Cas no 1060812-07-8 (2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine)

2-(2-Chloropyridin-4-yl)-2-methylpropan-1-amine is a versatile chloropyridine derivative with a branched alkylamine substituent, offering a unique structural motif for synthetic applications. Its reactive chloropyridine core enables selective functionalization, while the sterically hindered amine group enhances stability and facilitates further derivatization. This compound is particularly valuable in pharmaceutical and agrochemical research as a key intermediate for the development of biologically active molecules. The presence of both electron-withdrawing (chloro) and electron-donating (amine) groups provides tunable reactivity, making it suitable for cross-coupling reactions, nucleophilic substitutions, and heterocyclic synthesis. Its well-defined purity and consistent performance ensure reliability in complex synthetic pathways.
2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine structure
1060812-07-8 structure
Product Name:2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine
CAS No:1060812-07-8
MF:C9H13ClN2
MW:184.665920972824
MDL:MFCD13188905
CID:2853304
PubChem ID:57526894
Update Time:2025-05-22

2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine Chemical and Physical Properties

Names and Identifiers

    • 2-(2-CHLOROPYRIDIN-4-YL)-2-METHYLPROPAN-1-AMINE
    • AB67361
    • 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine
    • MDL: MFCD13188905
    • Inchi: 1S/C9H13ClN2/c1-9(2,6-11)7-3-4-12-8(10)5-7/h3-5H,6,11H2,1-2H3
    • InChI Key: WSVXEJSJBRVXTL-UHFFFAOYSA-N
    • SMILES: ClC1C=C(C=CN=1)C(C)(C)CN

Computed Properties

  • Exact Mass: 184.0767261g/mol
  • Monoisotopic Mass: 184.0767261g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 148
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2
  • Topological Polar Surface Area: 38.9

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Additional information on 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine

Comprehensive Overview of 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine (CAS No. 1060812-07-8)

The compound 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine (CAS No. 1060812-07-8) is a specialized organic molecule that has garnered significant attention in pharmaceutical and agrochemical research. Its unique structural features, including the chloropyridine moiety and the methylpropan-1-amine group, make it a versatile intermediate for synthesizing more complex molecules. Researchers and industry professionals frequently search for this compound due to its potential applications in drug discovery and crop protection formulations.

One of the most searched questions related to 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine is its solubility and stability under various conditions. Studies indicate that this compound exhibits moderate solubility in polar organic solvents like dimethyl sulfoxide (DMSO) and methanol, which is critical for its handling in laboratory settings. Additionally, its stability at room temperature makes it a reliable candidate for long-term storage, a feature highly valued by chemists and formulators.

In the context of current trends, the demand for chloropyridine derivatives has surged due to their role in developing next-generation pharmaceuticals. For instance, 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine is often explored as a building block for kinase inhibitors, a class of drugs targeting cancer and inflammatory diseases. This aligns with the growing interest in personalized medicine and targeted therapies, which dominate today's biomedical research landscape.

Another hot topic is the compound's potential in agrochemical innovation. With the global push toward sustainable farming, researchers are investigating 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine as a precursor for eco-friendly pesticides. Its structural adaptability allows for modifications that enhance efficacy while minimizing environmental impact, addressing the urgent need for greener alternatives in agriculture.

From a synthetic chemistry perspective, the amine functional group in 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine offers reactive sites for further derivatization. This property is particularly valuable in high-throughput screening and combinatorial chemistry, where rapid diversification of molecular libraries is essential. Such applications are frequently discussed in forums and publications focused on drug discovery acceleration.

Safety and handling protocols for 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine are also a common query among laboratory personnel. While the compound is not classified as hazardous under standard regulations, proper personal protective equipment (PPE) such as gloves and goggles is recommended during manipulation. This emphasis on safety reflects the broader industry shift toward responsible chemical management.

In summary, 2-(2-Chloropyridin-4-YL)-2-methylpropan-1-amine (CAS No. 1060812-07-8) is a multifaceted compound with promising applications in both pharmaceuticals and agrochemicals. Its relevance to cutting-edge research areas like targeted therapy and sustainable agriculture ensures its continued prominence in scientific discourse. As innovation progresses, this compound is poised to play a pivotal role in addressing some of the most pressing challenges in modern science.

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