- Selective Nickel-Catalyzed Hydrodeacetoxylation of Aryl AcetatesBy De Smet, Gilles et al, Angewandte Chemie, 2022, 61(38), e202201751
Cas no 1126-93-8 (2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane)
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a highly stable and versatile boronic ester compound, widely used as a key intermediate in organic synthesis and cross-coupling reactions. Its structure features a protected boronic acid moiety, which enhances stability against moisture and oxidation compared to free boronic acids. This compound is particularly valuable in Suzuki-Miyaura coupling reactions, enabling efficient carbon-carbon bond formation under mild conditions. The ethoxy group improves solubility in organic solvents, facilitating handling and reaction optimization. Its crystalline solid form ensures high purity and ease of storage. Due to its reliability and compatibility with diverse substrates, it is a preferred choice for pharmaceutical and materials science research.
1126-93-8 structure
Product Name:2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No:1126-93-8
MF:C8H17BO3
MW:172.029783010483
MDL:MFCD22054335
CID:821386
PubChem ID:253659817
Update Time:2025-07-02
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Chemical and Physical Properties
Names and Identifiers
-
- 1,3,2-Dioxaborolane, 2-ethoxy-4,4,5,5-tetramethyl
- 2-Ethoxy-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
- 1,3,2-Dioxaborolane, 2-ethoxy-4,4,5,5-tetramethyl-
- 2-Aethoxy-4,4,5,5,-tetramethyl-1,3,2-dioxaborolan
- 2-ethoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
- 2-Ethoxy-4.4.5.5-tetramethyl-1.3.2-dioxaborolan
- ACT08947
- CTK0G1443
- ethyl pinacol borate
- Ethyl-1,1,2,2-tetramethyl-ethylen-borat
- SureCN6493277
- X7232
- Ethoxyboronic Acid Pinacol Ester
- 2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaboralane
- C8H17BO3
- E0982
- D80491
- AKOS037644952
- MFCD22054335
- AS-55616
- 1126-93-8
- SCHEMBL6493277
- SY053310
- CS-0151942
- DTXSID60508219
- 2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
-
- MDL： MFCD22054335
- Inchi： 1S/C8H17BO3/c1-6-10-9-11-7(2,3)8(4,5)12-9/h6H2,1-5H3
- InChI Key： AWCHCIVACATJJS-UHFFFAOYSA-N
- SMILES： O1B(OCC)OC(C)(C)C1(C)C
Computed Properties
- Exact Mass: 171.13071
- Monoisotopic Mass: 172.1270746g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 2
- Complexity: 152
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 27.7
Experimental Properties
- Density: 0.93
- Boiling Point: 32°C/5.3mmHg(lit.)
- Flash Point: 15 oC
- Refractive Index: 1.4070-1.4110
- PSA: 27.69
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Security Information
-
Symbol:
- Prompt：warning
- Hazard Statement： H226
- Warning Statement： P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
- Hazardous Material transportation number：1993
- HazardClass：3
- PackingGroup：III
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | E0982-25G |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | >97.0%(GC)(T) | 25g |
￥545.00 | 2024-04-18 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E156077-25G |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 95% | 25g |
￥688.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E156077-5G |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 95% | 5g |
￥153.90 | 2023-09-03 | |
| TRC | E893080-50mg |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 50mg |
$ 50.00 | 2022-06-05 | ||
| TRC | E893080-100mg |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 100mg |
$ 65.00 | 2022-06-05 | ||
| TRC | E893080-500mg |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 500mg |
$ 80.00 | 2022-06-05 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | E862836-5g |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | ≥97%(GC)(T) | 5g |
￥211.50 | 2022-01-11 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | E862836-1g |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | ≥97%(GC)(T) | 1g |
￥61.20 | 2022-01-11 | |
| Apollo Scientific | OR919768-5g |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 95% | 5g |
￡110.00 | 2023-09-02 | |
| Apollo Scientific | OR919768-25g |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane |
1126-93-8 | 95% | 25g |
￡239.00 | 2025-02-20 |
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Production Method
Production Method 1
Reaction Conditions
1.1C:Ni dicyclooctadiene, C:258278-28-3, S:(MeO)2CO, 1 h, 25°C
1.224 h, 85°C; 85°C → rt
1.3R:H2O
1.224 h, 85°C; 85°C → rt
1.3R:H2O
Reference
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Raw materials
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Preparation Products
2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Related Literature
-
Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
-
Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
-
Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
1126-93-8 (2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane) Related Products
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