• 1. An investigation of surface properties, local elastic modulus and interaction with simulated pulmonary surfactant of surface modified inhalable voriconazole dry powders using atomic force microscopy
  Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
• 2. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
• 3. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
• 4. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 5. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Thiophenes Thiophene carboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Thiophenes Thiophene carboxylic acids and derivatives Thiophene carboxylic acids

Exploring the Potential of 5-(Pyridin-2-yl)thiophene-2-carboxylic Acid: A Comprehensive Overview

5-(Pyridin-2-yl)thiophene-2-carboxylic acid, also known by its CAS number CAS No. 119082-97-2, is a fascinating compound that has garnered significant attention in the fields of organic chemistry and materials science. This compound, characterized by its unique structure featuring a pyridine ring fused with a thiophene moiety and a carboxylic acid group, exhibits intriguing properties that make it a subject of extensive research.

The synthesis of 5-(Pyridin-2-yl)thiophene-2-carboxylic acid involves a series of well-defined organic reactions, including coupling reactions and oxidation processes. Recent advancements in synthetic methodologies have enabled chemists to achieve higher yields and better purity levels, making this compound more accessible for further studies. The structural integrity of this molecule is crucial for its applications, as minor structural variations can significantly alter its chemical reactivity and physical properties.

One of the most notable aspects of CAS No. 119082-97-2 is its electronic properties. The thiophene ring, known for its aromaticity and conjugation capabilities, plays a pivotal role in determining the compound's electronic behavior. Recent studies have demonstrated that this compound can act as an efficient electron acceptor in organic photovoltaic (OPV) devices, making it a promising candidate for next-generation solar cells. The integration of the pyridine group further enhances its electron-withdrawing capabilities, which is advantageous for charge transport in these devices.

In addition to its electronic properties, 5-(Pyridin-2-yl)thiophene-2-carboxylic acid has shown potential in the field of drug discovery. Its ability to form hydrogen bonds due to the carboxylic acid group makes it an attractive ligand for metalloenzyme inhibition studies. Recent research has highlighted its potential as a lead compound for developing inhibitors against certain proteases, which are implicated in various pathological conditions such as cancer and neurodegenerative diseases.

The thermal stability and solubility characteristics of this compound are also worth mentioning. Studies have shown that CAS No. 119082-97-2 exhibits good thermal stability up to moderate temperatures, making it suitable for various high-throughput screening processes. Its solubility in common organic solvents further facilitates its use in laboratory settings and industrial applications.

From an environmental standpoint, the biodegradability and eco-friendliness of 5-(Pyridin-2-yI)thiophene-2-carboxylic acid have been under scrutiny. Recent eco-toxicological studies suggest that this compound has low toxicity towards aquatic organisms, which is a positive indicator for its potential use in environmentally benign chemical processes.

In conclusion, CAS No. 119082 - 97 - 2, or 5-(Pyridin - 2 - yl) thiophene - 2 - carboxylic acid, stands out as a versatile compound with diverse applications across multiple disciplines. Its unique structure, coupled with favorable electronic and physical properties, positions it as a key player in advancing modern materials science and therapeutic development.

• 656226-31-2(2-Thiophenecarboxylic acid, 5-[6-[(phenylmethoxy)methyl]-2-pyridinyl]-,methyl ester)
• 656227-41-7(5-(6-formylpyridin-2-yl)thiophene-2-carboxylic acid)
• 132706-12-8(5-(Pyridin-2-yl)thiophene-2-carbaldehyde)
• 197899-76-6(2-(Hydroxymethyl)-5-(pyridin-2-yl)thiophene)
• 656227-35-9(2-Thiophenecarboxylic acid, 5-(6-amino-2-pyridinyl)-)
• 656226-84-5(2-Thiophenecarboxylic acid,5-[6-[[(3-pyridinylmethyl)amino]methyl]-2-pyridinyl]-)
• 500997-73-9(2-Thiophenecarboxylic acid, 5-(pyridinyl)-)
• 887981-86-4(6-(thiophen-2-yl)picolinic acid)
• 179408-54-9(6-(2-Thienyl)nicotinic Acid)
• 893723-57-4(2-(thiophen-2-yl)isonicotinic acid)