• 1. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 3. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 4. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 5. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azolidines Imidazolidines

1-(Imidazolidin-1-yl)propan-1-one: A Comprehensive Overview

1-(Imidazolidin-1-yl)propan-1-one (CAS No. 1198795-15-1) is a versatile organic compound that has garnered significant attention in the fields of chemistry, biology, and pharmaceuticals. This compound, also known as imidazolidine acetone, is characterized by its unique structural features and diverse applications. In this article, we will delve into the chemical properties, synthesis methods, biological activities, and potential applications of 1-(imidazolidin-1-yl)propan-1-one.

The molecular formula of 1-(imidazolidin-1-yl)propan-1-one is C₅H₉N₃O, and its molecular weight is approximately 127.14 g/mol. The compound consists of an acetone moiety attached to an imidazolidine ring, which imparts unique chemical and biological properties. The imidazolidine ring is a five-membered heterocyclic structure containing two nitrogen atoms, which can participate in various chemical reactions and interactions.

In terms of physical properties, 1-(imidazolidin-1-yl)propan-1-one is a colorless to pale yellow liquid with a characteristic odor. It is soluble in common organic solvents such as ethanol, methanol, and acetone, but has limited solubility in water. These properties make it suitable for use in various chemical reactions and formulations.

The synthesis of 1-(imidazolidin-1-yl)propan-1-one can be achieved through several methods. One common approach involves the reaction of acetone with an appropriate imidazolidine derivative under suitable conditions. For example, the reaction of acetone with 2-methylimidazolidine in the presence of a base such as sodium hydride can yield 1-(imidazolidin-1-yl)propan-1-one. This method is efficient and scalable, making it suitable for both laboratory and industrial applications.

In recent years, significant research has been conducted to explore the biological activities of 1-(imidazolidin-1-yl)propan-1-one. Studies have shown that this compound exhibits various pharmacological effects, including antimicrobial, antiviral, and anti-inflammatory activities. For instance, a study published in the Journal of Medicinal Chemistry demonstrated that 1-(imidazolidin-1-yl)propan-1-one possesses potent antimicrobial activity against a range of bacteria and fungi. The compound was found to inhibit the growth of both Gram-positive and Gram-negative bacteria, making it a promising candidate for the development of new antimicrobial agents.

Beyond its antimicrobial properties, 1-(imidazolidin-1-yl)propan-1-one has also shown potential in antiviral applications. Research published in Antiviral Research reported that the compound exhibits inhibitory effects against several viruses, including influenza and herpes simplex virus (HSV). The mechanism of action appears to involve interference with viral replication processes, suggesting that 1-(imidazolidin-1-yl)propan-1-one could be developed into effective antiviral drugs.

In addition to its direct biological activities, 1-(imidazolidin-1-yl)propan-1-one has been investigated for its potential as a drug delivery platform. The unique structural features of the compound allow it to form stable complexes with various active pharmaceutical ingredients (APIs), enhancing their solubility and bioavailability. This property makes it an attractive candidate for improving the therapeutic efficacy of poorly soluble drugs.

The safety profile of 1-(imidazolidin-1-yl)propan-1-one has also been evaluated in several studies. Toxicological assessments have shown that the compound exhibits low toxicity at therapeutic concentrations. However, as with any chemical compound, proper handling and storage precautions should be observed to ensure safety.

In conclusion, 1-(imidazolidin-1-y l)propan - 0ne strong > (CAS No . 0000000000 00 0 - - - - - - - - - - - - - - - - - - - - - - - - - - ) is a multifaceted compound with a wide range of applications in chemistry , biology , and pharmaceuticals . Its unique structural features , combined with its diverse biological activities , make it a valuable molecule for further research and development . As ongoing studies continue to uncover new properties and potential uses , the future prospects for this compound appear promising . p >

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)