Cas no 1092461-19-2 (5-Chloro-2-(trifluoromethoxy)benzyl bromide)
5-Chloro-2-(trifluoromethoxy)benzyl bromide is a versatile halogenated aromatic compound, primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its key structural features include a benzyl bromide moiety and a chloro-trifluoromethoxy substitution pattern, which enhance its reactivity in nucleophilic substitution and cross-coupling reactions. The trifluoromethoxy group contributes to increased lipophilicity and metabolic stability, making it valuable in the development of bioactive molecules. This compound is particularly useful in constructing complex scaffolds for agrochemicals, pharmaceuticals, and specialty materials. Its high purity and consistent reactivity ensure reliable performance in synthetic applications. Proper handling under inert conditions is recommended due to its sensitivity to moisture and light.
1092461-19-2 structure
Product Name:5-Chloro-2-(trifluoromethoxy)benzyl bromide
CAS No:1092461-19-2
MF:C8H5BrClF3O
MW:289.476911306381
MDL:MFCD11519358
CID:3161386
PubChem ID:57372372
Update Time:2025-10-14
5-Chloro-2-(trifluoromethoxy)benzyl bromide Chemical and Physical Properties
Names and Identifiers
-
- 5-Chloro-2-(trifluoromethoxy)benzyl bromide
- 2-(bromomethyl)-4-chloro-1-(trifluoromethoxy)benzene
- MFCD11519358
- SCHEMBL21266901
- JS-4866
- CS-0440608
- NVZXASWBNNGRKE-UHFFFAOYSA-N
- 1092461-19-2
- DB-163366
- AKOS015956720
-
- MDL： MFCD11519358
- Inchi： 1S/C8H5BrClF3O/c9-4-5-3-6(10)1-2-7(5)14-8(11,12)13/h1-3H,4H2
- InChI Key： NVZXASWBNNGRKE-UHFFFAOYSA-N
- SMILES： BrCC1C=C(C=CC=1OC(F)(F)F)Cl
Computed Properties
- Exact Mass: 287.916
- Monoisotopic Mass: 287.916
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 14
- Rotatable Bond Count: 3
- Complexity: 188
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 9.2A^2
- XLogP3: 4.3
Experimental Properties
- Density: 1.7±0.1 g/cm3
- Boiling Point: 226.1±35.0 °C at 760 mmHg
- Flash Point: 90.6±25.9 °C
- Vapor Pressure: 0.1±0.4 mmHg at 25°C
5-Chloro-2-(trifluoromethoxy)benzyl bromide Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
5-Chloro-2-(trifluoromethoxy)benzyl bromide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A013027702-250mg |
5-Chloro-2-(trifluoromethoxy)benzyl bromide |
1092461-19-2 | 97% | 250mg |
$484.80 | 2023-09-04 | |
| Alichem | A013027702-500mg |
5-Chloro-2-(trifluoromethoxy)benzyl bromide |
1092461-19-2 | 97% | 500mg |
$823.15 | 2023-09-04 | |
| Alichem | A013027702-1g |
5-Chloro-2-(trifluoromethoxy)benzyl bromide |
1092461-19-2 | 97% | 1g |
$1549.60 | 2023-09-04 | |
| TRC | C597345-50mg |
5-Chloro-2-(trifluoromethoxy)benzyl Bromide |
1092461-19-2 | 50mg |
$ 70.00 | 2022-06-06 | ||
| TRC | C597345-100mg |
5-Chloro-2-(trifluoromethoxy)benzyl Bromide |
1092461-19-2 | 100mg |
$ 95.00 | 2022-06-06 | ||
| TRC | C597345-500mg |
5-Chloro-2-(trifluoromethoxy)benzyl Bromide |
1092461-19-2 | 500mg |
$ 340.00 | 2022-06-06 | ||
| Apollo Scientific | PC302614-1g |
5-Chloro-2-(trifluoromethoxy)benzyl bromide |
1092461-19-2 | 98% | 1g |
￡122.00 | 2025-02-21 | |
| Apollo Scientific | PC302614-5g |
5-Chloro-2-(trifluoromethoxy)benzyl bromide |
1092461-19-2 | 98% | 5g |
￡510.00 | 2025-02-21 | |
| abcr | AB264457-1 g |
5-Chloro-2-(trifluoromethoxy)benzyl bromide, 97%; . |
1092461-19-2 | 97% | 1g |
€248.30 | 2023-06-22 | |
| abcr | AB264457-5 g |
5-Chloro-2-(trifluoromethoxy)benzyl bromide, 97%; . |
1092461-19-2 | 97% | 5g |
€865.90 | 2023-06-22 |
5-Chloro-2-(trifluoromethoxy)benzyl bromide Related Literature
-
Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
-
Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
-
Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
-
4. Excimer emission and magnetoluminescence of radical-based zinc(ii) complexes doped in host crystals?Shojiro Kimura,Tetsuro Kusamoto Chem. Commun., 2020,56, 11195-11198
-
Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
1092461-19-2 (5-Chloro-2-(trifluoromethoxy)benzyl bromide) Related Products
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- 1261606-06-7(4-Chloro-2-(trifluoromethoxy)benzyl bromide)
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