• 1. An intermolecular C–C coupling reaction of iridium complexes?
  Kathrin Kutlescha,Rhett Kempe New J. Chem., 2010,34, 1954-1960
• 2. An amphipathic trans-acting phosphorothioate RNA element delivers an uncharged phosphorodiamidate morpholino sequence in mdx mouse myotubes?
  H. V. Jain,D. Verthelyi,S. L. Beaucage RSC Adv., 2017,7, 42519-42528
• 3. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 4. An alternative biorefinery approach to address microalgal seasonality: blending with spent coffee grounds
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• Catalysts and Inorganic Chemicals Inorganic Compounds Mixed metal/non-metal compounds Alkali metal oxoanionic compounds Alkali metal phosphates
• Catalysts and Inorganic Chemicals Inorganic Compounds Salt

Sodium Phosphate Dibasic Dihydrate (CAS No. 10028-24-7): An Essential Compound in Chemical and Pharmaceutical Applications

Sodium Phosphate Dibasic Dihydrate (CAS No. 10028-24-7) is a versatile and widely used compound in various scientific and industrial applications, particularly in the fields of chemistry, biology, and pharmaceuticals. This compound, also known as disodium hydrogen phosphate dihydrate or Na₂HPO₄·2H₂O, is a white crystalline solid that is highly soluble in water. Its unique properties make it an indispensable reagent in numerous laboratory and industrial processes.

The chemical structure of Sodium Phosphate Dibasic Dihydrate consists of two sodium ions (Na⁺), one hydrogen phosphate ion (HPO₄^2-), and two water molecules (H₂O). This composition imparts the compound with several key characteristics, including its high solubility in water, its ability to form stable solutions, and its role as a buffer in maintaining pH levels. These properties are crucial in various applications, from buffer solutions in biochemical assays to pH control in pharmaceutical formulations.

In the realm of biochemical research, Sodium Phosphate Dibasic Dihydrate is frequently used as a component of buffer solutions. Buffers are essential for maintaining a stable pH environment, which is critical for the proper functioning of enzymes and other biological macromolecules. Recent studies have highlighted the importance of precise pH control in enzymatic reactions and cell culture media. For instance, a study published in the Journal of Biological Chemistry demonstrated that the use of Sodium Phosphate Dibasic Dihydrate-based buffers significantly improved the stability and activity of certain enzymes under varying conditions.

In pharmaceutical applications, Sodium Phosphate Dibasic Dihydrate plays a vital role in the formulation of various drugs and drug delivery systems. Its ability to maintain pH levels ensures that active pharmaceutical ingredients (APIs) remain stable and effective throughout their shelf life. Additionally, the compound's solubility properties make it an excellent choice for preparing injectable solutions and oral suspensions. A recent review in the International Journal of Pharmaceutics discussed the use of Sodium Phosphate Dibasic Dihydrate in enhancing the bioavailability of poorly soluble drugs through pH-mediated solubilization techniques.

The industrial applications of Sodium Phosphate Dibasic Dihydrate are equally diverse. In food processing, it is used as a leavening agent and pH regulator to improve texture and shelf life. In water treatment, it serves as a corrosion inhibitor by forming protective layers on metal surfaces. In cleaning products, it acts as a chelating agent to remove hard water deposits and stains. These multifaceted uses underscore the compound's versatility and importance across multiple industries.

The safety profile of Sodium Phosphate Dibasic Dihydrate is well-established, making it suitable for use in both laboratory settings and consumer products. However, like any chemical compound, it should be handled with appropriate precautions to ensure user safety. Proper storage conditions, such as keeping it away from moisture and incompatible materials, are essential to maintain its stability and effectiveness.

In conclusion, Sodium Phosphate Dibasic Dihydrate (CAS No. 10028-24-7) is a fundamental compound with a wide range of applications in chemical, biological, and pharmaceutical research and development. Its unique properties make it an invaluable reagent for maintaining pH stability, enhancing drug formulations, and supporting various industrial processes. As research continues to uncover new applications and optimize existing ones, the importance of this compound is likely to grow even further.

• 10039-32-4(Phosphoric acid disodium dodecahydrate)
• 7632-05-5(Sodium phosphate)
• 13472-35-0(Phosphoric Acid Monosodium Salt Dihydrate)
• 7558-80-7(Dihydrogen monosodium phosphate)
• 7558-79-4(Disodium phosphate)
• 7601-54-9(Sodium Phosphate)
• 10101-89-0(Trisodium phosphate dodecahydrate)
• 89140-32-9(sodium dihydrogen phosphate anhydrous)
• 15819-50-8(Trisodium phosphate hexahydrate)
• 10049-21-5(Sodium phosphate monobasic monohydrate)