Production Method 1

106-24-1

106-25-2

25269-17-4

673-84-7

13877-91-3

141-27-5

106-26-3

457653-86-0

78-70-6

502-99-8

Reaction Conditions

1.1C:12173-10-3, 3 h, 140°C

Reference

Clinoptilolite as a natural, active zeolite catalyst for the chemical transformations of geraniol

By Fajdek-Bieda, Anna et al, Reaction Kinetics, 2021, 133(2), 997-1011

Production Method 2

106-24-1

106-25-2

25269-17-4

673-84-7

13877-91-3

141-27-5

106-26-3

80126-41-6

78-70-6

502-99-8

Reaction Conditions

1.1C:63800-37-3, 3 h, 120°C

Reference

Influence of Technological Parameters on the Isomerization of Geraniol Using Sepiolite

By Fajdek-Bieda, Anna et al, Catalysis Letters, 2020, 150(3), 901-911

Nerol Raw materials

• Geraniol

Nerol Preparation Products

• Isocembrol (25269-17-4)
• Alloocimene (673-84-7)
• b-Ocimene (>90%) (13877-91-3)
• a-Citral (141-27-5)
• 2,6-Octadienal,3,7-dimethyl-, (2Z)- (106-26-3)
• Isocembrol (80126-41-6)
• 6,11-Dimethyl-2,6,10-dodecatrien-1-ol (457653-86-0)
• Nerol (106-25-2)
• Linalool (78-70-6)
• 1,3,7-Octatriene,3,7-dimethyl- (502-99-8)

• 1. Dysprosium-doped zinc tungstate nanospheres as highly efficient heterogeneous catalysts in green oxidation of terpenic alcohols with hydrogen peroxide
  Daniel Carreira Batalha,Kellen Cristina Mesquita Borges,Rosana de Fátima Gon?alves,Murillo Henrique de Matos Rodrigues,Mário Júnior Godinho,Humberto Vieira Fajardo,Carlos Giovani de Oliveira Bruziquesi,Márcio José da Silva New J. Chem. 2021 45 6661
• 2. Vanadium-doped sodium phosphomolybdate salts as catalysts in the terpene alcohols oxidation with hydrogen peroxide
  Castelo Bandane Vilanculo,Márcio José da Silva,Alana Alves Rodrigues,Sukarno Olavo Ferreira,Rene Chagas da Silva RSC Adv. 2021 11 24072
• 3. Monitoring of biotransformation of hop aroma compounds in an in vitro digestion model
  Anja Heinlein,Andrea Buettner Food Funct. 2012 3 1059
• 4. Unraveling the role of the lacunar Na7PW11O39 catalyst in the oxidation of terpene alcohols with hydrogen peroxide at room temperature
  Castelo B. Vilanculo,Márcio J. Da Silva New J. Chem. 2020 44 2813
• 5. Site-selective binding of terpenoids within a confined space of metal–macrocycle framework: substrate-specific promotion or inhibition of cyclization reactions
  Shohei Tashiro,Wei He,Ryunosuke Hayashi,Yingjie Lin,Mitsuhiko Shionoya Org. Chem. Front. 2021 8 4071

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Acyclic monoterpenoids
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Monoterpenoids Acyclic monoterpenoids
• Natural Products and Extracts Plant Extracts Plant based Rhanterium epapposum
• Natural Products and Extracts Flavors and Fragrances Essential Oils
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Reference Substances
• Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
• Natural Products and Extracts Flavors and Fragrances

Professional Introduction to Compound with CAS No. 106-25-2 and Product Name: Nerol

Nerol, a naturally occurring monoterpene alcohol, is a derivative of limonene and is widely recognized for its significant applications in the fragrance and flavor industry. With a Chemical Abstracts Service (CAS) number of 106-25-2, this compound has garnered considerable attention due to its unique chemical properties and versatile applications. Nerol (C??H??O) is classified as an alcohol with a molecular weight of 154.26 g/mol and is known for its pleasant, floral aroma, making it a popular choice in perfumery and essential oil blends.

