• 1. Evidence of field induced slow magnetic relaxation in cis-[Co(hfac)2(H2O)2] exhibiting tri-axial anisotropy with a negative axial component?
  Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
• 2. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 3. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 4. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 5. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid amides

Comprehensive Overview of 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS No. 1183184-66-8)

2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS No. 1183184-66-8) is a specialized organic compound that has garnered significant attention in the fields of agrochemicals, pharmaceutical intermediates, and material science. This compound, characterized by its unique chloroacetamide backbone and trifluoroethyl substituent, exhibits versatile chemical properties that make it valuable for research and industrial applications. Its molecular structure combines a chloroacetyl group with an isopropyl and a trifluoroethyl amine moiety, contributing to its reactivity and potential utility in synthetic chemistry.

In recent years, the demand for fluorinated compounds like 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide has surged due to their enhanced stability and bioavailability. Researchers are particularly interested in its role as a building block for designing novel crop protection agents and bioactive molecules. The incorporation of trifluoroethyl groups is known to improve the metabolic resistance and binding affinity of molecules, making this compound a focal point in drug discovery and agrochemical innovation.

From an environmental perspective, the compound's degradation pathways and ecotoxicological profile are critical areas of study. With increasing regulatory scrutiny on sustainable chemistry, scientists are exploring greener synthesis methods for 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide to minimize waste and energy consumption. This aligns with the global push toward green chemistry and the adoption of eco-friendly solvents in industrial processes.

The compound's CAS No. 1183184-66-8 is frequently searched in academic and industrial databases, reflecting its relevance in high-value chemical synthesis. Users often inquire about its physical properties (e.g., melting point, solubility), synthetic routes, and safety data. Analytical techniques such as NMR spectroscopy and mass spectrometry are commonly employed to characterize its purity and structural integrity, ensuring compliance with quality control standards.

In the context of patent literature, 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide has been cited in applications related to herbicide formulations and antifungal agents. Its mechanism of action often involves inhibiting key enzymatic processes in target organisms, a feature that underscores its potential for precision agriculture. As the agricultural sector seeks solutions for resistant weed management, this compound's derivatives are being evaluated for their efficacy and selectivity.

For laboratories and manufacturers, handling 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide requires adherence to good laboratory practices (GLP) and proper storage conditions to maintain stability. The compound's compatibility with other reagents and its behavior under varying pH levels are also topics of practical interest. Suppliers often provide technical datasheets detailing its handling recommendations and shelf life.

Looking ahead, the compound's applications may expand into advanced materials, such as fluorinated polymers or coatings, leveraging its chemical resistance and thermal stability. Collaborative research between academia and industry will likely drive innovations in its utilization, addressing challenges like scalability and cost-efficiency. As synthetic methodologies evolve, 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide could play a pivotal role in next-generation functional materials.

In summary, 2-chloro-N-(propan-2-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS No. 1183184-66-8) represents a multifaceted compound with broad implications across life sciences and industrial chemistry. Its unique structural features and adaptable reactivity position it as a valuable asset for researchers and manufacturers alike, particularly in the development of sustainable solutions and high-performance chemicals.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)