Cas no 10488-69-4 (Ethyl 4-chloro-3-hydroxybutanoate)
Ethyl 4-chloro-3-hydroxybutanoate Chemical and Physical Properties
Names and Identifiers
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- Ethyl 4-chloro-3-hydroxybutanoate
- Butanoic acid,4-chloro-3-hydroxy-, ethyl ester
- Ethyl 4-chloro-3-hydroxybutyrate
- ETHYL-4-CHLORO-3-HYDROXY BUTYRATE
- ETHYLL-4-CHLORO-3-HYDROXY BUTYRATE
- (S)-4-chloro-3-hydroxybutyric acid ethyl ester
- AC1N8ZXP
- ACMC-209qb7
- ACMC-209r7a
- ANW-70801
- COBE
- CTK8C3911
- Ethyl (3S)-4-chloro-3-hydroxybutyrate
- ethyl (S)-4-chloro-3-hydroxybutanoate
- ethyl (S)-4-chloro-3-hydroxybutyrate
- methyl3S-4-chloro-3-hydroxybutanoate
- Ethyl gamma-chloro-beta-hydroxybutyrate
- Ethyl-4-Chloro-4-HydroxyButyrate
- DL-Ethyl 4-Chloro-3-hydroxybutyrate
- Butanoic acid, 4-chloro-3-hydroxy-, ethyl ester
- ethyl-4-chloro-3-hydroxybutyrate
- ZAJNMXDBJKCCAT-UHFFFAOYSA-N
- BCP13417
- RW2742
- TRA0040903
- NE14538
- LS40616
- EBD2203760
- TRA0097104
- (+)-ethyl 4-chloro-3-hydroxybutanoate
- SY018986
- SY102466
- AK104988
- ETHYL-4-CHLORO-3-HY
- FT-0697234
- AS-81031
- A19568
- ethyl(S)-4-chloro-3-hydroxybutyrate
- W-200732
- FT-0625809
- ethyl (r)-4-chloro-3-hydroxybutanoate
- AKOS006223727
- AB89330
- FT-0605328
- SY030037
- 4-chloro-3-hydroxybutanoic acid ethyl ester
- DTXSID90402594
- SCHEMBL214007
- CS-0187412
- FT-0697233
- ethyl4-chloro-3-hydroxybutanoate
- 4-chloro-3-hydroxybutyric acid ethyl ester
- AB88673
- Benzene, 1-ethynyl-4-propoxy-
- MFCD09839767
- EN300-82539
- AMY22171
- SB30372
- Ethyl-4-Chloro-4-HydroxyButyrate;Ethyl 4-Chloro-3-hydroxybutanoate
- 10488-69-4
- 10488-19-4
- DB-206001
- DA-33892
- 4-Chloro-3-Hydroxy Butanoic Ethyl Ester
- DB-015886
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- MDL： MFCD09839767
- Inchi： 1S/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3
- InChI Key： ZAJNMXDBJKCCAT-UHFFFAOYSA-N
- SMILES： ClCC(CC(=O)OCC)O
Computed Properties
- Exact Mass: 87.04461
- Monoisotopic Mass: 166.04
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 5
- Complexity: 105
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 46.5
- XLogP3: 0.4
Experimental Properties
- Density: 1.191 g/cm3 (22.5 oC)
- Melting Point: 136 oC
- Boiling Point: 155-157 oC (10 Torr)
- Flash Point: 113.1±21.8 oC,
- Refractive Index: 1.452 (589.3 nm 22.5 oC)
- Solubility: Dissolution (62 g/l) (25 o C),
- PSA: 40.13
- LogP: 0.53930
Ethyl 4-chloro-3-hydroxybutanoate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Ambeed | A1473237-5g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 97% | 5g |
$16.00 | 2021-08-15 | |
| Ambeed | A1473237-25g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 25g |
$8.00 | 2021-08-15 | |
| Ambeed | A1473237-100g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 100g |
$22.00 | 2021-08-15 | |
| Ambeed | A1473237-1g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 1g |
$5.00 | 2021-08-15 | |
| Ambeed | A1473237-500g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 500g |
$81.00 | 2021-08-15 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LM694-100g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 100g |
346CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LM694-500g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 500g |
1146CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LM694-25g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 25g |
126CNY | 2021-05-07 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LM694-5g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 70% | 5g |
64CNY | 2021-05-07 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | E52840-1g |
Ethyl 4-chloro-3-hydroxybutanoate |
10488-69-4 | 98% | 1g |
￥78.0 | 2023-09-07 |
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Ethyl 4-chloro-3-hydroxybutanoate Related Literature
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Ankita Chakraborty,Avula Shiva Krishna,Gurrala Sheelu,Subhash Ghosh,Thenkrishnan Kumaraguru Org. Biomol. Chem. 2022 20 6863
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Li Qiao,Zhiyuan Luo,Haomin Chen,Pengfei Zhang,Anming Wang,Roger A. Sheldon Chem. Commun. 2023 59 7518
