• 1. An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement?
  Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
• 2. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
  Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
• 3. An artificial photosynthetic system for photoaccumulation of two electrons on a fused dipyridophenazine (dppz)–pyridoquinolinone ligand?
  Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
• 4. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?
  Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455
• 5. An antimonate pyrochlore (H1.23Sr0.45SbO3.48) for photocatalytic oxidation of benzene: effective oxygen usage and excellent activity?
  Jing Chen,Yu Shao,Danzhen Li J. Mater. Chem. A, 2017,5, 937-941

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Dimethoxybenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Methoxybenzenes Dimethoxybenzenes

Comprehensive Overview of (5-Amino-2,3-dimethoxyphenyl)methanol (CAS No. 1111236-54-4): Properties, Applications, and Industry Insights

(5-Amino-2,3-dimethoxyphenyl)methanol, identified by its CAS number 1111236-54-4, is a specialized organic compound gaining attention in pharmaceutical and chemical research. This aromatic derivative features a methanol group attached to a dimethoxyphenyl ring, further substituted with an amino group at the 5-position. Its unique molecular structure makes it a valuable intermediate in synthesizing complex molecules, particularly in drug discovery and material science.

The compound's chemical properties include moderate solubility in polar organic solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO), while being less soluble in water. Its amino and hydroxyl functional groups enable diverse chemical modifications, making it versatile for cross-coupling reactions and protecting group strategies. Researchers often explore its potential in developing central nervous system (CNS) therapeutics, given the structural resemblance to bioactive alkaloids.

In recent years, 1111236-54-4 has emerged in discussions about green chemistry and sustainable synthesis. With growing interest in eco-friendly catalysts and reduced waste production, this compound's role in atom-efficient reactions is being investigated. Its dimethoxy motif is particularly relevant to natural product synthesis, aligning with trends in biomimetic chemistry.

From a commercial perspective, the demand for (5-Amino-2,3-dimethoxyphenyl)methanol correlates with advancements in high-throughput screening and combinatorial chemistry. Suppliers often highlight its high purity grades (≥95%–98%) for research applications. Analytical techniques like HPLC, NMR spectroscopy, and mass spectrometry are critical for quality control, addressing the pharmaceutical industry's stringent standards.

Frequently searched questions include: "How to synthesize (5-Amino-2,3-dimethoxyphenyl)methanol?", "CAS 1111236-54-4 safety data", and "Applications in medicinal chemistry". These reflect user priorities around synthetic protocols, handling precautions, and therapeutic potential. Notably, the compound's logP value (predicting lipophilicity) and hydrogen bonding capacity are key parameters for drug designers optimizing bioavailability.

Emerging studies explore its derivatives for neuroprotective agents and enzyme inhibitors, tapping into markets focused on neurodegenerative diseases. The 2,3-dimethoxy pattern is also significant in flavonoid analogs, linking to antioxidant research—a trending topic in nutraceuticals and anti-aging formulations.

For SEO optimization, this content integrates semantically related terms like "aromatic amino alcohols", "multifunctional intermediates", and "small molecule building blocks". Such terminology aligns with how researchers and procurement specialists search for specialized chemicals. The compound's regulatory status (non-hazardous under standard conditions) further enhances its accessibility for industrial applications.

In conclusion, CAS 1111236-54-4 represents a structurally versatile scaffold with expanding relevance across life sciences and material engineering. Its dual methoxy and amino functionalities offer synthetic flexibility, while ongoing research continues to uncover novel applications—from catalysis to bioimaging probes. As innovation drives demand for tailored molecular platforms, this compound remains a noteworthy candidate in cutting-edge chemistry.

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