Cas no 1392-21-8 (Leucomycin)

Leucomycin is a macrolide antibiotic derived from Streptomyces kitasatoensis, primarily effective against Gram-positive bacteria and some Gram-negative strains. It exhibits bacteriostatic activity by inhibiting protein synthesis through binding to the 50S ribosomal subunit. Leucomycin is notable for its broad-spectrum efficacy, particularly against respiratory and dermal infections caused by susceptible organisms. Its stability in acidic conditions and favorable pharmacokinetic profile enhance its therapeutic utility. The compound is often utilized in veterinary and agricultural applications due to its low toxicity and residual effects. Leucomycin's structural analogs, such as kitasamycin, further expand its applicability in antimicrobial therapy.
Leucomycin structure
Leucomycin structure
Product Name:Leucomycin
CAS No:1392-21-8
MF:C35H59NO13
MW:701.84187245369
MDL:MFCD01314545
CID:41313
PubChem ID:53394899
Update Time:2025-06-07

Leucomycin Chemical and Physical Properties

Names and Identifiers

    • Sineptina
    • LEUCOMYCIN HYDRATE
    • KITASAMYCIN BASE
    • KITASAMYCIN
    • FORMACIDINE
    • ayermicina
    • c637
    • selectomycin
    • Leucomycin Base
    • Ayermycin
    • Leucomycin A1
    • Stereomycine
    • Syneptine
    • Leucomycins
    • Leucomycin
    • 1392-21-8
    • 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
    • Leucomycin V
    • Antibiotic JA-6599
    • 22875-15-6
    • CHEBI:31753
    • OXACYCLOHEXADECA-11,13-DIENE-7-ACETALDEHYDE, 6-((3,6-DIDEOXY-4-O-(2,6-DIDEOXY-3-C-METHYL-.ALPHA.-L-RIBO-HEXOPYRANOSYL)-3-(DIMETHYLAMINO)-.BETA.-D-GLUCOPYRANOSYL)OXY)-4,10-DIHYDROXY-5-METHOXY-9,16-DIMETHYL-2-OXO-, (4R-(4R*,5S*,6S*,7R*,9R*,10R*,11E,13E,16R*))-
    • Deisovaleryl leucomycin A1
    • 2-[(4R, 5S, 6S, 7R, 9R, 10R, 11E, 13E, 16R)-6-[(2S, 3R, 4R, 5S, 6R)-5-[(2S, 4R, 5S, 6S)-4, 5-dihydroxy-4, 6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4, 10-dihydroxy-5-methoxy-9, 16-dimethyl-2-oxo-1-oxacyclohexadeca-11, 13-dien-7-yl]acetaldehyde
    • Glucopyranoside, 7-(formylmethyl)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-6-yl 3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-, beta-D-
    • SCHEMBL5035766
    • VW9SY2S5WL
    • 4''-Deacylturimycin H
    • 39405-35-1
    • Deacylleucomycin A1
    • GLUCOPYRANOSIDE, 7-(FORMYLMETHYL)-4,10-DIHYDROXY-5-METHOXY-9,16-DIMETHYL-2-OXOOXACYCLOHEXADECA-11,13-DIEN-6-YL 3,6-DIDEOXY-4-O-(2,6-DIDEOXY-3-C-METHYL-.ALPHA.-L-RIBO-HEXOPYRANOSYL)-3-(DIMETHYLAMINO)-, .BETA.-D-
    • Turimycin
    • Antibiotic A 6599
    • DTXSID501043929
    • 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
    • [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
    • UNII-VW9SY2S5WL
    • A 6599
    • Q6417876
    • AKOS015896458
    • XYJOGTQLTFNMQG-KJHBSLKPSA-N
    • Quitasamicina (INN-Spanish)
    • Kitasamycine [INN-French]
    • LEUCOMYCIN [MI]
    • KITASAMYCIN [USAN]
    • AK65051
    • Kitasamycinum
    • Kitasamycinum (INN-Latin)
    • DTXSID601016678
    • Kitasamycinum [INN-Latin]
    • Kitasamycine (INN-French)
    • KITASAMYCIN [INN]
    • Leucomycin (TN)
    • KITASAMYCIN [WHO-DD]
    • 1392-21-8, Kitasamycin
    • KITASAMYCIN [JAN]
    • Quitasamicina
    • acetylkitasamycinum (acetyl derivative)
    • Quitasamicina [INN-Spanish]
    • C 637
    • Kitasamycin [USAN:INN:BAN:JAN]
    • G986N7X02W
    • MDL： MFCD01314545
    • Inchi： 1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1
    • InChI Key： XYJOGTQLTFNMQG-KJHBSLKPSA-N
    • SMILES： O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C)O[C@H]1C[C@](C)([C@H]([C@H](C)O1)O)O)N(C)C)O)O[C@@H]1[C@H]([C@@H](CC(=O)O[C@H](C)CC=CC=C[C@@H]([C@H](C)C[C@@H]1CC=O)O)O)OC |t:35,37|

Computed Properties

  • Exact Mass: 701.399
  • Monoisotopic Mass: 701.399
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 14
  • Heavy Atom Count: 49
  • Rotatable Bond Count: 8
  • Complexity: 1110
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 16
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 2
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 194A^2
  • Surface Charge: 0
  • Tautomer Count: 4
  • XLogP3: 0.5

Experimental Properties

  • Color/Form: White or yellow crystalline powder.
  • Density: 1.2500
  • Melting Point: 120-130°C
  • Boiling Point: 851.7 °C at 760 mmHg
  • Flash Point: 468.9 °C
  • Refractive Index: 1.532
  • Solubility: ethanol: 50?mg/mL, clear to slightly hazy, light-yellow
  • Solubility: It is easily soluble in methanol, ethanol, acetone, ether and chloroform, but poorly soluble in water.
  • Merck: 14,5453
  • Specific Rotation: -77.8° (c=1, MeOH)
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

Leucomycin Security Information

Leucomycin Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
L330320-250mg
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 $ 52.00 2023-09-07
TRC
L330320-5g
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SHANG HAI XIAN DING Biotechnology Co., Ltd.
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 ￥230.0 2022-02-28
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MedChemExpress
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S e l l e c k ZHONG GUO
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 ￥794.59 2023-10-30
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
L812531-50mg
Kitasamycin
 1392-21-8 98%(sum of isomers)
50mg
 ￥398.00 2022-01-13
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
L812531-100mg
Kitasamycin
 1392-21-8 98%(sum of isomers)
100mg
 ￥598.00 2022-01-13

Leucomycin Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:1392-21-8)Leucomycin
Order Number:LE13625
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
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Suzhou Senfeida Chemical Co., Ltd
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(CAS:1392-21-8)Sineptina
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Purity:99.9%
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Zhengzhou Baoyu Pharmaceutical Co., Ltd.
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(CAS:1392-21-8)Sineptina
Order Number:LE055
Stock Status:in Stock
Quantity:5KG/1KG/25KG/100KG
Purity:99% HPLC
Pricing Information Last Updated:Thursday, 14 August 2025 14:44
Price ($):negotiated

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Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:1392-21-8)Leucomycin
LE13625
Purity:99%
Quantity:25KG,200KG,1000KG
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Suzhou Senfeida Chemical Co., Ltd
(CAS:1392-21-8)Sineptina
sfd3382
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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