Production Method 1

106877-42-3

151-10-0

84370-87-6

Reaction Conditions

1.1 Reagents: 4,4′-Difluoro-1,1′-biphenyl ,  Cuprous chloride Solvents: Acetonitrile ;  30 min, 0 °C
2.1 Reagents: Sodium nitrite ,  Hydrofluoric acid Solvents: Dimethylformamide ,  Acetonitrile ,  Water ;  0 °C; 10 min, 0 °C; 5 min, 0 °C

Reference

Trifluoromethylation of arenediazonium salts with fluoroform-derived CuCF3 in aqueous media

Lishchynskyi, Anton; et al, Chemical Communications (Cambridge, 2014, 50(71), 10237-10240

Production Method 2

2735-04-8

77152-08-0

106877-42-3

151-10-0

84370-87-6

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrofluoric acid Solvents: Dimethylformamide ,  Acetonitrile ,  Water ;  0 °C; 10 min, 0 °C; 5 min, 0 °C

Reference

Trifluoromethylation of arenediazonium salts with fluoroform-derived CuCF3 in aqueous media

Lishchynskyi, Anton; et al, Chemical Communications (Cambridge, 2014, 50(71), 10237-10240

Benzene, 2,4-dimethoxy-1-(trifluoromethyl)- Raw materials

• 2,4-Dimethoxyaniline
• Copper, (trifluoromethyl)-

Benzene, 2,4-dimethoxy-1-(trifluoromethyl)- Preparation Products

• Benzene, 2,4-dimethoxy-1-(trifluoromethyl)- (106877-42-3)
• 1,3-Dimethoxybenzene (151-10-0)
• 1-isocyanato-2,4-dimethoxybenzene (84370-87-6)

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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Trifluoromethylbenzenes

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