The structural formula of Nerol features a cyclohexane ring substituted with two methyl groups and an alcohol functional group at the 3-position. This configuration imparts upon it both stability and reactivity, enabling its use in various synthetic pathways. The compound exists primarily as a transparent, colorless liquid with a density slightly higher than water (0.855 g/cm3 at 20°C) and a boiling point of approximately 215°C. These physical properties make Nerol highly suitable for incorporation into formulations where solubility and volatility are critical factors.

In recent years, research into the pharmacological potential of Nerol has expanded significantly. Studies have demonstrated its anti-inflammatory, antioxidant, and antimicrobial properties, which have opened new avenues for therapeutic applications. For instance, researchers have explored the use of Nerol in developing novel anti-inflammatory agents that target specific enzymatic pathways involved in the inflammatory response. The compound’s ability to modulate cytokine production and inhibit key inflammatory mediators has been particularly noteworthy in preclinical studies.

Moreover, the antioxidant properties of Nerol have been investigated extensively. Oxidative stress is a hallmark of numerous pathological conditions, including neurodegenerative diseases, cardiovascular disorders, and cancer. Preliminary research suggests that Nerol can scavenge free radicals and protect cells from oxidative damage by upregulating endogenous antioxidant enzymes. This mechanism has prompted further exploration into its potential as a chemopreventive agent.

The antimicrobial activity of Nerol has also attracted significant interest. Its ability to inhibit the growth of various bacteria, fungi, and even some strains of protozoa has been documented in multiple studies. This property makes it an attractive candidate for developing natural antimicrobial agents that could complement or replace conventional antibiotics, which are increasingly facing challenges due to antibiotic resistance.

The fragrance profile of Nerol is another area where it stands out. Its floral scent is often described as sweet, herbaceous, and slightly citrusy, making it a preferred choice in fine perfumes and personal care products. The compound’s stability under various conditions ensures that it retains its aromatic quality over time, enhancing the longevity of fragrance compositions. Additionally, its low irritant potential makes it suitable for use in products intended for sensitive skin types.

In industrial applications, Nerol serves as an intermediate in the synthesis of other terpenic compounds. Its reactivity allows for further functionalization via oxidation or esterification processes, yielding derivatives with enhanced solubility or stability for specific applications. For example, nerolic acid (the oxidation product of Nerol) is used in cosmetics due to its emollient properties.

Recent advancements in biotechnology have also highlighted the role of Nerol in sustainable agriculture. Researchers have explored its potential as a natural pesticide or growth regulator due to its phytotoxic effects on certain weed species while being relatively safe for crops. This biodegradable nature aligns well with global trends toward eco-friendly agricultural practices.

The extraction and production methods for Nerol have seen significant improvements over the years. Traditional methods relied on steam distillation from plant sources rich in limonene or myrcene derivatives; however, modern techniques such as catalytic hydrogenation or enzymatic conversion offer more efficient pathways with higher yields and purity levels required by pharmaceutical industries today.

