• 1. Evolution of shape, size, and areal density of a single plane of Si nanocrystals embedded in SiO2 matrix studied by atom probe tomography
  Bin Han,Yasuo Shimizu,Gabriele Seguini,Celia Castro,Gérard Ben Assayag,Koji Inoue,Yasuyoshi Nagai,Sylvie Schamm-Chardon,Michele Perego RSC Adv., 2016,6, 3617-3622
• 2. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
• 3. Distribution and ecological risk assessment of typical antibiotics in the surface waters of seven major rivers, China?
  Environ. Sci.: Processes Impacts, 2021,23, 1088-1100
• 4. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 5. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives N-acyl-alpha amino acids
• Solvents and Organic Chemicals Organic Compounds Acids/Esters

N-Acetyl-DL-alanine (CAS No. 1115-69-1): An Overview of Its Properties, Applications, and Recent Research

N-Acetyl-DL-alanine (CAS No. 1115-69-1) is a versatile compound with significant applications in various fields, including pharmaceuticals, biochemistry, and materials science. This compound is a derivative of alanine, an essential amino acid, and is characterized by its acetylated amino group. The acetylation process modifies the chemical properties of alanine, making it more stable and less prone to degradation in certain environments.

The chemical structure of N-Acetyl-DL-alanine consists of a central carbon atom bonded to an acetyl group (-COCH3), an amino group (-NH2), and a carboxyl group (-COOH). The DL designation indicates that the compound is a racemic mixture of both the L (levo) and D (dextro) enantiomers. This racemic nature provides flexibility in its use across different applications, as it can be easily converted to either enantiomer through chiral resolution techniques.

In the pharmaceutical industry, N-Acetyl-DL-alanine has gained attention for its potential therapeutic applications. Recent studies have explored its use as a precursor in the synthesis of more complex molecules with medicinal properties. For instance, it has been utilized in the development of prodrugs that are designed to enhance the bioavailability and efficacy of active pharmaceutical ingredients (APIs). The acetylated form of alanine can help improve the solubility and stability of these prodrugs, making them more suitable for oral administration.

Beyond pharmaceuticals, N-Acetyl-DL-alanine has found applications in biochemistry research. It serves as a valuable tool for studying protein structure and function due to its ability to mimic certain aspects of natural amino acids. Researchers have used this compound to investigate protein folding mechanisms and to design peptides with specific biological activities. The stability and reactivity of N-Acetyl-DL-alanine make it an ideal candidate for such studies.

In materials science, N-Acetyl-DL-alanine has been explored for its potential in the development of functional materials. Its unique chemical properties allow it to be incorporated into polymers and other materials to enhance their performance. For example, recent studies have shown that incorporating N-Acetyl-DL-alanine into polymer matrices can improve their mechanical strength and thermal stability. This makes it a promising candidate for applications in advanced materials such as biodegradable plastics and drug delivery systems.

The safety profile of N-Acetyl-DL-alanine is another important aspect that has been extensively studied. It is generally considered safe for use in various applications, with minimal toxicity concerns. However, like any chemical compound, proper handling and storage protocols should be followed to ensure safety. Recent safety assessments have confirmed its low toxicity and non-irritant properties, making it suitable for use in both laboratory and industrial settings.

In conclusion, N-Acetyl-DL-alanine (CAS No. 1115-69-1) is a multifaceted compound with a wide range of applications across pharmaceuticals, biochemistry, and materials science. Its unique chemical properties make it a valuable tool for researchers and developers working on innovative solutions in these fields. As ongoing research continues to uncover new possibilities, the importance of N-Acetyl-DL-alanine is likely to grow even further.

• 97-14-3(N-Acetyl-DL-serine)
• 220254-53-5(Alanine, glycylglycyl-, free radical from (9CI))
• 20347-80-2(L-Alanine,glycylglycylglycylglycyl-)
• 16354-58-8(N-Acetyl-L-serine (>90%))
• 110294-55-8(Dismutase, superoxide(human clone pS61-10 copper-zinc subunit protein moiety reduced) N-acetyl-(9CI))
• 53846-71-2(SAR-ALA-OH)
• 97-69-8((2S)-2-acetamidopropanoic acid)
• 19729-30-7(H-Gly-Gly-Ala-OH)
• 19436-52-3(Ac-D-Ala-OH)
• 220254-49-9(Alanine,N-acetylglycyl-, free radical from (9CI))