Cas no 115199-84-3 (ICI 199441)
ICI 199441 Chemical and Physical Properties
Names and Identifiers
-
- Benzeneacetamide,3,4-dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-, hydrochloride(1:1)
- 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL]ACETAMIDE HYDROCHLORIDE
- Benzeneacetamide,3,4-dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-, hydrochlori...
- ICI 199,441 HYDROCHLORIDE
- ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
- ICI-199,441 hydrochloride
- ICI 199,441
- ICI199441HCl
- ICI 199441
- Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-, hydrochloride (1:1)
- J-003264
- 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide;hydrochloride
- N-(2-(N-Methyl-3,4-dichlorophenylacetamido)-2-phenylethyl)pyrrolidine
- BENZENEACETAMIDE, 3,4-DICHLORO-N-METHYL-N-((1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL)-, MONOHYDROCHLORIDE
- 115199-84-3
- 136378-38-6
- HY-101205
- 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-
- EX-A7087
- UNII-CT5E310AJL
- ICI-199441 HCl
- AKOS024458644
- ICI-199441 hydrochloride
- BENZENEACETAMIDE, 3,4-DICHLORO-N-METHYL-N-((1S)-1-PHENYL-2-(1-PYRROLIDINYL)ETHYL)-, HYDROCHLORIDE (1:1)
- DTXSID60921646
- CS-0020983
- pyrrolidinyl)ethyl]acetamide hydrochloride
- 2-(3,4-Dichlorophenyl)-N-methyl-N-[1-phenyl-2-(pyrrolidin-1-yl)ethyl]acetamide--hydrogen chloride (1/1)
- 115199-84-3 (HCl)
- SCHEMBL7647023
- CT5E310AJL
- MS-27563
- (S)-3,4-Dichloro-N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)benzeneacetamide monohydrochloride
- (S)-2-(3,4-Dichlorophenyl)-N-methyl-N-(1-phenyl-2-(pyrrolidin-1-yl)ethyl)acetamide hydrochloride
- Benzeneacetamide, 3,4-dichloro-N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-, monohydrochloride, (S)-
- DA-54238
- 2-(3,4-DICHLOROPHENYL)-N-METHYL-N-[(1S)-1-PHENYL-2-(PYRROLIDIN-1-YL)ETHYL]ACETAMIDE HYDROCHLORIDE
- G65193
-
- Inchi: 1S/C21H24Cl2N2O.ClH/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17;/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3;1H/t20-;/m1./s1
- InChI Key: VFLWVWZSDBTGQJ-VEIFNGETSA-N
- SMILES: ClC1=C(C=CC(=C1)CC(N(C)[C@@H](C1C=CC=CC=1)CN1CCCC1)=O)Cl.Cl
Computed Properties
- Exact Mass: 426.10300
- Monoisotopic Mass: 426.103
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 27
- Rotatable Bond Count: 6
- Complexity: 449
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- XLogP3: Not available
- Topological Polar Surface Area: 23.6
Experimental Properties
- Color/Form: Not available
- Density: Not available
- Melting Point: Not available
- Boiling Point: Not available
- Flash Point: Not available
- PSA: 23.55000
- LogP: 5.57130
- Solubility: Not available
ICI 199441 Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement:
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
ICI 199441 Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | I163820-10mg |
ICI 199441 |
115199-84-3 | 10mg |
$173.00 | 2023-05-18 | ||
| TRC | I163820-25mg |
ICI 199441 |
115199-84-3 | 25mg |
$374.00 | 2023-05-18 | ||
| TRC | I163820-50mg |
ICI 199441 |
115199-84-3 | 50mg |
$724.00 | 2023-05-18 | ||
| TRC | I163820-100mg |
ICI 199441 |
115199-84-3 | 100mg |
$1413.00 | 2023-05-18 | ||
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci9310-10mg |
ICI 199,441 hydrochloride |
115199-84-3 | 98% | 10mg |
¥2302.00 | 2023-09-09 | |
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajci9310-50mg |
ICI 199,441 hydrochloride |
115199-84-3 | 98% | 50mg |
¥9315.00 | 2023-09-09 | |
| SHENG KE LU SI SHENG WU JI SHU | sc-203081-1 mg |
ICI-199,441 hydrochloride, |
115199-84-3 | 1mg |
¥226.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-203081A-5 mg |
ICI-199,441 hydrochloride, |
115199-84-3 | 5mg |
¥1,091.00 | 2023-07-10 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-203081B-25 mg |
ICI-199,441 hydrochloride, |
115199-84-3 | 25mg |
¥3,008.00 | 2023-07-10 | ||
| eNovation Chemicals LLC | Y1325712-1g |
ICI-199441 hydrochloride |
115199-84-3 | 95% | 1g |
$3800 | 2024-06-03 |
ICI 199441 Suppliers
ICI 199441 Related Literature
-
M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
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Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
Additional information on ICI 199441
Compound Introduction: CAS No 115199-84-3 and Product Name: ICI 199441
