Cas no 107868-30-4 (Exemestane)

Exemestane structure
Exemestane structure
Product Name:Exemestane
CAS No:107868-30-4
MF:C20H24O2
MW:296.403366088867
CID:62700
PubChem ID:60198
Update Time:2025-09-27

Exemestane Chemical and Physical Properties

Names and Identifiers

    • 6-Methylene-androsta-1,4-diene-3,17-dione
    • 6-methylenandrosta-1,4-diene-3,17-dione
    • 6-METHYLENEANDROSTA-1,4-DIENE-3,17-DIONE
    • 10,13-dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-
    • EXEMESTANE
    • FCE-24304
    • AROMASIN
    • EXEMESTANCE
    • ExeMestane(AroMasin)
    • Anti-Estrogen AI Exemestaneknightlabs_leeisun
    • 6-methylenandrost-1,4-diene-3,17-dione
    • androsta-1,4-diene-6-methylene-3,17-dione
    • CE24304
    • EXALAMIDE
    • EXE
    • Exemestan
    • ExemestaneF
    • FCE 24304
    • PNU155971
    • ExeMestine
    • Exemestane D2
    • ExeMestane (USP)
    • Exemestanum
    • Exemestano
    • Exemestanum [INN-Latin]
    • Exemestano [INN-Spanish]
    • Exemestane [USAN:INN:BAN]
    • FCE24304
    • Aromasine
    • NY22HMQ4BX
    • 1,4-Androstadien-3,17-dione-6-Methylene-d2
    • (8R,9S,10R,13S,14S)-10,13-Dimethyl-6-methylene-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17(10H,14H)-dione
    • (8R,9S,10R,13S,14S)-10,13-diMethyl-6-Methylene-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione
    • ExeMestane SynonyMs 6-Methylenandrosta-1,4-diene-3,17-dione
    • Exemestane(FCE 24304)
    • BCPP000235
    • CAS-107868-30-4
    • AB00639936-09
    • BRD-K33425534-001-12-5
    • Exemestane, Aromasin
    • Curator_000009
    • PNU 155971
    • BCP23353
    • (1S,2R,10R,11S,15S)-2,15-dimethyl-8-methylidenetetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,14-dione
    • EXEMESTANE [USP MONOGRAPH]
    • C08162
    • Exemestane, United States Pharmacopeia (USP) Reference Standard
    • HY-13632
    • Aromasin (Pharmacia Upjohn)
    • MLS001424062
    • EXEMESTANE [MI]
    • NC00245
    • CHEMBL1200374
    • EXEMESTANE [USP-RS]
    • NCGC00271596-03
    • CCRIS 9351
    • CHEBI:4953
    • AKOS015895161
    • Exemestane for system suitability, European Pharmacopoeia (EP) Reference Standard
    • HMS3713H12
    • Aromasil
    • DTXSID5023037
    • C20H24O2
    • SR-01000759393
    • (8alpha,10alpha,13alpha)-6-Methylideneandrosta-1,4-Diene-3,17-Dione
    • Exemestane, >=98% (HPLC)
    • examestane
    • 6-Methylen-androst-1,4-diene-3,17-dione
    • AB00639936_11
    • Aromasin (TN)
    • Tox21_111499
    • EXEMESTANE [EP MONOGRAPH]
    • MFCD00866994
    • BFYIZQONLCFLEV-DAELLWKTSA-N
    • Exemestane, Pharmaceutical Secondary Standard; Certified Reference Material
    • Exemestanum (INN-Latin)
    • AKOS015840113
    • PNU-155971
    • CCG-100995
    • MLS000759419
    • Androsta-1,4-diene-3,17-dione, 6-methylene-; 6-Methyleneandrosta-1,4-diene-3,17-dione; Aromasil; Aromasin; Exemestane; FCE 24304
    • HY-13632R
    • AB00639936-06
    • KS-5136
    • HSDB 7463
    • DTXCID003037
    • A801772
    • EXEMESTANE [ORANGE BOOK]
    • SR-01000759393-4
    • EXEMESTANE (MART.)
    • AS-31053
    • E0941
    • NSC-713563
    • Exemestane, European Pharmacopoeia (EP) Reference Standard
    • CPD000466314
    • Tox21_111499_1
    • NS00000304
    • HMS2051J04
    • BCP9000676
    • EXEMESTANE [HSDB]
    • Androsta-1,4-diene-3,17-dione, 6-methylene-
    • Q418819
    • AC-2171
    • (8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione
    • UNII-NY22HMQ4BX
    • NCGC00095289-01
    • Exemestane (JAN/USP/INN)
    • NSC 758907
    • 6-methylideneandrosta-1,4-diene-3,17-dione
    • CS-0694867
    • D00963
    • GTPL7073
    • BDBM50398447
    • AB00639936-10
    • EXEMESTANE [USAN]
    • EXEMESTANE (EP MONOGRAPH)
    • EXEMESTANE [MART.]
    • SCHEMBL6215
    • Exemestane; aromasin
    • Exemestane [INN]
    • CS-1766
    • 6-Methylenandrosta-1,17-dione
    • EXM
    • EXEMESTANE [JAN]
    • 6-methylenandrost-1,4-dien-3,17-dione
    • AB00639936-08
    • EXEMESTANE [VANDF]
    • s1196
    • DB00990
    • EXEMESTANE [WHO-DD]
    • NSC-758907
    • EXEMESTANE (USP MONOGRAPH)
    • EXEMESTANE (USP-RS)
    • Exemestane (Standard)
    • Nikidess
    • SMR000466314
    • NSC713563
    • BCP0726000226
    • L02BG06
    • Exemestano (INN-Spanish)
    • 107868-30-4
    • Exemestane(FCE 24304)?
    • Exemestane
    • MDL： MFCD00866994
    • Inchi： 1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
    • InChI Key： BFYIZQONLCFLEV-DAELLWKTSA-N
    • SMILES： O=C1CC[C@@H]2[C@]1(C)CC[C@@H]1[C@]3(C=CC(C=C3C(=C)C[C@@H]21)=O)C

