Cas no 1027-91-4 (1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide)

1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide is a piperidine derivative with potential applications in pharmaceutical and chemical research. Its structure features a benzyl group at the 1-position and an ethylamino substituent at the 4-position, contributing to its unique reactivity and binding properties. The carboxylic acid amide moiety enhances its solubility and stability, making it suitable for further synthetic modifications. This compound may serve as an intermediate in the development of bioactive molecules, particularly in CNS-targeted therapies due to its piperidine scaffold. Its well-defined stereochemistry and functional group diversity offer versatility for medicinal chemistry applications. Proper handling and storage under inert conditions are recommended to maintain its integrity.
1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide structure
1027-91-4 structure
Product Name:1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide
CAS No:1027-91-4
MF:C15H23N3O
MW:261.36262345314
MDL:MFCD00023758
CID:188165
PubChem ID:70567
Update Time:2025-11-03

1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide Chemical and Physical Properties

Names and Identifiers

    • 1-Benzyl-4-(ethylamino)piperidine-4-carboxamide
    • 4-Piperidinecarboxamide,4-(ethylamino)-1-(phenylmethyl)-
    • N-BENZYL-4-CARBAMYL-4-N-ETHYLAMINOPIPERIDINE
    • 1-benzyl-4-carbamoyl-4-(ethylamino)piperidine
    • 1-Benzyl-4-carbamoyl-4-ethylamino-piperidin
    • 1-Benzyl-4-ethylamino-4-carbamoyl-piperidin
    • 1-benzyl-4-ethylamino-piperidine-4-carboxylic acid amide
    • HMS3085D05
    • 1-(benzyl)-4-(ethylamino)isonipecotamide
    • 1-BENZYL-4-ETHYLAMINO-4-PIPERIDINECARBOXAMIDE
    • 4-Ethylamino-1-phenylmethyl-4-piperidinecarboxamide
    • 4-(ethylamino)-1-(phenylmethyl)piperidine-4-carboxamide
    • SB30252
    • 1027-91-4
    • SMR001559751
    • 1-Benzyi-4-ethylaminopiperidine-4-carboxylic Acid Amide
    • NSC72999
    • EINECS 213-839-4
    • MLS002693810
    • SCHEMBL971337
    • DTXSID60145461
    • NS00023179
    • NSC 72999
    • CS-0440192
    • 4-Piperidinecarboxamide, 4-(ethylamino)-1-(phenylmethyl)-
    • NSC-72999
    • 1-Benzyl-4-ethylaminopiperidine-4-carboxylic Acid Amide
    • LPPPBYXGXSHYQJ-UHFFFAOYSA-N
    • AKOS010001772
    • 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide
    • MDL: MFCD00023758
    • Inchi: 1S/C15H23N3O/c1-2-17-15(14(16)19)8-10-18(11-9-15)12-13-6-4-3-5-7-13/h3-7,17H,2,8-12H2,1H3,(H2,16,19)
    • InChI Key: LPPPBYXGXSHYQJ-UHFFFAOYSA-N
    • SMILES: O=C(C1(CCN(CC2C=CC=CC=2)CC1)NCC)N

Computed Properties

  • Exact Mass: 261.18400
  • Monoisotopic Mass: 261.184112
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 5
  • Complexity: 292
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 58.4
  • XLogP3: 1

Experimental Properties

  • Density: 1.11
  • Boiling Point: 432.8°Cat760mmHg
  • Flash Point: 215.5°C
  • Refractive Index: 1.577
  • PSA: 58.36000
  • LogP: 2.14510

1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide

1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide: A Comprehensive Overview

The compound with CAS No. 1027-91-4, commonly referred to as 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide, is a significant molecule in the field of organic chemistry and pharmacology. This compound has garnered attention due to its unique structural properties and potential applications in drug development. Recent studies have highlighted its role in various therapeutic areas, making it a subject of interest for researchers and industry professionals alike.

1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide is characterized by its complex structure, which includes a piperidine ring substituted with a benzyl group and an ethylamino moiety. The presence of these functional groups contributes to its versatility in chemical reactions and biological interactions. Researchers have explored its synthesis through various routes, including nucleophilic substitution and coupling reactions, which have been optimized to enhance yield and purity.

Recent advancements in computational chemistry have enabled detailed studies of the compound's electronic structure and molecular dynamics. These studies have provided insights into its stability, reactivity, and potential interactions with biological systems. For instance, molecular docking simulations have revealed that 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide exhibits strong binding affinity to certain protein targets, suggesting its potential as a lead compound in drug discovery.

In terms of pharmacological applications, this compound has shown promise in several areas. Preclinical studies indicate that it may possess anti-inflammatory and analgesic properties, making it a candidate for the development of new pain management therapies. Additionally, its ability to modulate neurotransmitter systems has led to investigations into its potential role in treating neurological disorders such as epilepsy and Parkinson's disease.

The synthesis of 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide involves a series of well-defined steps that ensure the formation of the desired product with high fidelity. Recent research has focused on improving the efficiency of these reactions, particularly through the use of catalytic systems and green chemistry principles. These advancements not only reduce production costs but also minimize environmental impact, aligning with current industry trends toward sustainability.

Moreover, the compound's structural versatility has opened avenues for further modification and functionalization. By introducing additional substituents or altering existing groups, researchers can tailor its properties for specific applications. For example, the introduction of hydrophilic groups may enhance its solubility and bioavailability, while hydrophobic modifications could improve its membrane permeability.

In conclusion, 1-Benzyl-4-ethylamino-piperidine-4-carboxylic Acid Amide (CAS No. 1027-91-4) is a multifaceted compound with significant potential in both academic research and industrial applications. Its unique structure, coupled with recent advancements in synthesis and pharmacology, positions it as a valuable tool in the development of novel therapeutic agents. As research continues to unfold, this compound is expected to play an increasingly important role in addressing unmet medical needs.

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