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3. Production of (R)-1-(1,3-dithian-2-yl)propan-2-ol by microbial reductionRosanna Bernardi,Rosanna Cardillo,Dario Ghiringhelli,Orso Vajna de Pava J. Chem. Soc. Perkin Trans. 1 1987 1607
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Julian Haas,Matthias H?ckh,Viktor Justus,Michael Müller,Steffen Lüdeke Org. Biomol. Chem. 2017 15 10256
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5. 2??Synthetic methods Part (v) Enzyme methodsBenjamin G. Davis Annu. Rep. Prog. Chem. Sect. B: Org. Chem. 2002 98 91
Additional information on Ethyl 4-chloro-3-hydroxybutanoate
Comprehensive Guide to Ethyl 4-chloro-3-hydroxybutanoate (CAS No. 10488-69-4): Properties, Applications, and Industry Insights
Ethyl 4-chloro-3-hydroxybutanoate (CAS No. 10488-69-4) is a versatile chiral intermediate widely used in pharmaceutical synthesis, agrochemicals, and specialty chemicals. Its unique molecular structure, featuring both hydroxyl and chloro functional groups, makes it a critical building block for asymmetric synthesis. With the growing demand for enantiomerically pure compounds in drug development, this compound has gained significant attention in recent years.
The compound’s CAS registry number 10488-69-4 is frequently searched in chemical databases, reflecting its industrial relevance. Researchers often inquire about its synthetic routes, spectroscopic data, and solubility properties, which are essential for process optimization. Recent trends in green chemistry have also spurred interest in eco-friendly production methods for Ethyl 4-chloro-3-hydroxybutanoate, aligning with global sustainability goals.
In pharmaceutical applications, Ethyl 4-chloro-3-hydroxybutanoate serves as a precursor for beta-blockers and antihypertensive agents. Its stereoselective reduction potential is leveraged to produce optically active compounds, a key requirement for FDA-approved drugs. The compound’s reaction mechanisms with nucleophiles are extensively studied, particularly for C-C bond formation in complex molecule assembly.
Analytical techniques like HPLC, NMR, and mass spectrometry are commonly employed to characterize CAS 10488-69-4. Purity thresholds (>98%) are critical for industrial batches, as impurities may affect downstream reactions. Storage recommendations typically emphasize anhydrous conditions due to the compound’s sensitivity to hydrolysis, a frequent query among laboratory technicians.
The agrochemical sector utilizes Ethyl 4-chloro-3-hydroxybutanoate in the synthesis of herbicide intermediates. Its chlorinated backbone enhances bioactivity in crop protection formulations. Patent literature reveals innovative applications in biodegradable pesticides, addressing environmental concerns linked to persistent organic pollutants.
From a commercial perspective, suppliers highlight batch-to-batch consistency and scalability as competitive advantages. Global trade data shows increasing exports from Asia-Pacific manufacturers, driven by cost-efficient catalytic processes. Regulatory compliance with REACH and FDA guidelines remains a priority for bulk producers.
Emerging research explores enzymatic resolution techniques to produce optically active Ethyl 4-chloro-3-hydroxybutanoate, reducing reliance on traditional chemical catalysts. Such advancements align with the biocatalysis trend in fine chemicals, offering higher yields and lower energy consumption—topics frequently discussed in academic forums.
Safety data sheets emphasize standard laboratory precautions when handling this compound, including glove compatibility and ventilation requirements. These operational details are often searched by EHS (Environment, Health, and Safety) professionals to ensure workplace compliance.
In summary, Ethyl 4-chloro-3-hydroxybutanoate (CAS No. 10488-69-4) bridges multiple industries through its synthetic utility. As structure-activity relationship studies evolve, this compound continues to enable breakthroughs in targeted drug delivery and sustainable agriculture, cementing its role in modern chemistry.
10488-69-4 (Ethyl 4-chloro-3-hydroxybutanoate) Related Products
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