Cas no 1033203-56-3 (4-methoxy-2-nitro-Pyridine)

4-Methoxy-2-nitropyridine is a nitro-substituted pyridine derivative featuring a methoxy group at the 4-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. The electron-withdrawing nitro group and electron-donating methoxy group create a reactive scaffold suitable for further functionalization, including nucleophilic aromatic substitution and reduction reactions. Its well-defined structure and stability under controlled conditions make it a valuable building block for heterocyclic chemistry. The compound is typically handled under standard laboratory conditions, with appropriate precautions due to its nitro-containing moiety. Its purity and consistent performance are critical for reproducible synthetic outcomes.
4-methoxy-2-nitro-Pyridine structure
4-methoxy-2-nitro-Pyridine structure
Product Name:4-methoxy-2-nitro-Pyridine
CAS No:1033203-56-3
MF:C6H6N2O3
MW:154.12344121933
MDL:MFCD11100683
CID:1096906
PubChem ID:55264974
Update Time:2025-10-29

4-methoxy-2-nitro-Pyridine Chemical and Physical Properties

Names and Identifiers

    • 4-methoxy-2-nitro-Pyridine
    • MFCD11100683
    • 1033203-56-3
    • SCHEMBL17222805
    • 4-methoxy-2-nitropyridine
    • SY289330
    • AKOS006307899
    • MDL: MFCD11100683
    • Inchi: 1S/C6H6N2O3/c1-11-5-2-3-7-6(4-5)8(9)10/h2-4H,1H3
    • InChI Key: CKYYIROFNBIZAU-UHFFFAOYSA-N
    • SMILES: O(C)C1C=CN=C(C=1)[N+](=O)[O-]

Computed Properties

  • Exact Mass: 154.037842g/mol
  • Monoisotopic Mass: 154.037842g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 145
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 154.12g/mol
  • XLogP3: 0.7
  • Topological Polar Surface Area: 67.9?2

4-methoxy-2-nitro-Pyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
eNovation Chemicals LLC
Y1198013-1g
4-Methoxy-2-nitropyridine
1033203-56-3 95%
1g
$935 2024-07-19
eNovation Chemicals LLC
Y1198013-1g
4-Methoxy-2-nitropyridine
1033203-56-3 95%
1g
$935 2025-03-01
eNovation Chemicals LLC
Y1198013-1g
4-Methoxy-2-nitropyridine
1033203-56-3 95%
1g
$935 2025-02-21

Additional information on 4-methoxy-2-nitro-Pyridine

Recent Advances in the Study of 1033203-56-3 and 4-methoxy-2-nitro-Pyridine in Chemical Biology and Pharmaceutical Research

The chemical compound 1033203-56-3, along with its derivative 4-methoxy-2-nitro-Pyridine, has garnered significant attention in recent years due to its potential applications in chemical biology and pharmaceutical research. These compounds are particularly notable for their role in the development of novel therapeutic agents and as intermediates in organic synthesis. This research brief aims to provide an up-to-date overview of the latest findings related to these compounds, focusing on their synthesis, biological activity, and potential industrial applications.

Recent studies have highlighted the versatility of 1033203-56-3 as a building block in medicinal chemistry. Its structural features make it a valuable precursor for the synthesis of various heterocyclic compounds, which are often employed in drug discovery. Specifically, 4-methoxy-2-nitro-Pyridine, a derivative of 1033203-56-3, has been investigated for its unique electronic properties and reactivity, which are crucial for designing targeted molecular probes and inhibitors.

One of the key breakthroughs in this area involves the use of 4-methoxy-2-nitro-Pyridine in the development of enzyme inhibitors. Researchers have demonstrated that this compound can effectively modulate the activity of certain kinases and proteases, making it a promising candidate for treating diseases such as cancer and inflammatory disorders. The nitro group in the pyridine ring plays a pivotal role in these interactions, facilitating the formation of stable enzyme-inhibitor complexes.

In addition to its biological applications, 1033203-56-3 has also been explored for its potential in material science. Recent reports indicate that this compound can serve as a ligand in coordination chemistry, enabling the synthesis of metal-organic frameworks (MOFs) with unique catalytic properties. These MOFs have shown promise in applications such as gas storage, separation, and heterogeneous catalysis, further expanding the utility of 1033203-56-3 beyond traditional pharmaceutical contexts.

The synthesis of 4-methoxy-2-nitro-Pyridine has also seen significant advancements. Novel methodologies involving palladium-catalyzed cross-coupling reactions have been developed to improve the yield and selectivity of this compound. These synthetic routes not only enhance the efficiency of production but also reduce the environmental impact by minimizing the use of hazardous reagents. Such innovations are critical for scaling up the industrial production of 4-methoxy-2-nitro-Pyridine while adhering to green chemistry principles.

Despite these promising developments, challenges remain in the widespread adoption of 1033203-56-3 and its derivatives. Issues such as solubility, stability, and bioavailability need to be addressed to fully realize their therapeutic potential. Ongoing research is focused on structural modifications and formulation strategies to overcome these limitations. For instance, the introduction of solubilizing groups or the development of prodrugs are being explored to enhance the pharmacokinetic properties of these compounds.

In conclusion, the study of 1033203-56-3 and 4-methoxy-2-nitro-Pyridine continues to be a vibrant area of research with significant implications for both academia and industry. The latest findings underscore their potential as versatile tools in drug discovery and material science, while also highlighting the need for further optimization to address existing challenges. As research progresses, these compounds are expected to play an increasingly important role in advancing chemical biology and pharmaceutical sciences.

Recommended suppliers
煙臺朗裕新材料科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Jiangsu Kolod Food Ingredients Co.,ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangsu Kolod Food Ingredients Co.,ltd
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
SHOCHEM(SHANGHAI) CO.,lTD
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.