Cas no 119967-49-6 (2-(pyridin-3-yloxy)ethan-1-ol)

2-(Pyridin-3-yloxy)ethan-1-ol is a versatile heterocyclic compound featuring a pyridine ring linked to an ethanol moiety via an ether bond. This structure imparts unique reactivity, making it valuable as an intermediate in pharmaceutical and agrochemical synthesis. Its polar functional groups enhance solubility in both aqueous and organic solvents, facilitating diverse chemical modifications. The pyridine ring offers coordination sites for metal complexes, while the hydroxyl group enables further derivatization, such as esterification or etherification. The compound’s stability under mild conditions and compatibility with common reagents make it suitable for scalable applications. Its balanced hydrophilicity and lipophilicity also contribute to its utility in drug design and material science.
2-(pyridin-3-yloxy)ethan-1-ol structure
2-(pyridin-3-yloxy)ethan-1-ol structure
Product Name:2-(pyridin-3-yloxy)ethan-1-ol
CAS No:119967-49-6
MF:C7H9NO2
MW:139.151861906052
MDL:MFCD13248572
CID:132342
PubChem ID:21908997
Update Time:2025-05-20

2-(pyridin-3-yloxy)ethan-1-ol Chemical and Physical Properties

Names and Identifiers

    • 2-(3-pyridinyloxy)-Ethanol
    • 2-pyridin-3-yloxyethanol
    • Ethanol, 2-(3-pyridinyloxy)-
    • 2-(pyridin-3-yloxy)ethanol
    • 2-(3-Pyridyloxy)ethanol
    • 2-(Pyridyl-3-yloxy)ethanol
    • 2-(3-Pyridinyloxy)ethanol
    • 3-(2-hydroxyethoxy)pyridine
    • Ethanol, 2-(3-pyridinyloxy)- (9CI)
    • 2-(pyridin-3-yloxy)ethan-1-ol
    • MFCD13248572
    • CS-0195537
    • DTXSID00619919
    • F8881-3377
    • SCHEMBL238711
    • SB54083
    • 2-[(Pyridin-3-yl)oxy]ethan-1-ol
    • Ethanol,2-(3-pyridinyloxy)-
    • Z1180078238
    • 2(3-pyridinyloxy)ethanol
    • EN300-77271
    • 2-[(3-pyridinyl)oxy]ethanol
    • 2-(pyridin-3-yloxy)-ethanol
    • D86242
    • IFBXNOIFACMNNE-UHFFFAOYSA-N
    • AS-59494
    • A21122
    • FT-0718272
    • 119967-49-6
    • AKOS013258563
    • DB-013939
    • MDL: MFCD13248572
    • Inchi: 1S/C7H9NO2/c9-4-5-10-7-2-1-3-8-6-7/h1-3,6,9H,4-5H2
    • InChI Key: IFBXNOIFACMNNE-UHFFFAOYSA-N
    • SMILES: O(C1C=NC=CC=1)CCO

Computed Properties

  • Exact Mass: 139.06337
  • Monoisotopic Mass: 139.063328530g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 3
  • Complexity: 87.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.4
  • Topological Polar Surface Area: 42.4?2

Experimental Properties

  • Density: 1.153
  • Melting Point: 98-99 oC
  • Boiling Point: 272 oC
  • Flash Point: 119 oC
  • Refractive Index: 1.528
  • PSA: 42.35
  • LogP: 0.45270

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Additional information on 2-(pyridin-3-yloxy)ethan-1-ol

2-(Pyridin-3-yloxy)ethan-1-ol: A Comprehensive Overview

2-(Pyridin-3-yloxy)ethan-1-ol, also known by its CAS registry number 119967-49-6, is a versatile organic compound with significant applications in various fields of chemistry and materials science. This compound, characterized by its unique structure featuring a pyridine ring and a hydroxyl group, has garnered attention due to its potential in drug design, catalysis, and advanced materials development. Recent studies have further elucidated its properties, making it a subject of interest for both academic and industrial research.

The molecular structure of 2-(pyridin-3-yloxy)ethan-1-ol is defined by the presence of a pyridine ring substituted with an ether group (-O-) connected to an ethanol moiety. This arrangement imparts the compound with unique electronic and steric properties, which are crucial for its reactivity and functionality. The pyridine ring, being aromatic and electron-deficient, facilitates various chemical transformations, while the hydroxyl group introduces hydrogen bonding capabilities, enhancing solubility and interaction with polar environments.

Recent advancements in synthetic methodologies have enabled the efficient preparation of 2-(pyridin-3-yloxy)ethan-1-ol through diverse routes, including nucleophilic substitution and coupling reactions. These methods not only improve yield but also allow for precise control over the compound's purity and stereochemistry. The ability to synthesize this compound in large quantities has further expanded its applicability in industrial settings.

One of the most promising applications of 2-(pyridin-3-yloxy)ethan-1-ol lies in its role as a precursor for advanced materials. Researchers have explored its use in the synthesis of metal complexes, which exhibit exceptional catalytic activity in organic transformations. For instance, studies have demonstrated that transition metal complexes derived from this compound can effectively catalyze cross-coupling reactions, offering a sustainable alternative to traditional catalysts.

In the pharmaceutical industry, 2-(pyridin-3-yloxy)ethan-1-ol has shown potential as an intermediate in drug design. Its ability to act as a chelating agent makes it valuable in the development of metal-based drugs targeting diseases such as cancer and neurodegenerative disorders. Recent research highlights its role in stabilizing metal ions within drug molecules, enhancing their bioavailability and efficacy.

The environmental impact of 2-(pyridin-3-yloxy)ethan-1-ol has also been a focal point of recent investigations. Studies indicate that this compound exhibits biodegradability under specific conditions, reducing its ecological footprint. Additionally, its use in green chemistry applications has been explored, emphasizing its role in sustainable chemical processes.

In conclusion, 2-(pyridin-3-yloxy)ethan-1-ol (CAS No. 119967496) stands out as a multifaceted compound with immense potential across various domains. Its unique chemical properties, coupled with recent advancements in synthesis and application techniques, position it as a key player in modern chemical research. As ongoing studies continue to uncover new facets of this compound's utility, its significance in both academic and industrial settings is expected to grow further.

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