Cas no 1187928-19-3 (Methyl-thiazol-2-ylmethyl-amine hydrochloride)

Methyl-thiazol-2-ylmethyl-amine hydrochloride is a hydrochloride salt derivative of a thiazole-containing amine, commonly utilized as a versatile intermediate in organic synthesis and pharmaceutical research. Its thiazole moiety imparts structural diversity, making it valuable for the development of biologically active compounds, particularly in medicinal chemistry. The hydrochloride form enhances solubility and stability, facilitating handling and storage. This compound is often employed in the synthesis of heterocyclic frameworks, ligands, and small-molecule inhibitors. Its well-defined chemical properties and reactivity profile make it a reliable building block for targeted molecular design. Suitable for controlled environments, it requires standard precautions for amine and salt handling.
Methyl-thiazol-2-ylmethyl-amine hydrochloride structure
1187928-19-3 structure
Product Name:Methyl-thiazol-2-ylmethyl-amine hydrochloride
CAS No:1187928-19-3
MF:C5H9ClN2S
MW:164.656358480453
MDL:MFCD09878928
CID:2604052
Update Time:2025-10-23

Methyl-thiazol-2-ylmethyl-amine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • Methyl-thiazol-2-ylMethylaMine hydrochloride
    • METHYL-THIAZOL-2-YLMETHYL-AMINE HYDROCHLORIDE
    • methyl[(1,3-thiazol-2-yl)methyl]amine hydrochloride
    • Methyl-thiazol-2-ylmethyl-amine hydrochloride
    • MDL: MFCD09878928
    • Inchi: 1S/C5H8N2S.ClH/c1-6-4-5-7-2-3-8-5;/h2-3,6H,4H2,1H3;1H
    • InChI Key: DWGDRTVCTNLRKZ-UHFFFAOYSA-N
    • SMILES: Cl.S1C=CN=C1CNC

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 2
  • Complexity: 67.4
  • Topological Polar Surface Area: 53.2

Methyl-thiazol-2-ylmethyl-amine hydrochloride Security Information

Methyl-thiazol-2-ylmethyl-amine hydrochloride Pricemore >>

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Additional information on Methyl-thiazol-2-ylmethyl-amine hydrochloride

Recent Advances in the Study of Methyl-thiazol-2-ylmethyl-amine hydrochloride (CAS: 1187928-19-3)

Methyl-thiazol-2-ylmethyl-amine hydrochloride (CAS: 1187928-19-3) is a chemical compound that has garnered significant attention in the field of chemical biology and pharmaceutical research. This compound, characterized by its thiazole moiety and amine hydrochloride functionality, has been investigated for its potential applications in drug discovery and development. Recent studies have explored its role as a building block in the synthesis of novel bioactive molecules, particularly in the context of kinase inhibitors and antimicrobial agents.

One of the key areas of interest is the compound's utility in the design of kinase inhibitors. Kinases are critical targets in the treatment of various diseases, including cancer and inflammatory disorders. Researchers have utilized Methyl-thiazol-2-ylmethyl-amine hydrochloride as a precursor in the synthesis of small-molecule inhibitors that selectively target specific kinase pathways. Recent findings suggest that derivatives of this compound exhibit promising inhibitory activity against certain kinases, with potential implications for the development of next-generation therapeutics.

In addition to its role in kinase inhibition, Methyl-thiazol-2-ylmethyl-amine hydrochloride has also been studied for its antimicrobial properties. Preliminary studies indicate that this compound and its derivatives possess activity against a range of bacterial and fungal pathogens. This has led to further investigations into its mechanism of action, with a focus on identifying structural modifications that could enhance its efficacy and reduce potential toxicity. The compound's versatility as a scaffold for antimicrobial drug design underscores its importance in addressing the growing challenge of antibiotic resistance.

The synthesis and characterization of Methyl-thiazol-2-ylmethyl-amine hydrochloride have been refined in recent years, with advancements in both chemical and enzymatic methodologies. These improvements have enabled more efficient production of the compound and its derivatives, facilitating broader exploration of its pharmacological potential. Furthermore, computational modeling and structure-activity relationship (SAR) studies have provided valuable insights into the compound's binding interactions with biological targets, guiding the rational design of optimized derivatives.

Despite these promising developments, challenges remain in the clinical translation of Methyl-thiazol-2-ylmethyl-amine hydrochloride-based therapeutics. Issues such as bioavailability, metabolic stability, and off-target effects need to be addressed through further preclinical and clinical studies. However, the compound's unique chemical properties and demonstrated bioactivity make it a compelling candidate for continued investigation.

In conclusion, Methyl-thiazol-2-ylmethyl-amine hydrochloride (CAS: 1187928-19-3) represents a valuable tool in the arsenal of chemical biology and pharmaceutical research. Its applications in kinase inhibition and antimicrobial therapy highlight its potential to contribute to the development of novel therapeutic agents. Ongoing research efforts are expected to further elucidate its mechanisms of action and optimize its pharmacological profile, paving the way for future clinical applications.

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