Cas no 1159826-67-1 (tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride)

Tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride is a protected amine derivative widely used in pharmaceutical and organic synthesis. Its key advantages include high purity and stability, making it suitable for peptide coupling and intermediate reactions. The tert-butyloxycarbonyl (Boc) group provides selective protection for the amine functionality, enabling controlled deprotection under mild acidic conditions. The hydrochloride salt enhances solubility in polar solvents, facilitating handling in aqueous or mixed-phase systems. This compound is particularly valuable in medicinal chemistry for constructing complex molecules, owing to its reliable reactivity and compatibility with standard synthetic protocols. Its well-defined structure ensures reproducibility in research and industrial applications.
tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride structure
1159826-67-1 structure
Product Name:tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride
CAS No:1159826-67-1
MF:C11H23ClN2O2
MW:250.765522241592
MDL:MFCD11101360
CID:1026083
Update Time:2025-05-19

tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride Chemical and Physical Properties

Names and Identifiers

    • tert-Butyl (piperidin-3-ylmethyl)carbamate hydrochloride
    • 2-Methyl-2-propanyl (3-piperidinylmethyl)carbamate hydrochloride (1:1)
    • 3-N-BOC-AMINOMETHYL PIPERIDINE-HCl
    • 3-N-Boc-aminomethyl piperidine HCl
    • 3-N-Boc-Aminomethyl piperidine hydrochloride
    • tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride
    • 2603AA
    • SB10247
    • AX8220126
    • ST2407624
    • AB0000766
    • B56685
    • tert-butyl N-(piperidin-3-
    • tert-butyl N-(piperidin-3-ylmethyl)carb
    • MDL: MFCD11101360
    • Inchi: 1S/C11H22N2O2.ClH/c1-11(2,3)15-10(14)13-8-9-5-4-6-12-7-9;/h9,12H,4-8H2,1-3H3,(H,13,14);1H
    • InChI Key: BIBCIACSFRCABS-UHFFFAOYSA-N
    • SMILES: Cl.O(C(NCC1CNCCC1)=O)C(C)(C)C

Computed Properties

  • Exact Mass: 250.14499
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 4
  • Complexity: 211
  • Topological Polar Surface Area: 50.4

Experimental Properties

  • PSA: 50.36

tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride Security Information

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Additional information on tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride

Introduction to Tert-butyl N-(piperidin-3-ylmethyl)carbamate Hydrochloride (CAS No. 1159826-67-1)

Tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride, a compound with the chemical identifier CAS No. 1159826-67-1, is a significant molecule in the field of pharmaceutical chemistry and biochemistry. This compound, characterized by its unique structural and functional properties, has garnered considerable attention in recent years due to its potential applications in drug development and therapeutic interventions.

The molecular structure of tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride consists of a carbamate group linked to a piperidine moiety, with a tert-butyl substituent attached to the carbamate nitrogen. This specific arrangement imparts distinct chemical and biological properties that make it a valuable candidate for various pharmacological studies. The presence of the piperidine ring enhances the compound's solubility and bioavailability, while the tert-butyl group contributes to its stability and reactivity.

In recent years, there has been growing interest in exploring the pharmacological potential of this compound. Research has indicated that tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride may exhibit inhibitory effects on certain enzymes and receptors, making it a promising candidate for the development of novel therapeutic agents. Specifically, studies have suggested that this compound could interfere with the activity of enzymes involved in pain signaling and inflammation, potentially leading to new treatments for chronic pain conditions.

One of the most compelling aspects of this compound is its ability to modulate neurological pathways. The piperidine moiety is known to interact with various neurotransmitter systems, particularly those involving dopamine and serotonin. This interaction has led researchers to investigate its potential role in treating neurological disorders such as depression, anxiety, and neurodegenerative diseases. Preliminary studies have shown that tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride may help in alleviating symptoms associated with these conditions by enhancing neurotransmitter activity.

The synthesis of tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride is another area of active research. Chemists have developed several synthetic routes to produce this compound efficiently and with high purity. These methods often involve multi-step reactions, including nucleophilic substitution and condensation reactions, followed by purification techniques such as recrystallization or column chromatography. The optimization of these synthetic pathways is crucial for ensuring that the compound is available in sufficient quantities for both laboratory research and potential clinical trials.

The pharmacokinetic properties of tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride are also subjects of extensive investigation. Researchers are studying how the compound is absorbed, distributed, metabolized, and excreted by the body. Understanding these processes is essential for determining appropriate dosages and assessing the compound's safety profile. Advanced analytical techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy have been employed to gain insights into the metabolic pathways involving this compound.

In addition to its pharmacological applications, tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride has shown promise in preclinical models as an intermediate in drug discovery programs. Its unique structural features make it a versatile building block for designing new molecules with enhanced therapeutic efficacy. By modifying various parts of its structure, researchers can fine-tune its biological activity to target specific disease mechanisms more effectively.

The regulatory landscape for tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride is also evolving as more data becomes available on its safety and efficacy. Regulatory agencies are closely monitoring ongoing clinical trials and preclinical studies to ensure that any potential therapeutic applications are thoroughly evaluated before being approved for human use. This regulatory oversight helps ensure that patients receive safe and effective treatments based on robust scientific evidence.

The future prospects for tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride appear bright, with numerous ongoing studies aimed at expanding its therapeutic applications. Researchers are exploring its potential use in treating not only neurological disorders but also other conditions such as cancer, autoimmune diseases, and metabolic disorders. As our understanding of biological systems continues to grow, it is likely that new applications for this compound will be discovered.

In conclusion, tert-butyl N-(piperidin-3-ylmethyl)carbamate hydrochloride (CAS No. 1159826-67-1) is a multifaceted compound with significant potential in pharmaceutical research and development. Its unique structural features, combined with promising preclinical results, make it a valuable asset in the quest for new therapeutic agents. As further research unfolds, it is expected that this compound will play an increasingly important role in addressing various medical challenges.

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