Chemoselective recognition with phosphonate cavitands: the ephedrine over pseudoephedrine case?

Chemical Communications Pub Date: 2015-01-20 DOI: 10.1039/C4CC09387A

Abstract

Complete discrimination of ephedrine and pseudoephedrine, both in solution and in the solid state, was achieved with a phosphonate cavitand receptor. The molecular origin of the epimer discrimination was revealed by the crystal structure of the respective complexes.

Graphical abstract: Chemoselective recognition with phosphonate cavitands: the ephedrine over pseudoephedrine case
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