97-8
- AKOS015899860
- DICHLORPHENAMIDE [MI]
- SPBio_002598
- s2177
- MLS002154010
- Diclofenamide (JAN/INN)
- Dichlorphenamide (USP)
- CCG-220809
- HMS2097B19
- 2pou
- BRD-K71499074-001-03-8
- Prestwick0_000809
- I7A
- Dichlorphenamide [USP]
- HSDB 3267
- DICHLORPHENAMIDE (USP IMPURITY)
- EN300-761460
- NCGC00016371-05
- 3,4-Dichloro-5-sulfamylbenzenesulfonamide
- FT-0648264
- Prestwick2_000809
- DICLOFENAMIDE [WHO-DD]
- W-108466
- HMS2236I07
- NCGC00016371-08
- 4,5-Dichloro-1,3-benzenedisulfonamide #
- NCGC00016371-06
- BRN 2703329
- Prestwick1_000809
- HMS3655H06
- Diclofenamide [INN]
- AMY7513
- DICLOFENAMIDE [JAN]
- NCGC00016371-01
- DICHLORPHENAMIDE [USP IMPURITY]
- 4,5-Dichloro-m-benzendisulfonamide
- DICHLOFENAMID
- DICHLORPHENAMIDE [USP MONOGRAPH]
- Diclofenamida (INN-Spanish)
- C07459
- EX-A1311
- AS-63955
- Diclofenamide; Dichlofenamide; Daranide; 4,5-dichlorobenzene-1,3-disulfonamide
- HMS3714B19
- 4,5-Dicholorobenzene-1,3-disulfonamide
- CHEMBL17
- 4,5-dichlorobenzene1,3-disulfonamide
- D00518
- GTPL6807
- DICHLORPHENAMIDE (USP MONOGRAPH)
- DICHLORPHENAMIDE [HSDB]
- UNII-VVJ6673MHY
- F90397
- Dichlorphenamide (Diclofenamide)
- A21072
- Prestwick_1071
- DICHLORPHENAMIDE [USP-RS]
- EINECS 204-440-6
- NS00004452
- Diclorfenamida
- Dichlorophenamide (DCP)
- Daranide (TN)
- SW197138-3
- Prestwick3_000809
- SMR001233338
- sulfonamide 4
- Diclorfenammide
- Keveyis (TN)
- DTXCID402922
- AC-25007
- NCGC00016371-02
- BCP22591
- DICHLORPHENAMIDE [ORANGE BOOK]
- HMS3745K19
- Z2037279821
- m-Benzenedisulfonamide, 4,5-dichloro-
- DICLOFENAMIDE (MART.)
- SR-01000841825
- MFCD00148948
- HY-B0397
- 120-97-8
- DB01144
- SCHEMBL112376
- SR-01000841825-2
- S01EC02
- BSPBio_000677
- HMS3373G04
- VVJ6673MHY
- DICLOFENAMIDE [MART.]
- BDBM10883
- DICHLORPHENAMIDE, SECONDARY STANDARD
- Dichlorophenamide, DCP
- Dichlorphenamide, United States Pharmacopeia (USP) Reference Standard
- BPBio1_000745
- Diclofenamidum (INN-Latin)
- GLXC-02996
- Dichlorphenamide (Diclofenamide)?
- BRD-K71499074-001-12-9
- 204-440-6
- HY-B0397R
- Dichlorphenamide (Standard)
- RFC05476
- Dichlorphenamide
- MDL： MFCD00148948
- Inchi： 1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)
- InChI Key： GJQPMPFPNINLKP-UHFFFAOYSA-N
- SMILES： ClC1=C(C=C(C=C1S(N)(=O)=O)S(N)(=O)=O)Cl

Computed Properties

Exact Mass: 303.91500
Monoisotopic Mass: 303.915
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 6
Heavy Atom Count: 16
Rotatable Bond Count: 2
Complexity: 452
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 0.3
Topological Polar Surface Area: 137

Experimental Properties

Color/Form: White or nearly white crystalline powder
Density: 1.7263 (rough estimate)
Melting Point: 239-241° (patent, mp 228.5-229°)
Boiling Point: 590.5 °C at 760 mmHg
Flash Point: 310.9 °C
Refractive Index: 1.6000 (estimate)
PSA: 137.08000
LogP: 3.85040

Dichlorphenamide Security Information

Hazardous Material transportation number：NONH for all modes of transport
Hazard Category Code： 63
Safety Instruction： S36
RTECS：CZ9200000
Hazardous Material Identification：
Safety Term：S36
Risk Phrases：R63
Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month

Dichlorphenamide Customs Data

HS CODE：2935009090
Customs Data：

China Customs Code:
2935009090

Overview:

2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

Declaration elements:

Product Name, component content, use to

Summary:

2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Dichlorphenamide Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YA200-10mg	Dichlorphenamide	120-97-8	98+%	10mg	1079CNY	2021-05-07
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-YA200-50mg	Dichlorphenamide	120-97-8	98+%	50mg	2341CNY	2021-05-07
MedChemExpress	HY-B0397-10mM*1mLinDMSO	Dichlorphenamide	120-97-8	98.39%	10mM*1mLinDMSO	￥935	2022-05-18
MedChemExpress	HY-B0397-10mg	Dichlorphenamide	120-97-8	98.90%	10mg	￥400	2024-04-20
MedChemExpress	HY-B0397-50mg	Dichlorphenamide	120-97-8	98.90%	50mg	￥1200	2024-04-20
MedChemExpress	HY-B0397-100mg	Dichlorphenamide	120-97-8	98.90%	100mg	￥2800	2023-08-31
S e l l e c k ZHONG GUO	S2177-10mg	Dichlorphenamide	120-97-8	99.21%	10mg	￥2601.58	2023-09-16
ChemScence	CS-2491-10mg	Dichlorphenamide	120-97-8	98.39%	10mg	$92.0	2022-04-28
ChemScence	CS-2491-50mg	Dichlorphenamide	120-97-8	98.39%	50mg	$158.0	2022-04-28
ChemScence	CS-2491-100mg	Dichlorphenamide	120-97-8	98.39%	100mg	$275.0	2022-04-28

Dichlorphenamide Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:120-97-8)Dichlorphenamide

Order Number:A21072

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 04:11

Price ($):288.0

Email:[email protected]

Product Official Link

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