Cas no 102418-06-4 (Neospiramycin)

Neospiramycin is a macrolide antibiotic derived from spiramycin, characterized by its broad-spectrum activity against Gram-positive bacteria and certain Gram-negative pathogens. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. Neospiramycin exhibits enhanced stability and improved pharmacokinetic properties compared to its parent compound, resulting in better bioavailability and prolonged therapeutic effects. It is particularly effective in treating respiratory tract infections, skin infections, and sexually transmitted diseases caused by susceptible organisms. The compound's low toxicity profile and reduced incidence of resistance development make it a reliable option in clinical and veterinary applications. Its formulation versatility allows for oral, topical, or injectable administration.
Neospiramycin structure
Neospiramycin structure
Product Name:Neospiramycin
CAS No:102418-06-4
MF:C36H62N2O11
MW:698.884292125702
CID:148937
PubChem ID:6441781
Update Time:2025-08-10

Neospiramycin Chemical and Physical Properties

Names and Identifiers

    • Neospiramycin
    • 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2
    • [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6R)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
    • Leucomycin V, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-, (9(2R,5S,6R))-
    • Neospiramycin I
    • 102418-06-4
    • 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
    • 70253-62-2
    • DTXSID001016175
    • Inchi： 1S/C36H62N2O11/c1-21-19-25(17-18-39)34(49-36-33(43)31(38(7)8)32(42)24(4)47-36)35(44-9)27(40)20-29(41)45-22(2)13-11-10-12-14-28(21)48-30-16-15-26(37(5)6)23(3)46-30/h10-12,14,18,21-28,30-36,40,42-43H,13,15-17,19-20H2,1-9H3/b11-10+,14-12+/t21-,22-,23-,24-,25+,26+,27-,28+,30+,31+,32-,33-,34+,35+,36+/m1/s1
    • InChI Key： SUBWVHAACKTENX-XLGVTROISA-N
    • SMILES： O([C@H]1[C@@H]([C@H]([C@@H]([C@@H](C)O1)O)N(C)C)O)[C@@H]1[C@H]([C@@H](CC(=O)O[C@H](C)CC=CC=C[C@@H]([C@H](C)C[C@@H]1CC=O)O[C@H]1CC[C@@H]([C@@H](C)O1)N(C)C)O)OC |t:24,26|

Computed Properties

  • Exact Mass: 698.435361g/mol
  • Monoisotopic Mass: 698.435361g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 13
  • Heavy Atom Count: 49
  • Rotatable Bond Count: 9
  • Complexity: 1070
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 15
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 2
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 698.9g/mol
  • XLogP3: 2
  • Topological Polar Surface Area: 157?2

Neospiramycin Security Information

  • Safety Term：x."> Poison by intravenous route. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.

Neospiramycin Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
N102410-10mg
Neospiramycin
 102418-06-4
10mg
 120.00 2021-07-26
TRC
N102410-50mg
Neospiramycin
 102418-06-4
50mg
 495.00 2021-07-26
TRC
N102410-100mg
Neospiramycin
 102418-06-4
100mg
 960.00 2021-07-26

Neospiramycin Related Literature

102418-06-4 (Neospiramycin) Related Products

Recommended suppliers
Shanghai Joy Biotech Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Joy Biotech Ltd
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
Changzhou Guanjia Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Changzhou Guanjia Chemical Co., Ltd
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司