Cas no 110945-00-1 (2-chloro-1-4-(dimethylamino)phenylethan-1-one)
2-chloro-1-4-(dimethylamino)phenylethan-1-one Chemical and Physical Properties
Names and Identifiers
-
- Ethanone,2-chloro-1-[4-(dimethylamino)phenyl]-
- Ethanone, 2-chloro-1-[4-(dimethylamino)phenyl]- (9CI)
- 2-chloro-1-[4-(dimethylamino)phenyl]ethanone
- 2-CHLORO-4'-(DIMETHYLAMINO)ACETOPHENONE
- 2-Chloro-1-(4-(dimethylamino)phenyl)ethanone
- 2-chloro-1-4-(dimethylamino)phenylethan-1-one
- 110945-00-1
- MFCD08059551
- EN300-1965212
- Ethanone,2-chloro-1-[4-(dimethylamino)phenyl]-(9CI)
- 2-Chloro-1-[4-(dimethylamino)phenyl]ethan-1-one
- 2-chloro-1-(4-dimethylaminophenyl)ethanone
- SCHEMBL4187495
- AKOS022278649
- Ethanone, 2-chloro-1-(4-(dimethylamino)phenyl)-
- DTXSID20149425
- 4-(N,N-Dimethylamino)phenacyl bromide
- InChI=1/C10H12ClNO/c1-12(2)9-5-3-8(4-6-9)10(13)7-11/h3-6H,7H2,1-2H
- Ethanone, 2-chloro-1-[4-(dimethylamino)phenyl]-
- DB-276520
- 4-(N,N-Dimethylamino)phenacyl chloride
- DTXCID0071916
-
- MDL: MFCD08059551
- Inchi: 1S/C10H12ClNO/c1-12(2)9-5-3-8(4-6-9)10(13)7-11/h3-6H,7H2,1-2H3
- InChI Key: ONHGPIBFTKDBHT-UHFFFAOYSA-N
- SMILES: ClCC(C1C=CC(=CC=1)N(C)C)=O
Computed Properties
- Exact Mass: 197.06086
- Monoisotopic Mass: 197.0607417g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 174
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.7
- Topological Polar Surface Area: 20.3?2
Experimental Properties
- PSA: 20.31
2-chloro-1-4-(dimethylamino)phenylethan-1-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| abcr | AB246804-1 g |
4-(N,N-Dimethylamino)phenacyl bromide |
110945-00-1 | 1g |
€783.00 | 2023-06-22 | ||
| Alichem | A019116552-1g |
2-Chloro-1-(4-(dimethylamino)phenyl)ethanone |
110945-00-1 | 97% | 1g |
$588.00 | 2023-09-04 | |
| Alichem | A019116552-5g |
2-Chloro-1-(4-(dimethylamino)phenyl)ethanone |
110945-00-1 | 97% | 5g |
$2056.40 | 2023-09-04 | |
| Enamine | EN300-1965212-0.05g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 0.05g |
$768.0 | 2023-09-17 | ||
| Enamine | EN300-1965212-0.1g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 0.1g |
$804.0 | 2023-09-17 | ||
| Enamine | EN300-1965212-0.25g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 0.25g |
$840.0 | 2023-09-17 | ||
| Enamine | EN300-1965212-0.5g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 0.5g |
$877.0 | 2023-09-17 | ||
| Enamine | EN300-1965212-1.0g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 1g |
$914.0 | 2023-06-02 | ||
| Enamine | EN300-1965212-2.5g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 2.5g |
$1791.0 | 2023-09-17 | ||
| Enamine | EN300-1965212-5.0g |
2-chloro-1-[4-(dimethylamino)phenyl]ethan-1-one |
110945-00-1 | 5g |
$2650.0 | 2023-06-02 |
2-chloro-1-4-(dimethylamino)phenylethan-1-one Suppliers
2-chloro-1-4-(dimethylamino)phenylethan-1-one Related Literature
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Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
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Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
Additional information on 2-chloro-1-4-(dimethylamino)phenylethan-1-one
Introduction to 2-Chloro-1-(4-(Dimethylamino)phenyl)ethan-1-one (CAS No. 110945-00-1)
2-Chloro-1-(4-(dimethylamino)phenyl)ethan-1-one, also known by its CAS number 110945-00-1, is a versatile organic compound that has garnered significant attention in the fields of medicinal chemistry and materials science. This compound is characterized by its unique structure, which includes a chloro-substituted ethanone moiety and a dimethylamino group attached to a phenyl ring. The combination of these functional groups imparts distinct chemical and physical properties, making it a valuable intermediate in various synthetic processes.
The chloro-substituted ethanone moiety in 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one is particularly noteworthy due to its reactivity and versatility. This functional group can undergo a variety of chemical transformations, such as nucleophilic substitution reactions, which are crucial in the synthesis of more complex molecules. Additionally, the presence of the dimethylamino group on the phenyl ring enhances the compound's basicity and polarity, which can influence its solubility and reactivity in different solvents.
Recent research has highlighted the potential applications of 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one in the development of novel pharmaceuticals. For instance, studies have shown that this compound can serve as a key intermediate in the synthesis of drugs targeting specific biological pathways. One notable example is its use in the preparation of compounds with anti-inflammatory and analgesic properties. The ability to fine-tune the structure of these derivatives through strategic modifications has opened up new avenues for drug discovery and development.
In the realm of materials science, 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one has also demonstrated promising properties. Its unique combination of functional groups makes it suitable for use in the synthesis of advanced materials with tailored optical and electronic characteristics. For example, researchers have explored its potential as a building block for organic semiconductors and luminescent materials. These materials have applications in areas such as organic light-emitting diodes (OLEDs) and photovoltaic devices.
The synthesis of 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one typically involves multi-step processes that require precise control over reaction conditions. Common synthetic routes include the condensation of 4-dimethylaminobenzaldehyde with chloroacetyl chloride followed by subsequent purification steps. Advances in catalytic methods have further optimized these processes, leading to higher yields and improved product purity.
From a safety perspective, it is important to handle 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one with care due to its reactivity and potential health effects. Proper personal protective equipment (PPE), such as gloves and goggles, should be worn during handling, and work should be conducted in well-ventilated areas or fume hoods to minimize exposure risks.
In conclusion, 2-chloro-1-(4-(dimethylamino)phenyl)ethan-1-one (CAS No. 110945-00-1) is a multifaceted compound with a wide range of applications in medicinal chemistry and materials science. Its unique structural features make it an invaluable intermediate in various synthetic processes, contributing to advancements in drug discovery, material development, and beyond. As research continues to uncover new possibilities for this compound, its importance in the scientific community is likely to grow even further.
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