Computed Properties

  • Exact Mass: 296.17800
  • Monoisotopic Mass: 296.17763
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 22
  • Rotatable Bond Count: 0
  • Complexity: 653
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 5
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 2
  • XLogP3: 3.1
  • Topological Polar Surface Area: 34.1

Experimental Properties

  • Color/Form: Powder
  • Density: 1.1±0.1 g/cm3
  • Melting Point: 155.13 oC
  • Boiling Point: 453.7°C at 760 mmHg
  • Flash Point: 169.0±25.7 °C
  • Refractive Index: 1.572
  • Solubility: DMSO: ≥20mg/mL
  • PSA: 34.14000
  • LogP: 4.02950
  • Solubility: Soluble in methanol, insoluble in water
  • Specific Rotation: +250° - +300° (c=1, MeOH)
  • Vapor Pressure: 0.0±1.1 mmHg at 25°C

Exemestane Security Information

  • Signal Word：Danger
  • Hazard Statement： H360; H411
  • Warning Statement： P201; P202; P273; P281; P308+P313; P391; P405; P501
  • Hazardous Material transportation number：UN 3261 8/PG 2
  • WGK Germany：3
  • Hazard Category Code： 60-61-51
  • Safety Instruction： S26-S36/37/39
  • Hazardous Material Identification： C
  • Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
  • Safety Term：8
  • Packing Group：III
  • Risk Phrases：R36/37/38
  • Packing Group：III
  • Hazard Level：8

Exemestane Customs Data

  • HS CODE：2937900090
  • Customs Data：

    China Customs Code:

    2937900090

    Overview:

    HS: 2937900090 Other hormones and their derivatives and structural analogues Tax refund rate:9.0% Regulatory conditions:Q(Customs clearance form for imported drugs) VAT:17.0% MFN tariff:4.0% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Regulatory conditions:

    Q.Customs clearance form for imported drugs

    Summary:

    HS: 2937900090 Tax rebate rate:9.0% Supervision conditions:q(report of inspection of soundness on import medicines) VAT:17.0% MFN tariff:4.0% General tariff:30.0%

Exemestane Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
E829828-5g
Exemestane
 107868-30-4 98%
5g
 ￥1,299.00 2022-10-10
TRC
E957000-5mg
Exemestane
 107868-30-4
5mg
 $ 69.00 2023-09-07
TRC
E957000-10mg
Exemestane
 107868-30-4
10mg
 $ 85.00 2023-09-07
TRC
E957000-25mg
Exemestane
 107868-30-4
25mg
 $ 132.00 2023-09-07
TRC
E957000-50mg
Exemestane
 107868-30-4
50mg
 $148.00 2023-05-18
TRC
E957000-100mg
Exemestane
 107868-30-4
100mg
 $170.00 2023-05-18
TRC
E957000-500mg
Exemestane
 107868-30-4
500mg
 $242.00 2023-05-18
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
E64100-1g
Exemestane
 107868-30-4 98%
1g
 ￥308.0 2023-09-07
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
E64100-200mg
Exemestane
 107868-30-4 98%
200mg
 ￥88.0 2021-09-09
SHANG HAI TAO SHU Biotechnology Co., Ltd.
T1587-5 mg
Exemestane
 107868-30-4 99.35%
5mg
 ￥271.00 2022-02-28

Exemestane Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Hydrochloric acid Solvents: Water ;  24 h, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  neutralized, rt
Reference
Derivatives of exemestane-synthesis and evaluation of aromatase inhibition
Goerlitzer, K.; et al, Pharmazie, 2006, 61(7), 575-581

Production Method 2

Reaction Conditions
1.1 Reagents: Pyrrolidine ;  20 h, reflux
1.2 Solvents: Ethanol ,  Benzene ,  Water ;  5 h, rt
2.1 Reagents: Hydrochloric acid Solvents: Water ;  24 h, rt
2.2 Reagents: Sodium bicarbonate Solvents: Water ;  neutralized, rt
Reference
Derivatives of exemestane-synthesis and evaluation of aromatase inhibition
Goerlitzer, K.; et al, Pharmazie, 2006, 61(7), 575-581

Exemestane Raw materials

Exemestane Preparation Products

Exemestane Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:107868-30-4)Exemestane
Order Number:A801772
Stock Status:in Stock
Quantity:50mg/100mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:38
Price ($):159.0/251.0
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:107868-30-4)Exemestane
Order Number:sfd12833
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally
Hunan Well Medicine Synthesis Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
(CAS:107868-30-4)Exemestane
Order Number:25
Stock Status:in Stock
Quantity:KG
Purity:99%
Pricing Information Last Updated:Wednesday, 31 December 2025 09:08
Price ($):inquiry
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:107868-30-4)依西美坦
Order Number:LE8484154
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:47
Price ($):discuss personally

Exemestane Related Literature

Related Categories

107868-30-4 (Exemestane) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:107868-30-4)Exemestane
A801772
Purity:99%/99%
Quantity:50mg/100mg
Price ($):159.0/251.0
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:107868-30-4)Exemestane
sfd12833
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email