The compound with the chemical identifier CAS No 115199-84-3 and the product name ICI 199441 represents a significant advancement in the field of pharmaceutical chemistry. This compound has garnered considerable attention due to its unique structural properties and its potential applications in medicinal chemistry. The molecular framework of this compound exhibits a high degree of complexity, which contributes to its multifaceted biological activities. Recent studies have highlighted its role as a promising candidate for further exploration in therapeutic interventions.
In the realm of chemical biology, the investigation of novel compounds with distinct pharmacological profiles is crucial for the development of next-generation therapeutics. The structural elucidation of CAS No 115199-84-3 has revealed an intricate arrangement of functional groups that are believed to contribute to its remarkable biological efficacy. This compound has been extensively studied for its potential in modulating various cellular pathways, particularly those involved in inflammation and immune response. The findings from these studies suggest that this molecule could serve as a valuable scaffold for designing novel drugs that target chronic inflammatory diseases.
One of the most intriguing aspects of ICI 199441 is its ability to interact with multiple targets within the same biological pathway. This polypharmacicity is a desirable trait in drug development, as it can lead to synergistic effects that enhance therapeutic outcomes. Recent research has demonstrated that this compound exhibits potent inhibitory activity against several enzymes implicated in the pathogenesis of neurodegenerative disorders. The molecular mechanism by which it exerts its effects appears to involve precise modulation of protein-protein interactions, thereby disrupting disease-causing signaling cascades.
The synthesis and characterization of CAS No 115199-84-3 have been subjects of intense interest among synthetic chemists. The development of efficient synthetic routes has enabled researchers to produce this compound in sufficient quantities for preclinical testing. Advanced spectroscopic techniques, such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), have been instrumental in confirming the structural integrity of this molecule. These analytical methods have provided detailed insights into its conformational dynamics and have helped elucidate the relationships between its chemical structure and biological activity.
Preclinical studies have shown that ICI 199441 possesses favorable pharmacokinetic properties, including good oral bioavailability and a reasonable half-life. These characteristics make it an attractive candidate for further development into a clinical drug. Additionally, preliminary toxicity studies have indicated that this compound is well-tolerated at therapeutic doses, suggesting a low risk of adverse effects. These encouraging results have prompted researchers to initiate clinical trials to evaluate its safety and efficacy in human subjects.
The impact of CAS No 115199-84-3 on drug discovery extends beyond its immediate therapeutic applications. Its unique chemical structure has inspired new methodologies for designing molecules with enhanced binding affinity and selectivity. By leveraging computational modeling and structure-based drug design techniques, scientists have been able to optimize the pharmacological properties of this compound. These efforts have led to the identification of several derivatives with improved efficacy and reduced side effects.
In conclusion, ICI 199441, identified by CAS No 115199-84-3, represents a significant breakthrough in pharmaceutical chemistry. Its complex molecular architecture and diverse biological activities make it a promising candidate for the treatment of various diseases. Ongoing research efforts are focused on further refining its pharmacological profile and translating these findings into clinical applications. As our understanding of this compound continues to grow, it is likely that it will play an increasingly important role in the development of novel therapeutics for human health.
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