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  Sandip Gangadhar Balwe,Yeon Tae Jeong Org. Biomol. Chem., 2018,16, 1287-1296
• 2. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 3. An alkynylboronatecycloaddition strategy to functionalised benzyne derivatives?
  James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
• 4. An assessment of strategies for the development of solid-state adsorbents for vehicular hydrogen storage
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzonitriles

Comprehensive Overview of 4-(Imidazol-1-ylmethyl)benzonitrile (CAS No. 112809-54-8): Properties, Applications, and Industry Insights

4-(Imidazol-1-ylmethyl)benzonitrile (CAS No. 112809-54-8) is a specialized organic compound featuring a unique molecular structure combining an imidazole ring and a benzonitrile moiety. This hybrid structure grants it versatile chemical properties, making it valuable in pharmaceutical research, material science, and agrochemical development. The compound's imidazole-1-ylmethyl group enhances its reactivity, while the cyano functionality offers opportunities for further derivatization, aligning with modern structure-activity relationship (SAR) studies.

In recent years, the demand for imidazole-based compounds like 4-(Imidazol-1-ylmethyl)benzonitrile has surged due to their role in designing kinase inhibitors and antifungal agents. Researchers frequently explore its potential in drug discovery, particularly for targeting enzyme modulation and receptor binding. Its CAS No. 112809-54-8 is often cited in patent literature, reflecting its industrial relevance. A growing trend in green chemistry has also spurred interest in optimizing its synthesis routes to reduce environmental impact.

The compound's physicochemical properties—such as moderate solubility in polar solvents and stability under ambient conditions—make it suitable for high-throughput screening (HTS) applications. Analytical techniques like HPLC and NMR are commonly employed to verify its purity, a critical factor for pharmaceutical intermediates. Users searching for "4-(Imidazol-1-ylmethyl)benzonitrile supplier" or "CAS 112809-54-8 synthesis protocol" often seek details on scalable production methods, reflecting market needs.

Beyond pharmaceuticals, 4-(Imidazol-1-ylmethyl)benzonitrile finds niche applications in advanced material synthesis, including coordination polymers and ligand design for catalysis. Its nitrile group allows covalent bonding with metal surfaces, a feature exploited in surface modification technologies. Discussions on platforms like ResearchGate highlight its utility in cross-coupling reactions, a hot topic in organic chemistry forums.

From an SEO perspective, queries such as "imidazole derivatives in drug development" or "benzonitrile applications 2024" align with this compound's profile. Addressing these trends, this article emphasizes real-world relevance while maintaining technical rigor. For instance, the rise of AI-driven molecular modeling has increased interest in small-molecule libraries containing CAS 112809-54-8, underscoring its role in computational chemistry workflows.

Quality control remains a priority for manufacturers of 4-(Imidazol-1-ylmethyl)benzonitrile. Specifications like ≥98% purity and residual solvent limits are frequently requested in procurement documents. Regulatory compliance with REACH and FDA guidelines further elevates its standing in GMP-certified supply chains. These factors contribute to its prominence in life science databases like PubChem and SciFinder.

In conclusion, 4-(Imidazol-1-ylmethyl)benzonitrile (CAS No. 112809-54-8) exemplifies the intersection of innovation and practical utility in fine chemicals. Its adaptability across biomedical and material science domains ensures sustained interest, while evolving synthetic methodologies promise expanded applications. This aligns with broader industry shifts toward sustainable and multifunctional chemical solutions.

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• 143426-58-8(2-(1H-imidazol-1-yl)methylbenzonitrile)
• 143426-59-9(3-(1H-imidazol-1-yl)methylbenzonitrile)
• 56643-83-5(bimb)
• 52461-82-2(1H-Imidazolium, 1-methyl-3-(phenylmethyl)-)
• 112809-31-1(4-[1-(1H-imidazol-1-yl)ethyl]-Benzonitrile)
• 1345412-19-2(4-(1H-imidazol-1-yl)methyl-2-methylbenzonitrile)
• 112086-47-2([4-(imidazol-1-ylmethyl)phenyl]methanamine)
• 78430-91-8(1-(4-Vinylbenzyl)-1H-imidazole)