Cas no 1095075-62-9 (N-(Butan-2-YL)-N-ethylsulfamoyl chloride)

N-(Butan-2-yl)-N-ethylsulfamoyl chloride is a sulfamoyl chloride derivative used as a versatile intermediate in organic synthesis, particularly in the preparation of sulfonamides. Its reactive sulfamoyl chloride group enables efficient nucleophilic substitution reactions with amines, alcohols, and other nucleophiles, facilitating the introduction of sulfonamide functionalities. The compound’s branched alkyl substituents (butan-2-yl and ethyl) may influence solubility and steric properties, making it suitable for tailored synthetic applications. It is typically handled under anhydrous conditions due to its moisture sensitivity. This reagent is valued for its role in medicinal chemistry and agrochemical research, where sulfonamide derivatives are often key structural motifs.
N-(Butan-2-YL)-N-ethylsulfamoyl chloride structure
1095075-62-9 structure
Product Name:N-(Butan-2-YL)-N-ethylsulfamoyl chloride
CAS No:1095075-62-9
MF:C6H14ClNO2S
MW:199.69885969162
CID:5156870
PubChem ID:43274429
Update Time:2025-05-24

N-(Butan-2-YL)-N-ethylsulfamoyl chloride Chemical and Physical Properties

Names and Identifiers

    • N-(BUTAN-2-YL)-N-ETHYLSULFAMOYL CHLORIDE
    • Sec-butyl(ethyl)sulfamoyl chloride
    • N-(BUTAN-2-YL)-N-ETHYLSULFAMOYLCHLORIDE
    • Sulfamoyl chloride, N-ethyl-N-(1-methylpropyl)-
    • N-(Butan-2-YL)-N-ethylsulfamoyl chloride
    • Inchi: 1S/C6H14ClNO2S/c1-4-6(3)8(5-2)11(7,9)10/h6H,4-5H2,1-3H3
    • InChI Key: LOCKLDFTXGPYDR-UHFFFAOYSA-N
    • SMILES: ClS(N(CC)C(C)CC)(=O)=O

Computed Properties

  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 4
  • Complexity: 197
  • XLogP3: 2
  • Topological Polar Surface Area: 45.8

N-(Butan-2-YL)-N-ethylsulfamoyl chloride Pricemore >>

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Additional information on N-(Butan-2-YL)-N-ethylsulfamoyl chloride

Comprehensive Overview of N-(Butan-2-YL)-N-ethylsulfamoyl chloride (CAS No. 1095075-62-9)

N-(Butan-2-YL)-N-ethylsulfamoyl chloride (CAS No. 1095075-62-9) is a specialized sulfamoyl chloride derivative widely utilized in organic synthesis and pharmaceutical research. This compound belongs to the class of sulfonamide-based intermediates, which are pivotal in constructing complex molecular architectures. Its unique structure, featuring a butan-2-yl group and an ethyl substituent, makes it a versatile reagent for introducing sulfamoyl functionalities into target molecules. Researchers and industries value this compound for its role in developing high-performance materials and bioactive molecules.

In recent years, the demand for sulfamoyl chloride derivatives like N-(Butan-2-YL)-N-ethylsulfamoyl chloride has surged due to their applications in drug discovery and agrochemical innovation. With the rise of green chemistry and sustainable synthesis, this compound has garnered attention for its potential in reducing waste and improving reaction efficiency. Its compatibility with catalytic processes and microwave-assisted reactions aligns with modern trends toward energy-efficient methodologies.

The synthesis of N-(Butan-2-YL)-N-ethylsulfamoyl chloride involves carefully controlled reactions to ensure high purity and yield. Analytical techniques such as NMR spectroscopy, HPLC, and mass spectrometry are employed to validate its structural integrity. This compound's stability under inert conditions makes it suitable for long-term storage, a critical factor for laboratory reagents and industrial-scale applications.

One of the most searched questions related to sulfamoyl chlorides is their role in peptide modification and protein engineering. N-(Butan-2-YL)-N-ethylsulfamoyl chloride is particularly noted for its ability to introduce sulfonamide groups into amino acid side chains, enabling the development of customized biomolecules. This application is highly relevant in bioconjugation and therapeutic agent design, areas that dominate current scientific discourse.

From an industrial perspective, N-(Butan-2-YL)-N-ethylsulfamoyl chloride is instrumental in producing specialty chemicals and advanced polymers. Its reactivity with nucleophiles allows for the creation of sulfonamide-linked polymers, which exhibit enhanced thermal and chemical resistance. These materials are increasingly used in electronics, coatings, and adhesives, addressing the growing need for high-performance industrial solutions.

Safety and handling protocols for N-(Butan-2-YL)-N-ethylsulfamoyl chloride emphasize the use of personal protective equipment (PPE) and proper ventilation. While it is not classified under restricted categories, adherence to good laboratory practices (GLP) ensures safe usage. This aligns with the broader industry focus on occupational health and environmental responsibility, topics frequently explored in scientific forums and regulatory guidelines.

In summary, N-(Butan-2-YL)-N-ethylsulfamoyl chloride (CAS No. 1095075-62-9) is a multifaceted compound with significant implications across pharmaceuticals, materials science, and biotechnology. Its adaptability to modern synthetic strategies and alignment with sustainability goals make it a valuable asset for researchers and manufacturers alike. As the scientific community continues to explore its potential, this compound is poised to play an even greater role in innovative chemical solutions.

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