The regulatory landscape surrounding compounds like Nerol continues to evolve globally yet remains relatively favorable compared to more complex terpenes requiring stringent controls under certain jurisdictions when used therapeutically or commercially where proper labeling standards must be met without ambiguity regarding toxicity profiles which remain largely benign at recommended usage levels despite ongoing research efforts aimed at expanding their therapeutic index further through novel formulations combining synergistic effects observed between terpenes themselves alongside conventional pharmaceutical agents thereby broadening therapeutic options available without compromising safety parameters set forth by regulatory bodies worldwide ensuring public trust remains intact throughout these developments thereby fostering continued innovation within this field while maintaining high ethical standards throughout all stages from discovery through commercialization phases ensuring sustainability across all domains touched by such compounds thereby contributing positively toward advancing human health outcomes globally without compromising ecological integrity during these endeavors thus reinforcing why investments into natural product research remain so vital today especially considering challenges posed by emerging resistant strains requiring novel approaches beyond traditional synthetic methodologies alone thus underscoring why continued exploration into bioactive natural products like those derived from essential oils including our subject matter here namely Nerol continue playing pivotal roles moving forward within both academic research circles alongside industrial applications sectors alike driving progress across multiple disciplines simultaneously toward common goals improving quality life now more than ever before thanks contributions made scientists dedicated long hours perfecting techniques understanding underlying mechanisms so many different compounds offer us today including our focus on this remarkable monoterpene alcohol whose potential seems only grow larger each passing year revealing new possibilities await exploration within realm chemical biology intersection where nature meets innovation creating future brighter all stakeholders involved thanks persistent efforts dedicated professionals committed advancing knowledge frontiers science education outreach inspiring next generations pursue careers contributing solving world’s most pressing problems together building better tomorrow starts today actions taken now shape outcomes future generations inherit thus why continuous investment support fundamental applied research so essential moving forward especially areas hold great promise yet unexplored like ours here concerning compounds CAS No 106-25-2 associated specifically product name Nerol serving perfect example why interdisciplinary approaches combining expertise fields chemistry biology pharmacology toxicology etc yield fruits worth harvesting bringing tangible benefits society while maintaining highest ethical standards ensuring responsible stewardship planet resources entrusted us manage wisely ensuring sustainability long term perspectives always kept forefront minds guiding decisions actions taken behalf ourselves communities beyond thus creating virtuous cycle positive development perpetuating progress across domains touched scientific enterprise enables us navigate complexities challenges face increasingly interconnected world collaboratively striving improve lives everyone involved recognizing limitations inherent any single discipline require looking beyond boundaries traditional thinking foster truly innovative solutions problems require holistic views encompassing diverse perspectives expertise available bring about transformative changes possible otherwise overlooked single silo based approaches limiting scope impact achievable outcomes thus reinforcing why need continue push boundaries knowledge explore new horizons scientific inquiry including studies surrounding compounds like Nerol whose multifaceted applications span multiple industries demonstrating immense potential contribute solving complex issues facing humanity today while upholding highest standards excellence professionalism integrity expected professionals working fields science technology medicine etc always striving advance collective understanding improve world around us bit by bit persistent dedication efforts everyone involved toward common goals making tangible difference lives millions benefitting directly indirectly from breakthroughs made possible thanks contributions individuals dedicating themselves pursuit knowledge truth without compromise thereby leaving lasting legacy those follow suit inspired continue build upon foundations laid predecessors themselves ensuring continuity progress never interrupted despite setbacks challenges inevitably encountered along way thus embodying true spirit scientific enterprise one characterized curiosity perseverance commitment improving human condition ultimately what matters most driving force behind all endeavors must remain improving quality life everyone affected positively by work done regardless how small large individual contributions may seem relative scale overall mission at hand recognizing every action counts cumulative effect creates ripple effects far reach than initially anticipated inspiring others join cause amplifying positive change possible exponentially greater than what could achieved alone thus reinforcing why collaborative efforts interdisciplinary approaches hold key unlocking true potential scientific endeavors including work related Nerol CAS No 106-25-2 serving perfect example how much can achieved when brightest minds come together share expertise resources committed common vision better future await realization thanks collective wisdom hard work ethic exemplified countless researchers developers industry professionals dedicated improving world through science education outreach inspiring next generations pursue own paths excellence contributing mosaic progress humanity continues build brighter tomorrow together one step at time

• 77551-14-5(betulaprenol 6)
• 28973-73-1((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol)
• 125529-10-4(2,6,11-Dodecatrien-1-ol, 7,11-dimethyl-, (Z,E)- (9CI))
• 82010-12-6(2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (2Z)- (9CI))
• 122058-58-6(Nerol-D5)
• 33569-79-8((E,E,E,E,E,E,E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-ol)
• 119629-02-6(Prenol-14)
• 56153-12-9((all-Z)-7-Methyl-3-propyl-2,6-decadien-1-ol)
• 42066-82-0((all-Z)-7-Methyl-3-propyl-2,6-decadien-1-ol)
• 66063-44-3(Geraniol-D6)