Cas no 114676-59-4 (H-cis-Hyp-OMe.HCl)

H-cis-Hyp-OMe·HCl is a protected derivative of hydroxyproline, commonly used in peptide synthesis and pharmaceutical research. The cis-configuration of the hydroxyproline moiety provides structural specificity, making it valuable for studying collagen-like peptides and bioactive compounds. The methyl ester (OMe) and hydrochloride (HCl) modifications enhance solubility and stability, facilitating handling and purification. This compound is particularly useful in solid-phase peptide synthesis (SPPS) due to its compatibility with standard protecting group strategies. Its precise stereochemistry ensures reproducibility in constructing complex peptide architectures, supporting applications in drug development and biochemical studies. High purity and consistent quality make it a reliable choice for researchers.
H-cis-Hyp-OMe.HCl structure
H-cis-Hyp-OMe.HCl structure
Product Name:H-cis-Hyp-OMe.HCl
CAS No:114676-59-4
MF:C6H11NO3.HCl
MW:181.61738
MDL:MFCD00082536
CID:130415
PubChem ID:12764090
Update Time:2025-06-07

H-cis-Hyp-OMe.HCl Chemical and Physical Properties

Names and Identifiers

    • (2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
    • (2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate HCl
    • D- Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-
    • Methyl (2R,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride
    • D-Proline, 4-Hydroxy
    • Cis-4-Hydroxy-D-proline Methyl ester HCl
    • Methyl 4-hydroxypyrrolidine-2-carboxylate HCl
    • Cis-4-hydroxy-proline Methyl ester hydrochloride -D-
    • D-Proline, 4-hydroxy-, Methyl ester, hydrochloride, (4R)-
    • (2R,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester hydrochloride
    • (2R,4R)-4-Hydroxy-2-(methoxycarbonyl)pyrrolidine hydrochloride, cis-4-Hydroxy-D-proline methyl ester hydrochloride
    • D-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-
    • HY-76105
    • SCHEMBL475806
    • (2R,4R)-4-hydroxy-2-methoxycarbonylpyrrolidine hydrochloride
    • EN300-108156
    • 4-(R)-Hydroxypyrrolidine-2-(R)-carboxylic acid methyl ester hydrochloride
    • 114676-59-4
    • KLGSHNXEUZOKHH-TYSVMGFPSA-N
    • 4-Hydroxy-D-proline methyl ester hydrochloride
    • AS-20028
    • cis-4-Hydroxy-D-proline methyl ester hydrochloride, AldrichCPR
    • CS-M0680
    • (2R,4R)-METHYL4-HYDROXYPYRROLIDINE-2-CARBOXYLATEHYDROCHLORIDE
    • AKOS000278312
    • AKOS005257105
    • AC-32545
    • D-Proline, 4-hydroxy-, methyl ester (hydrochloride)
    • (2R,4R)-4-Hydroxy-pyrrolidine-2-carboxylic acid methyl ester hydrochloride
    • cis-4-Hydroxy-D-proline methyl ester hydrochloride
    • methyl (2R,4R)-4-hydroxypyrrolidine-2-carboxylate;hydrochloride
    • MFCD00082536
    • H-cis-Hyp-OMe.HCl
    • MDL： MFCD00082536
    • Inchi： InChI=1S/C6H11NO3.ClH/c1-10-6(9)5-2-4(8)3-7-5;/h4-5,7-8H,2-3H2,1H3;1H/t4-,5-;/m1./s1
    • InChI Key： KLGSHNXEUZOKHH-TYSVMGFPSA-N
    • SMILES： COC(=O)[C@H]1C[C@H](CN1)O.Cl

Computed Properties

  • Exact Mass: 181.0505709g/mol
  • Monoisotopic Mass: 181.0505709g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 137
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 58.6?2

Experimental Properties

  • Color/Form: White to Yellow Solid
  • Melting Point: 121-123 oC
  • PSA: 58.56000
  • LogP: 0.01300

H-cis-Hyp-OMe.HCl Security Information

H-cis-Hyp-OMe.HCl Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
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(2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
 114676-59-4 97%
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 $283.25 2023-09-04
Alichem
A109006049-100g
(2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
 114676-59-4 97%
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Fluorochem
217039-5g
2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
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Fluorochem
217039-10g
2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
 114676-59-4 95%
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 ￡44.00 2022-03-01
Fluorochem
217039-25g
2R,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
 114676-59-4 95%
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 ￡82.00 2022-03-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
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H-cis-Hyp-OMe.HCl
 114676-59-4 97%
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 ￥51.90 2023-09-01
AstaTech
62580-5/G
METHYL (2R,4R)-4-HYDROXYPYRROLIDINE-2-CARBOXYLATE HYDROCHLORIDE
 114676-59-4 97%
5g
 $56 2023-09-16
AstaTech
62580-25/G
METHYL (2R,4R)-4-HYDROXYPYRROLIDINE-2-CARBOXYLATE HYDROCHLORIDE
 114676-59-4 97%
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AstaTech
62580-100/G
METHYL (2R,4R)-4-HYDROXYPYRROLIDINE-2-CARBOXYLATE HYDROCHLORIDE
 114676-59-4 97%
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 $420 2023-09-16

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