Cas no 1190312-91-4 (3-Bromo-5-cyano-4-methyl-7-azaindole)

3-Bromo-5-cyano-4-methyl-7-azaindole is a heterocyclic compound featuring a fused pyridine-pyrrole (7-azaindole) core with bromo, cyano, and methyl substituents. This structure enhances its utility as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. The bromo group offers reactivity for cross-coupling reactions, while the cyano functionality provides a handle for further derivatization. The methyl group contributes to steric and electronic modulation, influencing binding affinity in target applications. Its well-defined reactivity profile and stability under standard conditions make it a valuable building block for medicinal chemistry and materials science research.
3-Bromo-5-cyano-4-methyl-7-azaindole structure
1190312-91-4 structure
Product Name:3-Bromo-5-cyano-4-methyl-7-azaindole
CAS No:1190312-91-4
MF:C9H6BrN3
MW:236.068040370941
CID:2169187
Update Time:2025-05-21

3-Bromo-5-cyano-4-methyl-7-azaindole Chemical and Physical Properties

Names and Identifiers

    • 3-Bromo-5-cyano-4-methyl-7-azaindole
    • 3-bromo-4-methyl-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile
    • FCH1378741
    • AK316628
    • Inchi: 1S/C9H6BrN3/c1-5-6(2-11)3-12-9-8(5)7(10)4-13-9/h3-4H,1H3,(H,12,13)
    • InChI Key: TVRMCXFWGLWFBP-UHFFFAOYSA-N
    • SMILES: BrC1=CNC2C1=C(C)C(C#N)=CN=2

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 0
  • Complexity: 247
  • Topological Polar Surface Area: 52.5

3-Bromo-5-cyano-4-methyl-7-azaindole Pricemore >>

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Additional information on 3-Bromo-5-cyano-4-methyl-7-azaindole

Comprehensive Overview of 3-Bromo-5-cyano-4-methyl-7-azaindole (CAS No. 1190312-91-4)

3-Bromo-5-cyano-4-methyl-7-azaindole (CAS No. 1190312-91-4) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research. This 7-azaindole derivative is characterized by its unique molecular structure, featuring a bromo substituent at the 3-position, a cyano group at the 5-position, and a methyl group at the 4-position. Such structural attributes make it a valuable intermediate in the synthesis of bioactive molecules, particularly in the development of kinase inhibitors and other therapeutic agents.

The growing interest in 3-Bromo-5-cyano-4-methyl-7-azaindole is driven by its potential applications in drug discovery. Researchers are increasingly exploring its utility in targeting protein kinases, which play a critical role in cell signaling pathways. Kinase dysregulation is associated with various diseases, including cancer, inflammation, and neurodegenerative disorders. As a result, compounds like 3-Bromo-5-cyano-4-methyl-7-azaindole are being investigated for their ability to modulate these pathways, offering promising avenues for novel therapeutics.

In addition to its pharmaceutical relevance, 3-Bromo-5-cyano-4-methyl-7-azaindole is also studied for its agrochemical potential. The 7-azaindole scaffold is known for its herbicidal and pesticidal properties, making it a candidate for developing next-generation crop protection agents. With the global push toward sustainable agriculture, the demand for innovative and environmentally friendly agrochemicals is rising, further highlighting the importance of this compound.

From a synthetic chemistry perspective, 3-Bromo-5-cyano-4-methyl-7-azaindole serves as a versatile building block. Its reactive sites, including the bromo and cyano groups, allow for further functionalization through cross-coupling reactions, nucleophilic substitutions, and other transformations. This flexibility enables chemists to tailor the compound for specific applications, enhancing its utility in diverse research fields.

The compound's stability and solubility properties are also noteworthy. 3-Bromo-5-cyano-4-methyl-7-azaindole exhibits moderate solubility in common organic solvents, facilitating its use in laboratory settings. Its stability under standard conditions ensures reliable performance in synthetic workflows, making it a preferred choice for researchers.

As the scientific community continues to explore the potential of 7-azaindole derivatives, 3-Bromo-5-cyano-4-methyl-7-azaindole stands out as a compound with broad applicability. Its role in advancing drug discovery and agrochemical innovation underscores its significance in modern research. For those seeking high-quality intermediates with proven efficacy, this compound represents a compelling option.

In summary, 3-Bromo-5-cyano-4-methyl-7-azaindole (CAS No. 1190312-91-4) is a multifaceted compound with immense potential in both pharmaceutical and agrochemical industries. Its unique structural features, combined with its reactivity and stability, make it a valuable asset for researchers aiming to develop next-generation solutions for global challenges in health and agriculture.

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